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Anthrax Toxin Protein Key Motif
Anthrax is an infection caused by the bacterium '' Bacillus anthracis''. It can occur in four forms: skin, lungs, intestinal, and injection. Symptom onset occurs between one day and more than two months after the infection is contracted. The skin form presents with a small blister with surrounding swelling that often turns into a painless ulcer with a black center. The inhalation form presents with fever, chest pain and shortness of breath. The intestinal form presents with diarrhea (which may contain blood), abdominal pains, nausea and vomiting. The injection form presents with fever and an abscess at the site of drug injection. According to the USA's Centers for Disease Control and Prevention, the first clinical descriptions of cutaneous anthrax were given by Maret in 1752 and Fournier in 1769. Before that anthrax had been described only through historical accounts. The Prussian scientist Robert Koch (1843–1910) was the first to identify ''Bacillus anthracis'' as the bacte ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Eschar
An eschar (; Greek: ''ἐσχάρᾱ'', ''eskhara''; Latin: ''eschara'') is a slough or piece of dead tissue that is cast off from the surface of the skin, particularly after a burn injury, but also seen in gangrene, ulcer, fungal infections, necrotizing spider bite wounds, tick bites associated with spotted fevers and exposure to cutaneous anthrax. The term ‘eschar’ is not interchangeable with ‘scab’. An eschar contains necrotic tissue whereas a scab is composed of dried blood and exudate. Black eschars are most frequently attributed in medicine to cutaneous anthrax (infection by '' Bacillus anthracis''), which may be contracted through herd animal exposure and also from ''Pasteurella multocida'' exposure in cats and rabbits. A newly identified human rickettsial infection, ''R. parkeri'' rickettsiosis, can be differentiated from Rocky Mountain spotted fever by the presence of an eschar at the site of inoculation. Eschar is sometimes called a ''black wound'' becau ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Doxycycline
Doxycycline is a broad-spectrum tetracycline class antibiotic used in the treatment of infections caused by bacteria and certain parasites. It is used to treat bacterial pneumonia, acne, chlamydia infections, Lyme disease, cholera, typhus, and syphilis. It is also used to prevent malaria in combination with quinine. Doxycycline may be taken by mouth or by injection into a vein. Common side effects include diarrhea, nausea, vomiting, abdominal pain, and an increased risk of sunburn. Use during pregnancy is not recommended. Like other agents of the tetracycline class, it either slows or kills bacteria by inhibiting protein production. It kills malaria by targeting a plastid organelle, the apicoplast. Doxycycline was patented in 1957 and came into commercial use in 1967. It is on the World Health Organization's List of Essential Medicines. Doxycycline is available as a generic medicine. In 2020, it was the 79th most commonly prescribed medication in the United States, with m ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Boil
A boil, also called a furuncle, is a deep folliculitis, which is an infection of the hair follicle. It is most commonly caused by infection by the bacterium ''Staphylococcus aureus'', resulting in a painful swollen area on the skin caused by an accumulation of pus and dead tissue. Boils which are expanded are basically pus-filled nodules. Individual boils clustered together are called carbuncles. Most human infections are caused by coagulase-positive ''S. aureus'' strains, notable for the bacteria's ability to produce coagulase, an enzyme that can clot blood. Almost any organ system can be infected by ''S. aureus''. Signs and symptoms Boils are bumpy, red, pus-filled lumps around a hair follicle that are tender, warm, and painful. They range from pea-sized to golf ball-sized. A yellow or white point at the center of the lump can be seen when the boil is ready to drain or discharge pus. In a severe infection, an individual may experience fever, swollen lymph nodes, and fatig ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cutaneous Anthrax Lesion On The Neck
Skin is the layer of usually soft, flexible outer tissue covering the body of a vertebrate animal, with three main functions: protection, regulation, and sensation. Other animal coverings, such as the arthropod exoskeleton, have different developmental origin, structure and chemical composition. The adjective cutaneous means "of the skin" (from Latin ''cutis'' 'skin'). In mammals, the skin is an organ of the integumentary system made up of multiple layers of ectodermal tissue and guards the underlying muscles, bones, ligaments, and internal organs. Skin of a different nature exists in amphibians, reptiles, and birds. Skin (including cutaneous and subcutaneous tissues) plays crucial roles in formation, structure, and function of extraskeletal apparatus such as horns of bovids (e.g., cattle) and rhinos, cervids' antlers, giraffids' ossicones, armadillos' osteoderm, and os penis/os clitoris. All mammals have some hair on their skin, even marine mammals like whales, dolph ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Skin Reaction To Anthrax
Skin is the layer of usually soft, flexible outer tissue covering the body of a vertebrate animal, with three main functions: protection, regulation, and sensation. Other animal coverings, such as the arthropod exoskeleton, have different developmental origin, structure and chemical composition. The adjective cutaneous means "of the skin" (from Latin ''cutis'' 'skin'). In mammals, the skin is an organ of the integumentary system made up of multiple layers of ectodermal tissue and guards the underlying muscles, bones, ligaments, and internal organs. Skin of a different nature exists in amphibians, reptiles, and birds. Skin (including cutaneous and subcutaneous tissues) plays crucial roles in formation, structure, and function of extraskeletal apparatus such as horns of bovids (e.g., cattle) and rhinos, cervids' antlers, giraffids' ossicones, armadillos' osteoderm, and os penis/os clitoris. All mammals have some hair on their skin, even marine mammals like whales, dolphins, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bradford
Bradford is a city and the administrative centre of the City of Bradford district in West Yorkshire, England. The city is in the Pennines' eastern foothills on the banks of the Bradford Beck. Bradford had a population of 349,561 at the 2011 census; the second-largest population centre in the county after Leeds, which is to the east of the city. It shares a continuous built-up area with the towns of Shipley, Silsden, Bingley and Keighley in the district as well as with the metropolitan county's other districts. Its name is also given to Bradford Beck. It became a West Riding of Yorkshire municipal borough in 1847 and received its city charter in 1897. Since local government reform in 1974, the city is the administrative centre of a wider metropolitan district, city hall is the meeting place of Bradford City Council. The district has civil parishes and unparished areas and had a population of , making it the most populous district in England. In the century leadin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cumberland County, New South Wales
Cumberland County is a county in the State of New South Wales, Australia. Most of the Sydney metropolitan area is located within the County of Cumberland. The County of Cumberland stretches from Broken Bay to the north, the Hawkesbury River to the north-west, the Nepean River to the west, the Cataract River to the south-west and the northern suburbs of Wollongong to the south. It includes the area of the Cumberland Plain. History The name ''Cumberland'' was conferred by Governor Arthur Phillip in honour of Prince Henry Duke of Cumberland and Strathearn at a gathering to celebrate the birthday of his brother, King George III, on 4 June 1788. The county has been marked on maps since the start of the colony, as shown along the key on 1789 mapdescribing Port Jackson as being within the county of Cumberland. In the nineteenth century, parts of the county were in the South and North Riding electoral districts from 1856 to 1859, which were replaced by Central Cumberland. The ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bartholomaeus Anglicus
Bartholomaeus Anglicus (before 1203–1272), also known as Bartholomew the Englishman and Berthelet, was an early 13th-century Scholastic of Paris, a member of the Franciscan order. He was the author of the compendium ''De proprietatibus rerum'' ("On the Properties of Things"), dated c.1240, an early forerunner of the encyclopedia and a widely cited book in the Middle Ages. Bartholomew also held senior positions within the church and was appointed Bishop of Łuków in what is now Poland, although he was not consecrated to that position. Early life Little is known of Bartholomew's early life. He is believed to have been born around the turn of the 13th century to unknown parents. The first record of him was in 1224 in Paris as a teacher, although he is also believed to have studied at Oxford University. Encyclopedia The work ''De proprietatibus rerum'' was written at the school of Magdeburg in Saxonia and intended for the use of students and the general public. Bartholomew ca ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lesion
A lesion is any damage or abnormal change in the tissue of an organism, usually caused by disease or trauma. ''Lesion'' is derived from the Latin "injury". Lesions may occur in plants as well as animals. Types There is no designated classification or naming convention for lesions. Since lesions can occur anywhere in the body and the definition of a lesion is so broad, the varieties of lesions are virtually endless. Generally, lesions may be classified by their patterns, their sizes, their locations, or their causes. They can also be named after the person who discovered them. For example, Ghon lesions, which are found in the lungs of those with tuberculosis, are named after the lesion's discoverer, Anton Ghon. The characteristic skin lesions of a varicella zoster virus infection are called '' chickenpox''. Lesions of the teeth are usually called dental caries. Location Lesions are often classified by their tissue types or locations. For example, a "skin lesion" or a " bra ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Egyptian Language
The Egyptian language or Ancient Egyptian ( ) is a dead language, dead Afroasiatic languages, Afro-Asiatic language that was spoken in ancient Egypt. It is known today from a large Text corpus, corpus of surviving texts which were made accessible to the modern world following the decipherment of ancient Egyptian scripts, decipherment of the ancient Egyptian scripts in the early 19th century. Egyptian is one of the List of languages by first written accounts, earliest written languages, first being recorded in the Egyptian hieroglyphs, hieroglyphic script in the late 4th millennium BC. It is also the longest-attested human language, with a written record spanning over 4000 years. Its classical language, classical form is known as Middle Egyptian, the vernacular of the Middle Kingdom of Egypt which remained the literary language of Egypt until the Egypt (Roman province), Roman period. By the time of classical antiquity the spoken language had evolved into Demotic (Egyptian), Dem ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Greek Language
Greek ( el, label=Modern Greek, Ελληνικά, Elliniká, ; grc, Ἑλληνική, Hellēnikḗ) is an independent branch of the Indo-European family of languages, native to Greece, Cyprus, southern Italy (Calabria and Salento), southern Albania, and other regions of the Balkans, the Black Sea coast, Asia Minor, and the Eastern Mediterranean. It has the longest documented history of any Indo-European language, spanning at least 3,400 years of written records. Its writing system is the Greek alphabet, which has been used for approximately 2,800 years; previously, Greek was recorded in writing systems such as Linear B and the Cypriot syllabary. The alphabet arose from the Phoenician script and was in turn the basis of the Latin, Cyrillic, Armenian, Coptic, Gothic, and many other writing systems. The Greek language holds a very important place in the history of the Western world. Beginning with the epics of Homer, ancient Greek literature includes many works of lasting impo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Anthrax Weaponization
Anthrax weaponization is the development and deployment of the bacterium '' Bacillus anthracis'' or, more commonly, its spore (referred to as anthrax), as a biological weapon. As a biological weapon, anthrax has been used in biowarfare and bioterrorism since 1914. However, in 1975 the Biological Weapons Convention prohibited the "development, production and stockpiling" of biological weapons. It has since been used in bioterrorism. Anthrax spores can cause infection from inhalation, skin contact, ingestion or injection and when untreated can lead to death. Likely delivery methods of weaponized anthrax include aerial dispersal or dispersal through livestock, notable bioterrorism uses include the 2001 anthrax attacks and an incident in 1993 by the Aum Shinrikyo group in Japan. Biological overview Concentrated anthrax spores, and not necessarily the bacterium '' Bacillus anthracis'', pose the biggest risk as a biological weapons to humans. When airborne, anthrax spores are not e ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
