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Ayre Spatula
The Ayre spatula is a device used to collect Pap smear. It is a wooden spatula with U shaped openings on one side and a flat surface on another. The broad end is for vaginal sample collection and the narrow end is for cervical sample collection. It is rotated 360 degrees in the vagina to obtain the cells to be sent for Pap smear examination. Recent studies have shown that long-tipped spatulas ( Aylesbury device) or a cytobrush along with an extended-tip spatula are better than an Ayre spatula in collecting endocervical cells. However, the Ayre spatula continues to be used for cervical sample collection in lower-income countries. The Ayre spatula is introduced into the cervix after exposing the external os using a speculum. The cytology specimens are obtained by rotating the spatula firmly over the ectocervix and quickly transferring the cells to a slide or jar. The Ayre spatula was invented by James Ernest Ayre and Georgios Papanikolaou. Ayre was granted a patent for it in 1949 ...
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Medical Instruments O&G Ayre's Spatula And Slide Holding Bottle
Medicine is the science and practice of caring for a patient, managing the diagnosis, prognosis, prevention, treatment, palliation of their injury or disease, and promoting their health. Medicine encompasses a variety of health care practices evolved to maintain and restore health by the prevention and treatment of illness. Contemporary medicine applies biomedical sciences, biomedical research, genetics, and medical technology to diagnose, treat, and prevent injury and disease, typically through pharmaceuticals or surgery, but also through therapies as diverse as psychotherapy, external splints and traction, medical devices, biologics, and ionizing radiation, amongst others. Medicine has been practiced since prehistoric times, and for most of this time it was an art (an area of skill and knowledge), frequently having connections to the religious and philosophical beliefs of local culture. For example, a medicine man would apply herbs and say prayers for healing, or an ancie ...
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Pap Smear
The Papanicolaou test (abbreviated as Pap test, also known as Pap smear (AE), cervical smear (BE), cervical screening (BE), or smear test (BE)) is a method of cervical screening used to detect potentially precancerous and cancerous processes in the cervix (opening of the uterus or womb) or Colon (organ), colon (in both men and women). Abnormal findings are often followed up by more sensitive diagnostic procedures and, if warranted, interventions that aim to prevent progression to cervical cancer. The test was independently invented in the 1920s by Georgios Papanikolaou and Aurel Babeș and named after Papanikolaou. A simplified version of the test was introduced by Anna Marion Hilliard in 1957. A Pap smear is performed by opening the vagina with a speculum (medical), speculum and collecting cell (biology), cells at the outer opening of the cervix at the transformation zone (where the outer squamous cervical cells meet the inner glandular endocervical cells), using an Ayre spatula ...
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Aylesbury Device
Aylesbury ( ) is the county town of Buckinghamshire, South East England. It is home to the Roald Dahl Children's Gallery, David Tugwell`s house on Watermead and the Waterside Theatre. It is in central Buckinghamshire, midway between High Wycombe and Milton Keynes. Aylesbury was awarded Garden Town status in 2017. The housing target for the town is set to grow with 16,000 homes set to be built by 2033. History The town name is of Old English origin. Its first recorded name ''Æglesburgh'' is thought to mean "Fort of Ægel", though who Ægel was is not recorded. It is also possible that ''Ægeles-burh'', the settlement's Saxon name, means "church-burgh", from the Welsh word ''eglwys'' meaning "a church" (< ''ecclesia''). Excavations in the town centre in 1985 found an

Cytobrush
A cytobrush is a plastic tool used to obtain cells from the cervix during the procedure of a pap smear The Papanicolaou test (abbreviated as Pap test, also known as Pap smear (AE), cervical smear (BE), cervical screening (BE), or smear test (BE)) is a method of cervical screening used to detect potentially precancerous and cancerous processes in t .... File:Cytobrush.jpg, Cytobrush File:Cytobrush_for_sampling_endocervical_cells.jpg, Cytobrush for sampling endocervical cells File:Labeled pap bush uterine.png, Diagram of cytobrush in vagina/cervix References Surgical instruments Gynaecology {{gynaecology-stub ...
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Endocervix
The cervical canal is the spindle-shaped, flattened canal of the cervix, the neck of the uterus. Anatomy The cervical canal communicates with the uterine cavity via the internal orifice of the uterus (or internal os) and with the vagina via the external orifice of the uterus (ostium of uterus or external os). The internal orifice of the uterus is an interior narrowing of the uterine cavity. It corresponds to a slight constriction known as the ''isthmus'' that can be seen on the surface of the uterus about midway between the apex and base. The external orifice of the uterus is a small, depressed, somewhat circular opening on the rounded extremity of the cervix, opening to the vagina. Through this aperture, the cervical cavity communicates with that of the vagina. The external orifice is bounded by two lips, an anterior and a posterior. The anterior is shorter and thicker, though it projects lower than the posterior because of the slope of the cervix. Normally, both lips are in c ...
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Speculum (medical)
A speculum (Latin for 'mirror'; plural specula or speculums) is a medical tool for investigating body orifices, with a form dependent on the orifice for which it is designed. In old texts, the speculum may also be referred to as a diopter or dioptra. Like an endoscope, a speculum allows a view inside the body; endoscopes, however, tend to have optics while a speculum is intended for direct vision. History Vaginal and anal specula were used by the ancient Greeks and Romans, and speculum artifacts have been found in Pompeii. A vaginal speculum, developed by J. Marion Sims, consists of a hollow cylinder with a rounded end that is divided into two hinged parts, somewhat like the beak of a duck. This speculum is inserted into the vagina to dilate it for examination of the vagina and cervix. The modern vaginal speculum was developed by J. Marion Sims, a plantation doctor in Lancaster County, South Carolina. Between 1845 and 1849, Sims performed dozens of surgeries, without anesthes ...
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Cytology
Cell biology (also cellular biology or cytology) is a branch of biology that studies the structure, function, and behavior of cells. All living organisms are made of cells. A cell is the basic unit of life that is responsible for the living and functioning of organisms. Cell biology is the study of structural and functional units of cells. Cell biology encompasses both prokaryotic and eukaryotic cells and has many subtopics which may include the study of cell metabolism, cell communication, cell cycle, biochemistry, and cell composition. The study of cells is performed using several microscopy techniques, cell culture, and cell fractionation. These have allowed for and are currently being used for discoveries and research pertaining to how cells function, ultimately giving insight into understanding larger organisms. Knowing the components of cells and how cells work is fundamental to all biological sciences while also being essential for research in biomedical fields such as ca ...
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Cervix
The cervix or cervix uteri (Latin, 'neck of the uterus') is the lower part of the uterus (womb) in the human female reproductive system. The cervix is usually 2 to 3 cm long (~1 inch) and roughly cylindrical in shape, which changes during pregnancy. The narrow, central cervical canal runs along its entire length, connecting the uterine cavity and the lumen of the vagina. The opening into the uterus is called the internal os, and the opening into the vagina is called the external os. The lower part of the cervix, known as the vaginal portion of the cervix (or ectocervix), bulges into the top of the vagina. The cervix has been documented anatomically since at least the time of Hippocrates, over 2,000 years ago. The cervical canal is a passage through which sperm must travel to fertilize an egg cell after sexual intercourse. Several methods of contraception, including cervical caps and cervical diaphragms, aim to block or prevent the passage of sperm through the cervical ...
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James Ernest Ayre
National Cancer Center ("NCC" or "Center"), founded in 1953, is a (501)(c)(3) not-for-profit organization in the United States that funds young cancer researchers who are working to discover how the body's immune system sees and responds to cancer when it initially develops and why certain cancer cells are resistant to different treatments. The organization also provides educational information to the public on the prevention, diagnosis and treatment of cancer. Grants are awarded based on the recommendations of NCC's Scientific Advisory Board, which uses National Institutes of Health evaluation standards. Scientific Advisory Board members are cancer research professionals, headed by Dr. Darell Bigner, founder and director of Duke University’s Preston Robert Tisch Brain Tumor Center, the largest brain tumor research facility in the country. Other Grant Review Committee members represent such institutions as the Dana-Farber Cancer Institute, the University of Pittsburgh Cancer ...
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Georgios Papanikolaou
Georgios Nikolaou Papanikolaou (or George Papanicolaou ; el, Γεώργιος Ν. Παπανικολάου ; 13 May 1883 – 19 February 1962) was a Greek physician who was a pioneer in cytopathology and early cancer detection, and inventor of the "Pap smear". After studying medicine in Greece and Germany, he emigrated in 1913 to the United States. He first reported that uterine cancer cells could be detected in vaginal smears in 1928, but his work was not widely recognized until the 1940s. An extensive trial of his techniques was carried out in the early 1950s. In 1961, he was invited to the University of Miami to lead and develop the Papanicolaou Cancer Research Institute there. Life Born in Kymi, Greece, Papanikolaou attended the University of Athens, where he studied literature, philosophy, languages and music. Urged by his father, he pursued a medical degree, which he received in 1904. Afterwards, he was conscripted into military service. When his obligation ended in 19 ...
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American Cancer Society
The American Cancer Society (ACS) is a nationwide voluntary health organization dedicated to eliminating cancer. Established in 1913, the society is organized into six geographical regions of both medical and lay volunteers operating in more than 250 Regional offices throughout the United States. Its global headquarters is located in the American Cancer Society Center in Atlanta, Georgia. The ACS publishes the journals ''Cancer'', '' CA: A Cancer Journal for Clinicians'' and ''Cancer Cytopathology''. History The society was founded on May 22, 1913, by ten physicians and five businessmen in New York City under the name "American Society for the Control of Cancer" (ASCC). The current name was adopted in 1944. At the time of founding, it was not considered appropriate to mention the word "cancer" in public. Information concerning this illness was cloaked in a climate of fear and denial. Over 75,000 people died each year of cancer in just the United States. The top item on the foun ...
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Surgical Instruments
A surgical instrument is a tool or device for performing specific actions or carrying out desired effects during a surgery or operation, such as modifying biological tissue, or to provide access for viewing it. Over time, many different kinds of surgical instruments and tools have been invented. Some surgical instruments are designed for general use in all sorts of surgeries, while others are designed for only certain specialties or specific procedures. Classification of surgical instruments helps surgeons to understand the functions and purposes of the instruments. With the goal of optimizing surgical results and performing more difficult operations, more instruments continue to be invented in the modern era. History Many different kinds of surgical instruments and tools have been invented and some have been repurposed as medical knowledge and surgical practices have developed. As surgery practice diversified, some tools are advanced for higher accuracy and stability while so ...
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