Antimony Oxychloride
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Antimony Oxychloride
Antimony oxychloride, known since the 15th century, has been known by a plethora of alchemical names. Since the compound functions as both an emetic and a laxative, it was originally used as a purgative. History Its production was first described by Basil Valentine in Currus Triumphalis Antimonii. In 1659 Johann Rudolf Glauber gave a relatively exact chemical interpretation of the reaction. Vittorio Algarotti introduced the substance into medicine, and derivatives of his name (algarot, algoroth) were associated with this compound for many years. The exact composition was unknown for a very long time. The suggestion of SbOCl being a mixture of antimony trichloride and antimony oxide or pure SbOCl were raised. Today the hydrolysis of antimony trichloride is understood; first the SbOCl oxychloride is formed which later forms Sb4O5Cl2. Natural occurrence Neither SbOCl nor the latter compound occur naturally. However, onoratoite is a known Sb-O-Cl mineral, its composition being Sb8 ...
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Nitrosyl Chloride
Nitrosyl chloride is the chemical compound with the formula NOCl. It is a yellow gas that is commonly encountered as a component of aqua regia, a mixture of 3 parts concentrated hydrochloric acid and 1 part of concentrated nitric acid. It is a strong electrophile and oxidizing agent. It is sometimes called Tilden's reagent, after William A. Tilden, who was the first to produce it as a pure compound. Structure and synthesis The molecule is bent. A double bond exists between N and O (distance = 1.16 Å) and a single bond between N and Cl (distance = 1.96 Å). The O=N–Cl angle is 113°. Production Nitrosyl chloride can be produced in many ways. * Combining nitrosylsulfuric acid and HCl affords the compound. This method is used industrially. :HCl + NOHSO4 → H2SO4 + NOCl * A more convenient laboratory method involves the (reversible) dehydration of nitrous acid by HCl : HNO2 + HCl → H2O + NOCl * By the direct combination of chlorine and nitric o ...
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Emetic
Vomiting (also known as emesis and throwing up) is the involuntary, forceful expulsion of the contents of one's stomach through the mouth and sometimes the nose. Vomiting can be the result of ailments like food poisoning, gastroenteritis, pregnancy, motion sickness, or hangover; or it can be an after effect of diseases such as brain tumors, elevated intracranial pressure, or overexposure to ionizing radiation. The feeling that one is about to vomit is called nausea; it often precedes, but does not always lead to vomiting. Impairment due to alcohol or anesthesia can cause inhalation of vomit, leading to suffocation. In severe cases, where dehydration develops, intravenous fluid may be required. Antiemetics are sometimes necessary to suppress nausea and vomiting. Self-induced vomiting can be a component of an eating disorder such as bulimia, and is itself now classified as an eating disorder on its own, purging disorder. Complications Aspiration Vomiting is dangerou ...
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Laxative
Laxatives, purgatives, or aperients are substances that loosen stools and increase bowel movements. They are used to treat and prevent constipation. Laxatives vary as to how they work and the side effects they may have. Certain stimulant, lubricant and saline laxatives are used to evacuate the colon for rectal and bowel examinations, and may be supplemented by enemas under certain circumstances. Sufficiently high doses of laxatives may cause diarrhea. Some laxatives combine more than one active ingredient. Laxatives may be administered orally or rectally. Types Bulk-forming agents Bulk-forming laxatives, also known as roughage, are substances, such as fiber in food and hydrophilic agents in over-the-counter drugs, that add bulk and water to stools so that they can pass more easily through the intestines (lower part of the digestive tract). Properties * Site of action: small and large intestines * Onset of action: 12–72 hours * Examples: dietary fiber, Metamucil, Citru ...
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Basil Valentine
Basil Valentine is the Anglicised version of the name Basilius Valentinus, ostensibly a 15th-century alchemy, alchemist, possibly Canon (priest), Canon of the Benedictine Priory of Saint Peter in Erfurt, Erfurt, Germany but more likely a pseudonym used by one or several 16th-century German authors. According to John Maxson Stillman, who wrote on the history of chemistry, there is no evidence of such a name on the rolls in Germany or Rome and no mention of this name before 1600. His putative history, like his imaginary portrait, appears to be of later creation than the writings themselves. During the 18th century it was suggested that the author of the works attributed to Basil Valentine was Johann Thölde, a salt manufacturer in Germany who lived roughly 1565-1624. Modern scholarship now suggests that one author was Thölde, but that others were involved. Thölde published the first five books under Valentine's name. Whoever he was, Basil Valentine had considerable chemical kn ...
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Johann Rudolf Glauber
Johann Rudolf Glauber (10 March 1604 – 16 March 1670) was a German-Dutch alchemy, alchemist and chemist. Some historians of science have described him as one of the first chemical engineers. His discovery of sodium sulfate in 1625 led to the compound being named after him: "Glauber's salt". Life Born in 1604 in Karlstadt am Main, the son of a barber, he was one of a large family and did not finish school, but is thought to have studied pharmacy and visited laboratories.This section incorporates material from the German Wikipedia and the Galileo Project which are referenced to German sources He said that he was glad that he had not suffered the grind of high school but had instead learned by experience. He lived in Vienna (1625), Salzburg, Giessen, Wertheim am Main, Wertheim (1649–1651), Kitzingen (1651–1655), Basel, Paris, Frankfurt am Main, Cologne and Amsterdam (1640–1644, 1646–1649, 1656-death). He worked first manufacturing mirrors and later for two periods as ...
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Vittorio Algarotti
Vittorio Algarotti (1533-1604), was born in Verona and was president of the Verona College of Medicine from 1593 through his death in 1604. A contemporary of Paracelsus, he introduced the use of antimony oxychloride, which he referred to as ''pulveris angelicus'' (powder of the angels) to medicine.Vittorio Algarotti
Enciclopedia Treccani The ''Enciclopedia Italiana di Scienze, Lettere e Arti'' (Italian for "Italian Encyclopedia of Science, Letters, and Arts"), best known as ''Treccani'' for its developer Giovanni Treccani or ''Enciclopedia Italiana'', is an Italian-language en ...
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Antimony Trichloride
Antimony trichloride is the chemical compound with the formula SbCl3. It is a soft colorless solid with a pungent odor and was known to alchemists as butter of antimony. Preparation Antimony trichloride is prepared by reaction of chlorine with antimony, antimony tribromide, antimony trioxide, or antimony trisulfide. It also may be made by treating antimony trioxide with concentrated hydrochloric acid. Reactions SbCl3 is readily hydrolysed and samples of SbCl3 must be protected from moisture. With a limited amount of water it forms antimony oxychloride releasing hydrogen chloride: :SbCl3 + H2O → SbOCl + 2 HCl With more water it forms which on heating to 460° under argon converts to . SbCl3 readily forms complexes with halides, but the stoichiometries are not a good guide to the composition, for example the contains a chain anion with distorted SbIII octahedra. Similarly the salt contains a polymeric anion of composition with distorted octahedral SbIII. With nitrogen donor ...
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Alchemical Substances
Alchemical studies produced a number of substances, which were later classified as particular chemical compounds or mixtures of compounds. Many of these terms were in common use into the 20th century. Metals and metalloids * Antimony/ – Sb * Bismuth (german: Wismuth) – Bi * Copper/ – associated with Venus. Cu * Gold/ – associated with the Sun. Au * Iron/ – associated with Mars. Fe * Lead/ – associated with Saturn. Pb * Quicksilver/ – associated with Mercury. Hg * Silver/ – associated with the Moon. Ag * Tin/ – associated with Jupiter. Sn Minerals, stones, and pigments * Bluestone – mineral form of copper(II) sulfate pentahydrate, also called blue vitriol. * Borax – sodium borate; was also used to refer to other related minerals. * Cadmia/Tuttia/Tutty – probably zinc carbonate. * Calamine – zinc carbonate. * Calomel/Horn Quicksilver/horn mercury – mercury(I) chloride, a very poisonous purgative formed by subliming a mixture of mercuric chlori ...
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Antimony(III) Compounds
Antimony is a chemical element with the symbol Sb (from la, stibium) and atomic number 51. A lustrous gray metalloid, it is found in nature mainly as the sulfide mineral stibnite (Sb2S3). Antimony compounds have been known since ancient times and were powdered for use as medicine and cosmetics, often known by the Arabic name kohl. The earliest known description of the metal in the West was written in 1540 by Vannoccio Biringuccio. China is the largest producer of antimony and its compounds, with most production coming from the Xikuangshan Mine in Hunan. The industrial methods for refining antimony from stibnite are roasting followed by reduction with carbon, or direct reduction of stibnite with iron. The largest applications for metallic antimony are in alloys with lead and tin, which have improved properties for solders, bullets, and plain bearings. It improves the rigidity of lead-alloy plates in lead–acid batteries. Antimony trioxide is a prominent additive for ...
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Emetics
Vomiting (also known as emesis and throwing up) is the involuntary, forceful expulsion of the contents of one's stomach through the mouth and sometimes the nose. Vomiting can be the result of ailments like food poisoning, gastroenteritis, pregnancy, motion sickness, or hangover; or it can be an after effect of diseases such as brain tumors, elevated intracranial pressure, or overexposure to ionizing radiation. The feeling that one is about to vomit is called nausea; it often precedes, but does not always lead to vomiting. Impairment due to alcohol or anesthesia can cause inhalation of vomit, leading to suffocation. In severe cases, where dehydration develops, intravenous fluid may be required. Antiemetics are sometimes necessary to suppress nausea and vomiting. Self-induced vomiting can be a component of an eating disorder such as bulimia, and is itself now classified as an eating disorder on its own, purging disorder. Complications Aspiration Vomiting is dangerous if g ...
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History Of Pharmacy
The history of pharmacy as an independent science dates back to the first third of the 19th century. Before then, pharmacy evolved from antiquity as part of medicine. The history of pharmacy coincides well with the history of medicine, but it's important that there is a distinction between the two topics. Pharmaceuticals is one of the most-researched fields in the academic industry, but the history surrounding that particular topic is sparse compared to the impact its made world-wide. Before the advent of pharmacists, there existed apothecaries that worked alongside priests and physicians in regard to patient care. Prehistoric Pharmacy Paleopharmacological studies attest to the use of medicinal plants in pre-history. For example, herbs were discovered in the Shanidar Cave, and remains of the areca nut (''Areca catechu)'' in the Spirit Cave. Prehistoric man learned pharmaceutical techniques through instinct, by watching birds and beasts, and using cool water, leaves, dirt, or ...
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