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Arnault Tzanck
Arnault Tzanck (1886–1954) was a French physician and a pioneer of blood transfusion. During the First World War, he was a doctor in the military ambulance where he realized the vital role of the blood transfusions. Arnault Tzanck's name is attached to an apparatus he invented that was widely used for transfusing blood in France between the wars, as well as a simple test he devised using the microscopic analysis of scrapings from skin cancer lesions, different ganglia, and some forms of dermatitis especially pemphigus. The Tzanck smear is still widely used as a test for herpes, among other diseases. A deep learning model was developed to analyze Tzanck smears and named after him as ''TzanckNet''. He also experimented with different methods of preserving blood and blood substitutes. Tzanck's most lasting contribution was in the organization of blood transfusion in France that eventually resulted in the creation of the Centre National de Transfusion Sanguine (National Blood Transfus ...
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Vladikavkaz
Vladikavkaz (russian: Владикавка́з, , os, Дзæуджыхъæу, translit=Dzæwdžyqæw, ;), formerly known as Ordzhonikidze () and Dzaudzhikau (), is the capital city of the North Ossetia-Alania, Republic of North Ossetia-Alania, Russia. It is located in the southeast of the republic at the foothills of the Caucasus Mountains, situated on the Terek River. The city's population was 311,693 as of the Russian Census (2010), 2010 Census. As a result, Vladikavkaz is one of the most populous cities in the North Caucasus region. The city is an Industrial sector, industrial and transport, transportation centre. Manufactured products include processed zinc and lead, machinery, chemical substance, chemicals, clothing and food products. Etymology From 1931 to 1944 and from 1954 to 1990, its name in both Russian and Ossetic languages was ''Ordzhonikidze'' () (after Grigory Ordzhonikidze, Sergo Ordzhonikidze, a Georgian Bolshevik), and from 1944 to 1954 it was officially called ...
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North Ossetia–Alania
The Republic of North Ossetia–Alania; os, Республикӕ Цӕгат Ирыстон — Алани, ''Respublikæ Cægat Iryston — Alani'', ) is a republic of Russia situated in the North Caucasus of Eastern Europe. Its population according to the 2010 Census was 712,980. The republic's capital city is the city of Vladikavkaz, located on the foothills of the Caucasus Mountains. Forming 65.1% of the republic's population as of 2010, the Ossetians are an Iranian ethnic group native to the republic and neighboring South Ossetia. Ossetian is an east Iranian language descended from medieval Alanic and ancient Sarmatian. Unlike many groups in the North Caucasus, Ossetians are predominantly Christians. However, almost 30% of the population adheres to Ossetian ethnic religion, generally called Uatsdin (Уацдин, "True Faith"), and a sizable Muslim minority exists. Ethnic Russians and Ingush, who form a majority in neighboring Ingushetia, form substantial minoritie ...
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France
France (), officially the French Republic ( ), is a country primarily located in Western Europe. It also comprises of Overseas France, overseas regions and territories in the Americas and the Atlantic Ocean, Atlantic, Pacific Ocean, Pacific and Indian Oceans. Its Metropolitan France, metropolitan area extends from the Rhine to the Atlantic Ocean and from the Mediterranean Sea to the English Channel and the North Sea; overseas territories include French Guiana in South America, Saint Pierre and Miquelon in the North Atlantic, the French West Indies, and many islands in Oceania and the Indian Ocean. Due to its several coastal territories, France has the largest exclusive economic zone in the world. France borders Belgium, Luxembourg, Germany, Switzerland, Monaco, Italy, Andorra, and Spain in continental Europe, as well as the Kingdom of the Netherlands, Netherlands, Suriname, and Brazil in the Americas via its overseas territories in French Guiana and Saint Martin (island), ...
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Medicine
Medicine is the science and practice of caring for a patient, managing the diagnosis, prognosis, prevention, treatment, palliation of their injury or disease, and promoting their health. Medicine encompasses a variety of health care practices evolved to maintain and restore health by the prevention and treatment of illness. Contemporary medicine applies biomedical sciences, biomedical research, genetics, and medical technology to diagnose, treat, and prevent injury and disease, typically through pharmaceuticals or surgery, but also through therapies as diverse as psychotherapy, external splints and traction, medical devices, biologics, and ionizing radiation, amongst others. Medicine has been practiced since prehistoric times, and for most of this time it was an art (an area of skill and knowledge), frequently having connections to the religious and philosophical beliefs of local culture. For example, a medicine man would apply herbs and say prayers for healing, o ...
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Blood Transfusion
Blood transfusion is the process of transferring blood products into a person's circulation intravenously. Transfusions are used for various medical conditions to replace lost components of the blood. Early transfusions used whole blood, but modern medical practice commonly uses only components of the blood, such as red blood cells, white blood cells, plasma, clotting factors and platelets. Red blood cells (RBC) contain hemoglobin, and supply the cells of the body with oxygen. White blood cells are not commonly used during transfusion, but they are part of the immune system, and also fight infections. Plasma is the "yellowish" liquid part of blood, which acts as a buffer, and contains proteins and important substances needed for the body's overall health. Platelets are involved in blood clotting, preventing the body from bleeding. Before these components were known, doctors believed that blood was homogeneous. Because of this scientific misunderstanding, many patients died b ...
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Deep Learning
Deep learning (also known as deep structured learning) is part of a broader family of machine learning methods based on artificial neural networks with representation learning. Learning can be supervised, semi-supervised or unsupervised. Deep-learning architectures such as deep neural networks, deep belief networks, deep reinforcement learning, recurrent neural networks, convolutional neural networks and Transformers have been applied to fields including computer vision, speech recognition, natural language processing, machine translation, bioinformatics, drug design, medical image analysis, Climatology, climate science, material inspection and board game programs, where they have produced results comparable to and in some cases surpassing human expert performance. Artificial neural networks (ANNs) were inspired by information processing and distributed communication nodes in biological systems. ANNs have various differences from biological brains. Specifically, artificial ...
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Jean Dausset
Jean-Baptiste-Gabriel-Joachim Dausset (19 October 1916 – 6 June 2009) was a French immunologist born in Toulouse, France. Dausset received the Nobel Prize in Physiology or Medicine in 1980 along with Baruj Benacerraf and George Davis Snell for their discovery and characterisation of the genes making the major histocompatibility complex. Using the money from his Nobel Prize and a grant from the French Television, Dausset founded the Human Polymorphism Study Center ( CEPH) in 1984, which was later renamed the Foundation Jean Dausset-CEPH in his honour. He married Rose Mayoral in 1963, with whom he had two children, Henri and Irène. Jean Dausset died on June 6, 2009 in Majorca, Spain, at the age of 92. Early life Jean-Baptiste-Gabriel-Joachim Dausset was born on 19 October 1916, in Toulouse, France. He was the youngest of four children of Henri Dausset and Elisabeth Dausset (born Renard). His father was from the Pyrénées, and was a doctor by profession, and his mother was a h ...
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Marcel Bessis
Marcel Claude Bessis (15 November 1917 – 28 March 1994) was a French physician known for research on blood cells. Bessis was born in Tunis on 15 November 1917. He was educated at the Lycée Janson-de-Sailly in Paris, France. He developed an interest in microscopy in his teenage years and went on to study medicine at the University of Paris. During the Second World War, he served as a military physician and pioneered the technique of exchange transfusion to treat war injuries. He graduated with a medical degree in 1944. Later he studied exchange transfusion as a treatment for hemolytic disease of the newborn, uremia and acute leukemia. He was a frequent collaborator of Jean Bernard. Bessis used electron microscopy and microcinematography to study the structure and function of blood cells—particularly red blood cells, but also platelets and white blood cells, including the abnormal cells found in leukemia. He invented new instruments to aid his research and developed techniq ...
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Jean Pierre Soulier
Jean Pierre Soulier (14 September 1915 – 18 January 2003) was a French physician and haematologist. He was the General Director of Centre National de Transfusion Sanguine (CNTS) Paris and professor of haematology at the University of Paris , image_name = Coat of arms of the University of Paris.svg , image_size = 150px , caption = Coat of Arms , latin_name = Universitas magistrorum et scholarium Parisiensis , motto = ''Hic et ubique terrarum'' (Latin) , mottoeng = Here and a ..., at the Necker Hospital for Sick Children. References * French hematologists 1915 births 2003 deaths Academic staff of the University of Paris {{France-med-bio-stub ...
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Tzanck Test
In dermatopathology, the Tzanck test, also Tzanck smear, is scraping of an ulcer base to look for Tzanck cells. It is sometimes also called the chickenpox skin test and the herpes skin test. It is a simple, low-cost, and rapid office based test. Tzanck cells (acantholytic cells) are found in: *Herpes simplex * Varicella and herpes zoster *Pemphigus vulgaris *Cytomegalovirus Arnault Tzanck did the first cytological examinations in order to diagnose skin diseases. To diagnose pemphigus, he identified acantholytic cells, and to diagnose of herpetic infections he identified multinucleated giant cells and acantholytic cells. He extended his cytologic findings to certain skin tumors as well. Even though cytological examination can provide rapid and reliable diagnosis for many skin diseases, its use is limited to a few diseases. In endemic regions, Tzanck test is used to diagnose leishmaniasis and leprosy. For other regions, Tzanck test is mainly used to diagnose pemphigus and herpeti ...
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1886 Births
Events January–March * January 1 – Upper Burma is formally annexed to British Burma, following its conquest in the Third Anglo-Burmese War of November 1885. * January 5– 9 – Robert Louis Stevenson's novella ''Strange Case of Dr Jekyll and Mr Hyde'' is published in New York and London. * January 16 – A resolution is passed in the German Parliament to condemn the Prussian deportations, the politically motivated mass expulsion of ethnic Poles and Jews from Prussia, initiated by Otto von Bismarck. * January 18 – Modern field hockey is born with the formation of The Hockey Association in England. * January 29 – Karl Benz patents the first successful gasoline-driven automobile, the Benz Patent-Motorwagen (built in 1885). * February 6– 9 – Seattle riot of 1886: Anti-Chinese sentiments result in riots in Seattle, Washington. * February 8 – The West End Riots following a popular meeting in Trafalgar Square, London. * F ...
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1954 Deaths
Events January * January 1 – The Soviet Union ceases to demand war reparations from West Germany. * January 3 – The Italian broadcaster RAI officially begins transmitting. * January 7 – Georgetown-IBM experiment: The first public demonstration of a machine translation system is held in New York, at the head office of IBM. * January 10 – BOAC Flight 781, a de Havilland Comet jet plane, disintegrates in mid-air due to metal fatigue, and crashes in the Mediterranean near Elba; all 35 people on board are killed. * January 12 – Avalanches in Austria kill more than 200. * January 15 – Mau Mau leader Waruhiu Itote is captured in Kenya. * January 17 – In Yugoslavia, Milovan Đilas, one of the leading members of the League of Communists of Yugoslavia, is relieved of his duties. * January 20 – The US-based National Negro Network is established, with 46 member radio stations. * January 21 – The first nuclear-powered subm ...
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