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Annemarie Weber
Annemarie Weber (11 September 1923 – 5 July 2012) was a German-born American physiologist who studied the biochemistry of muscle action. She was the daughter of the German physiologist Hans Hermann Weber who also studied muscle structure and function. Weber was born in Tübingen where her father worked at the university and grew up in Königsberg. Her brother Jürgen Weber (1928–2007) became a sculptor. She was often separated from family during World War II. She joined the University of Tübingen and received an MD in 1950 and then studied myosin ATPase for her doctorate. She received a Rockefeller foundation grant and spent her postdoctoral at University College London with Archibald Hill, A.V. Hill and at Harvard. She also trained under her father who had friends around the world including Albert Szent-Györgyi who had moved to the United States. She first went to Columbia University as a research associate in 1954 and became a lecturer in 1959. She became a professor at St. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hans Hermann Weber
Hans Hermann Julius Wilhelm Weber (17 June 1896 – 12 June 1974) was a German physiologist and biochemist who worked on muscle structure and function. He was among the pioneers who helped establish the mechanism of muscle relaxation and contraction. His daughter Annemarie Weber also continued work in myosin biochemistry. Weber was born in Berlin, son of physician Hermann Weber and Annemarie Becher. He studied at the Kaiserin Augusta Gymnasium, Mommsen Gymnasium in Berlin and in 1914 he was conscripted and continued in military service until 1919 although he was wounded in 1916, allowing him to study medicine for a semester. After 1919 he continued his studies at Greifswald, Rostock and Heidelberg. His doctoral dissertation was under Hans Winterstein at Rostock and examined the role of lactic acid in rigor mortis induction. He received an MD in 1921 and worked in the laboratory of Otto Fritz Meyerhof, Otto Meyerhof at Kiel with a focus on muscle energetics. In 1922 he moved to Rosto ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tübingen
Tübingen (, , Swabian: ''Dibenga'') is a traditional university city in central Baden-Württemberg, Germany. It is situated south of the state capital, Stuttgart, and developed on both sides of the Neckar and Ammer rivers. about one in three of the 90,000 people living in Tübingen is a student. As of the 2018/2019 winter semester, 27,665 students attend the Eberhard Karls University of Tübingen. The city has the lowest median age in Germany, in part due to its status as a university city. As of December 31, 2015, the average age of a citizen of Tübingen is 39.1 years. The city is known for its veganism and environmentalism. Immediately north of the city lies the Schönbuch, a densely wooded nature park. The Swabian Alb mountains rise about (beeline Tübingen City to Roßberg - 869 m) to the southeast of Tübingen. The Ammer and Steinlach rivers are tributaries of the Neckar river, which flows in an easterly direction through the city, just south of the medieval old t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
World War II
World War II or the Second World War, often abbreviated as WWII or WW2, was a world war that lasted from 1939 to 1945. It involved the vast majority of the world's countries—including all of the great powers—forming two opposing military alliances: the Allies and the Axis powers. World War II was a total war that directly involved more than 100 million personnel from more than 30 countries. The major participants in the war threw their entire economic, industrial, and scientific capabilities behind the war effort, blurring the distinction between civilian and military resources. Aircraft played a major role in the conflict, enabling the strategic bombing of population centres and deploying the only two nuclear weapons ever used in war. World War II was by far the deadliest conflict in human history; it resulted in 70 to 85 million fatalities, mostly among civilians. Tens of millions died due to genocides (including the Holocaust), starvation, ma ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Tübingen
The University of Tübingen, officially the Eberhard Karl University of Tübingen (german: Eberhard Karls Universität Tübingen; la, Universitas Eberhardina Carolina), is a public research university located in the city of Tübingen, Baden-Württemberg, Germany. The University of Tübingen is one of eleven German Excellence Universities. The University of Tübingen is especially known as a centre for the study of plant biology, medicine, law, archeology, ancient cultures, philosophy, theology, and religious studies as well as more recently as center of excellence for artificial intelligence. The university's noted alumni include presidents, EU Commissioners, and judges of the Federal Constitutional Court. The university is associated with eleven Nobel laureates, especially in the fields of medicine and chemistry. History The University of Tübingen was founded in 1477 by Count Eberhard V (Eberhard im Bart, 1445–1496), later the first Duke of Württemberg, a civic and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Myosin
Myosins () are a superfamily of motor proteins best known for their roles in muscle contraction and in a wide range of other motility processes in eukaryotes. They are ATP-dependent and responsible for actin-based motility. The first myosin (M2) to be discovered was in 1864 by Wilhelm Kühne. Kühne had extracted a viscous protein from skeletal muscle that he held responsible for keeping the tension state in muscle. He called this protein ''myosin''. The term has been extended to include a group of similar ATPases found in the cells of both striated muscle tissue and smooth muscle tissue. Following the discovery in 1973 of enzymes with myosin-like function in '' Acanthamoeba castellanii'', a global range of divergent myosin genes have been discovered throughout the realm of eukaryotes. Although myosin was originally thought to be restricted to muscle cells (hence '' myo-''(s) + '' -in''), there is no single "myosin"; rather it is a very large superfamily of genes whose p ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University College London
, mottoeng = Let all come who by merit deserve the most reward , established = , type = Public research university , endowment = £143 million (2020) , budget = £1.544 billion (2019/20) , chancellor = Anne, Princess Royal(as Chancellor of the University of London) , provost = Michael Spence , head_label = Chair of the council , head = Victor L. L. Chu , free_label = Visitor , free = Sir Geoffrey Vos , academic_staff = 9,100 (2020/21) , administrative_staff = 5,855 (2020/21) , students = () , undergrad = () , postgrad = () , coordinates = , campus = Urban , city = London, England , affiliations = , colours = Purple and blue celeste , nickname ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Archibald Hill
Archibald Vivian Hill (26 September 1886 – 3 June 1977), known as A. V. Hill, was a British physiologist, one of the founders of the diverse disciplines of biophysics and operations research. He shared the 1922 Nobel Prize in Physiology or Medicine for his elucidation of the production of heat and mechanical work in muscles. Biography Born in Bristol, he was educated at Blundell's School and graduated from Trinity College, Cambridge as third wrangler in the mathematics tripos before turning to physiology. While still an undergraduate at Trinity College, he derived in 1909 what came to be known as the Langmuir equation. This is closely related to Michaelis-Menten kinetics. In this paper, Hill's first publication, he derived both the equilibrium form of the Langmuir equation, and also the exponential approach to equilibrium. The paper, written under the supervision of John Newport Langley, is a landmark in the history of receptor theory, because the context for the derivatio ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Albert Szent-Györgyi
Albert Imre Szent-Györgyi de Nagyrápolt ( hu, nagyrápolti Szent-Györgyi Albert Imre; September 16, 1893 – October 22, 1986) was a Hungarian biochemist who won the Nobel Prize in Physiology or Medicine in 1937. He is credited with first isolating vitamin C and discovering the components and reactions of the citric acid cycle. He was also active in the Hungarian Resistance during World War II, and entered Hungarian politics after the war. Early life Szent-Györgyi was born in Budapest, Kingdom of Hungary in 1893. His father, Miklós Szent-Györgyi, was a landowner, born in Marosvásárhely, Transylvania (today Târgu Mureş, Romania), a Calvinist, and could trace his ancestry back to 1608 when Sámuel, a Calvinist predicant, was ennobled. At the time of Szent-Györgyi's birth, being of the nobility was considered important and created opportunities that otherwise were not available. (Miklós Szent-Györgyi's parents were Imre Szent-Györgyi and Mária Csiky). His mot ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Columbia University
Columbia University (also known as Columbia, and officially as Columbia University in the City of New York) is a private research university in New York City. Established in 1754 as King's College on the grounds of Trinity Church in Manhattan, Columbia is the oldest institution of higher education in New York and the fifth-oldest institution of higher learning in the United States. It is one of nine colonial colleges founded prior to the Declaration of Independence. It is a member of the Ivy League. Columbia is ranked among the top universities in the world. Columbia was established by royal charter under George II of Great Britain. It was renamed Columbia College in 1784 following the American Revolution, and in 1787 was placed under a private board of trustees headed by former students Alexander Hamilton and John Jay. In 1896, the campus was moved to its current location in Morningside Heights and renamed Columbia University. Columbia scientists and scholars have ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Pennsylvania
The University of Pennsylvania (also known as Penn or UPenn) is a private research university in Philadelphia. It is the fourth-oldest institution of higher education in the United States and is ranked among the highest-regarded universities by numerous organizations and scholars. While the university dates its founding to 1740, it was created by Benjamin Franklin and other Philadelphia citizens in 1749. It is a member of the Ivy League. The university has four undergraduate schools as well as twelve graduate and professional schools. Schools enrolling undergraduates include the College of Arts and Sciences, the School of Engineering and Applied Science, the Wharton School, and the School of Nursing. Among its highly ranked graduate schools are its law school, whose first professor wrote the first draft of the United States Constitution, its medical school, the first in North America, and Wharton, the first collegiate business school. Penn's endowment is US$20.7 billio ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Actin
Actin is a family of globular multi-functional proteins that form microfilaments in the cytoskeleton, and the thin filaments in muscle fibrils. It is found in essentially all eukaryotic cells, where it may be present at a concentration of over 100 μM; its mass is roughly 42 kDa, with a diameter of 4 to 7 nm. An actin protein is the monomeric subunit of two types of filaments in cells: microfilaments, one of the three major components of the cytoskeleton, and thin filaments, part of the contractile apparatus in muscle cells. It can be present as either a free monomer called G-actin (globular) or as part of a linear polymer microfilament called F-actin (filamentous), both of which are essential for such important cellular functions as the mobility and contraction of cells during cell division. Actin participates in many important cellular processes, including muscle contraction, cell motility, cell division and cytokinesis, vesicle and organelle movement, cell sign ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1923 Births
Nineteen or 19 may refer to: * 19 (number), the natural number following 18 and preceding 20 * one of the years 19 BC, AD 19, 1919, 2019 Films * ''19'' (film), a 2001 Japanese film * ''Nineteen'' (film), a 1987 science fiction film Music * 19 (band), a Japanese pop music duo Albums * ''19'' (Adele album), 2008 * ''19'', a 2003 album by Alsou * ''19'', a 2006 album by Evan Yo * ''19'', a 2018 album by MHD * ''19'', one half of the double album ''63/19'' by Kool A.D. * ''Number Nineteen'', a 1971 album by American jazz pianist Mal Waldron * ''XIX'' (EP), a 2019 EP by 1the9 Songs * "19" (song), a 1985 song by British musician Paul Hardcastle. * "Nineteen", a song by Bad4Good from the 1992 album '' Refugee'' * "Nineteen", a song by Karma to Burn from the 2001 album ''Almost Heathen''. * "Nineteen" (song), a 2007 song by American singer Billy Ray Cyrus. * "Nineteen", a song by Tegan and Sara from the 2007 album '' The Con''. * "XIX" (song), a 2014 song by Slipk ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
