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Atul Butte
Atul J. Butte is a biomedical informatics researcher and biotechnology entrepreneur. He is currently the Priscilla Chan and Mark Zuckerberg Distinguished Professor at the University of California, San Francisco. Since April 2015, Butte has serves as inaugural director of UCSF's Bakar Computational Health Sciences Institute. Previously, Butte was Chief of the Division of Systems Medicine at Stanford University School of Medicine and Lucile Packard Children's Hospital where he held the position of an associate professor of pediatrics and (by courtesy) computer science and immunology & rheumatology. Education Butte attended Brown University, where he studied computer science as an undergrad. As a member of the school's Program in Liberal Medical Education he was guaranteed acceptance to Brown's Alpert Medical School, where he obtained his MD in 1995. Butte completed a residency in pediatrics and a fellowship in pediatric endocrinology, both at Children's Hospital Boston. In 2004, ...
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Bioinformatics
Bioinformatics () is an interdisciplinary field that develops methods and software tools for understanding biological data, in particular when the data sets are large and complex. As an interdisciplinary field of science, bioinformatics combines biology, chemistry, physics, computer science, information engineering, mathematics and statistics to analyze and interpret the biological data. Bioinformatics has been used for '' in silico'' analyses of biological queries using computational and statistical techniques. Bioinformatics includes biological studies that use computer programming as part of their methodology, as well as specific analysis "pipelines" that are repeatedly used, particularly in the field of genomics. Common uses of bioinformatics include the identification of candidates genes and single nucleotide polymorphisms (SNPs). Often, such identification is made with the aim to better understand the genetic basis of disease, unique adaptations, desirable properties (e ...
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University Of California, San Francisco
The University of California, San Francisco (UCSF) is a public land-grant research university in San Francisco, California. It is part of the University of California system and is dedicated entirely to health science and life science. It conducts research and teaching in medical and biological sciences. UCSF was founded as Toland Medical College in 1864. in 1873, it became affiliated with the University of California as its Medical Department. In the same year, it incorporated the California College of Pharmacy and in 1881 it established a dentistry school. Its facilities were located in both Berkeley and San Francisco. In 1964, the school gained full administrative independence as a campus of the UC system, headed by its own chancellor, and in 1970 it gained its current name. Historically based at Parnassus Heights with satellite facilities throughout the city, UCSF developed a second major campus in the newly redeveloped Mission Bay district in the early 2000s. '' U.S. N ...
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Microarray
A microarray is a multiplex lab-on-a-chip. Its purpose is to simultaneously detect the expression of thousands of genes from a sample (e.g. from a tissue). It is a two-dimensional array on a solid substrate—usually a glass slide or silicon thin-film cell—that assays (tests) large amounts of biological material using high-throughput screening miniaturized, multiplexed and parallel processing and detection methods. The concept and methodology of microarrays was first introduced and illustrated in antibody microarrays (also referred to as antibody matrix) by Tse Wen Chang in 1983 in a scientific publication and a series of patents. The "gene chip" industry started to grow significantly after the 1995 ''Science Magazine'' article by the Ron Davis and Pat Brown labs at Stanford University. With the establishment of companies, such as Affymetrix, Agilent, Applied Microarrays, Arrayjet, Illumina, and others, the technology of DNA microarrays has become the most sophisticated and ...
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Publons
Publons was a commercial website that provided a free service for academics to track, verify, and showcase their peer review and editorial contributions for academic journals. It was launched in 2012 and was bought by Clarivate in 2017. It claimed that over 3,000,000 researchers joined the site, adding more than one million reviews across 25,000 journals. In 2019, ResearcherID was integrated with Publons. Publons produced a verified record of a person's review and editorial activity for journals, which could be downloaded to include in CVs, funding and job applications, and promotion and performance evaluations. Publons' business model was based on partnering with publishers. Background Publons was founded by Andrew Preston and Daniel Johnston to address the static state of peer-reviewing practices in academic research publishing, in view of encouraging collaboration and speeding scientific development. The Publons name was an homage to the "publon", the "Least publishable unit, ...
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H-index
The ''h''-index is an author-level metric that measures both the productivity and citation impact of the publications, initially used for an individual scientist or scholar. The ''h''-index correlates with obvious success indicators such as winning the Nobel Prize, being accepted for research fellowships and holding positions at top universities. The index is based on the set of the scientist's most cited papers and the number of citations that they have received in other publications. The index has more recently been applied to the productivity and impact of a scholarly journal as well as a group of scientists, such as a department or university or country. The index was suggested in 2005 by Jorge E. Hirsch, a physicist at UC San Diego, as a tool for determining theoretical physicists' relative quality and is sometimes called the Hirsch index or Hirsch number. Definition and purpose The ''h''-index is defined as the maximum value of ''h'' such that the given author/journa ...
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Isaac Kohane
Isaac; grc, Ἰσαάκ, Isaák; ar, إسحٰق/إسحاق, Isḥāq; am, ይስሐቅ is one of the three patriarchs of the Israelites and an important figure in the Abrahamic religions, including Judaism, Christianity, and Islam. He was the son of Abraham and Sarah, the father of Jacob and Esau, and the grandfather of the twelve tribes of Israel. Isaac's name means "he will laugh", reflecting the laughter, in disbelief, of Abraham and Sarah, when told by God that they would have a child., He is the only patriarch whose name was not changed, and the only one who did not move out of Canaan. According to the narrative, he died aged 180, the longest-lived of the three patriarchs. Etymology The anglicized name "Isaac" is a transliteration of the Hebrew name () which literally means "He laughs/will laugh." Ugaritic texts dating from the 13th century BCE refer to the benevolent smile of the Canaanite deity El. Genesis, however, ascribes the laughter to Isaac's parents, Abrah ...
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Children's Hospital Boston
Boston Children's Hospital formerly known as Children's Hospital Boston until 2012 is a nationally ranked, freestanding acute care children's hospital located in Boston, Massachusetts, adjacent both to its teaching affiliate, Harvard Medical School, and to Dana–Farber Cancer Institute. Dana–Farber and Children's jointly operate the Dana–Farber/Boston Children's Cancer and Blood Disorders Center to deliver comprehensive care for all types of childhood cancers. The hospital is home to the largest hospital-based pediatric research program in the world. The hospital features 485 pediatric beds and provides comprehensive pediatric specialties and subspecialties to infants, children, teens, and young adults aged 0–21 throughout Massachusetts, the United States, and the world. The hospital also sometimes treats adults that require pediatric care. The hospital uses the Brigham and Women's Hospital's rooftop helipad and is an ACS verified level I pediatric trauma center, one of ...
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Alpert Medical School
The Warren Alpert Medical School (formerly known as Brown Medical School, previously known as Brown University School of Medicine) is the medical school of Brown University, located in Providence, Rhode Island. Originally established in 1811, it was the third medical school to be founded in New England after only Harvard and Dartmouth. However, the original program was suspended in 1827, and the four-year medical program was re-established almost 150 years later in 1972, granting the first MD degrees in 1975. Today, the Warren Alpert Medical School is a component of Brown’s Division of Biology and Medicine, which also includes the Program in Biology. Together with the Medical School’s seven affiliated teaching hospitals, the Division attracts over $300 million in external research funding per year. Alpert Medical School earned ranked 14th for primary care education and 35th for research in the 2023 ''U.S. News & World Report'' rankings, and was ranked among the top 25 medic ...
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Program In Liberal Medical Education
The Program in Liberal Medical Education, or PLME, is an eight-year combined baccalaureate-M.D. medical program offered by Brown University. Members of the program are simultaneously accepted into both the undergraduate College of Brown University as well as the Warren Alpert Medical School, allowing them to receive a Bachelor's degree and an M.D. as part of a single eight-year continuum. The PLME is the only combined medical program in the Ivy League, as well as one of only approximately 120 in the nation. The program is extremely selective, admitting only 90 applicants nationwide and internationally each year, with an acceptance rate of 2.19% for the class of 2026. The PLME is widely considered to be one of the most competitive and prestigious combined medical programs in the country. History The 8-year Program in Liberal Medical Education, was inaugurated in 1984. Since 1963, the university had offered a 6-year combined undergraduate/Master of Medical Science program. The PL ...
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Rheumatology
Rheumatology (Greek ''ῥεῦμα'', ''rheûma'', flowing current) is a branch of medicine devoted to the diagnosis and management of disorders whose common feature is inflammation in the bones, muscles, joints, and internal organs. Rheumatology covers more than 100 different complex diseases, collectively known as rheumatic diseases, which includes many forms of arthritis as well as lupus and Sjögren's syndrome. Doctors who have undergone formal training in rheumatology are called rheumatologists. Many of these diseases are now known to be disorders of the immune system, and rheumatology has significant overlap with immunology, the branch of medicine that studies the immune system. Rheumatologist A rheumatologist is a physician who specializes in the field of medical sub-specialty called rheumatology. A rheumatologist holds a board certification after specialized training. In the United States, training in this field requires four years undergraduate school, four year ...
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Immunology
Immunology is a branch of medicineImmunology for Medical Students, Roderick Nairn, Matthew Helbert, Mosby, 2007 and biology that covers the medical study of immune systems in humans, animals, plants and sapient species. In such we can see there is a difference of human immunology and comparative immunology in veterinary medicine and animal biosciences. Immunology measures, uses charts and differentiate in context in medicine the studies of immunity on cell and molecular level, and the immune system as part of the physiological level as its functioning is of major importance. In the different states of both health, occurring symptoms and diseases; the functioning of the immune system and immunological responses such as autoimmune diseases, allergic hypersensitivities, or in some cases malfunctioning of immune system as for example in immunological disorders or in immune deficiency, and the specific transplant rejection) Immunology has applications in numerous disciplines of ...
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