AAMP (gene)
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AAMP (gene)
Angio-associated, migratory cell protein, also known as AAMP, is a protein which in humans is encoded by the ''AAMP'' gene. This protein has been conserved in evolution and is so common to many mammals. and it also has a yeast homolog which is the protein YCR072c. Localisation The gene is located on the second human chromosome, near the end of the chromosome's arm (2q35), between the codons 85-87 and 1387–1389. It contains 6042 bp and 11 exons When transcribed, it gives a 1859 bp mRNA. . The vascular endothelial growth factor is a promoting factor of the protein synthesis and localisation in the different parts of the cells. The protein's expression is higher in the intracellular than in the extracellular space. Function The gene product is an immunoglobulin-type protein of 434 amino acids and 49 kDa. It is found to be expressed strongly in the cytosol of endothelial cells, cytotrophoblasts, and poorly differentiated colon adenocarcinoma cells found in lymphatics and h ...
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Protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, responding to stimuli, providing structure to cells and organisms, and transporting molecules from one location to another. Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the nucleotide sequence of their genes, and which usually results in protein folding into a specific 3D structure that determines its activity. A linear chain of amino acid residues is called a polypeptide. A protein contains at least one long polypeptide. Short polypeptides, containing less than 20–30 residues, are rarely considered to be proteins and are commonly called peptides. The individual amino acid residues are bonded together by peptide bonds and adjacent amino acid residues. The sequence of amino acid ...
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