Ann Harrison (lung Transplant Recipient)
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Ann Harrison (lung Transplant Recipient)
Ann Harrison (September 24, 1944 – April 20, 2001) was the recipient of the world's first successful human double lung transplant. She survived for almost fifteen years after the surgery and died of unrelated causes. Operation Harrison suffered from end-stage emphysema and thoracic surgeon Joel D. Cooper had told her that without surgery, she had only a few months to live. The operation was performed at Toronto General Hospital on November 26, 1986, when she received the lungs of an 18-year-old Kingston, Ontario, native who had recently died in a car accident. Cooper had previously successfully performed a single lung transplant on pulmonary fibrosis victim Tom Hall on November 7, 1983, but this was the first successful double lung transplant. Death Ann Harrison died aged 56 at Toronto General Hospital on April 20, 2001, of a brain aneurysm unrelated to her operation.
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Lung Transplantation
Lung transplantation, or pulmonary transplantation, is a surgical procedure in which one or both lungs are replaced by lungs from a donor. Donor lungs can be retrieved from a living or deceased donor. A living donor can only donate one lung lobe. With some lung diseases, a recipient may only need to receive a single lung. With other lung diseases such as cystic fibrosis, it is imperative that a recipient receive two lungs. While lung transplants carry certain associated risks, they can also extend life expectancy and enhance the quality of life for those with end stage pulmonary disease. Qualifying conditions Lung transplantation is the therapeutic measure of last resort for patients with end-stage lung disease who have exhausted all other available treatments without improvement. A variety of conditions may make such surgery necessary. As of 2005, the most common reasons for lung transplantation in the United States were: * 27% chronic obstructive pulmonary disease (COPD), inclu ...
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Cystic Fibrosis
Cystic fibrosis (CF) is a rare genetic disorder that affects mostly the lungs, but also the pancreas, liver, kidneys, and intestine. Long-term issues include difficulty breathing and coughing up mucus as a result of frequent lung infections. Other signs and symptoms may include sinus infections, poor growth, fatty stool, clubbing of the fingers and toes, and infertility in most males. Different people may have different degrees of symptoms. Cystic fibrosis is inherited in an autosomal recessive manner. It is caused by the presence of mutations in both copies of the gene for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. Those with a single working copy are carriers and otherwise mostly healthy. CFTR is involved in the production of sweat, digestive fluids, and mucus. When the CFTR is not functional, secretions which are usually thin instead become thick. The condition is diagnosed by a sweat test and genetic testing. Screening of infants at bi ...
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People From Toronto
This is a list of notable people who are from Toronto, Ontario, or have spent a large part or formative part of their career in that city. A * Abdominal – hip hop musician * Patrick J. Adams – actor ('' Suits'') * Oluniké Adeliyi – actress ('' Flashpoint'') * Chris Alexander diplomat * Robbie Amell – actor * Stephen Amell – actor (''Arrow'') * Enza Anderson – writer, transgender rights activist * Shamier Anderson – actor * Gordon Stewart Anderson – author * John Andrews – architect * Mark Andrews – swimmer * Lou Angotti – former NHL player * Kent Angus – businessman * Steve Anthony – television host * Danny Antonucci – animator and creator of ''Ed, Edd n Eddy'' * Andreas Apostolopoulos – businessman * Alfred Apps – businessman, lawyer and political activist * Syl Apps – former NHL player * Will Arnett – actor * Amy Ashmore Clark – vaudeville performer, songwriter, composer * Margaret Atwood – Booker Prize-winning novelist, poe ...
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2001 Deaths
This is a list of deaths of notable people, organised by year. New deaths articles are added to their respective month (e.g., Deaths in ) and then linked here. 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 1999 1998 1997 1996 1995 1994 1993 1992 1991 1990 1989 1988 1987 See also * Lists of deaths by day The following pages, corresponding to the Gregorian calendar, list the historical events, births, deaths, and holidays and observances of the specified day of the year: Footnotes See also * Leap year * List of calendars * List of non-standard ... * Deaths by year {{DEFAULTSORT:deaths by year ...
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1944 Births
Events Below, the events of World War II have the "WWII" prefix. January * January 2 – WWII: ** Free France, Free French General Jean de Lattre de Tassigny is appointed to command First Army (France), French Army B, part of the Sixth United States Army Group in North Africa. ** Landing at Saidor: 13,000 US and Australian troops land on Papua New Guinea, in an attempt to cut off a Japanese retreat. * January 8 – WWII: Philippine Commonwealth troops enter the province of Ilocos Sur in northern Luzon and attack Japanese forces. * January 11 ** President of the United States Franklin D. Roosevelt proposes a Second Bill of Rights for social and economic security, in his State of the Union address. ** The Nazi German administration expands Kraków-Płaszów concentration camp into the larger standalone ''Konzentrationslager Plaszow bei Krakau'' in occupied Poland. * January 12 – WWII: Winston Churchill and Charles de Gaulle begin a 2-day conference in Marrakech ...
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Eulogy
A eulogy (from , ''eulogia'', Classical Greek, ''eu'' for "well" or "true", ''logia'' for "words" or "text", together for "praise") is a speech or writing in praise of a person or persons, especially one who recently died or retired, or as a term of endearment. Eulogies may be given as part of funeral services. In the US, they take place in a funeral home during or after a wake; in the UK, they are said during the service, typically at a crematorium or place of worship, before the wake. In the US, some denominations either discourage or do not permit eulogies at services to maintain respect for traditions. Eulogies can also praise people who are still alive. This normally takes place on special occasions like birthdays, office parties, retirement celebrations, etc. Eulogies should not be confused with elegies, which are poems written in tribute to the dead; nor with obituaries, which are published biographies recounting the lives of those who have recently died; nor with obs ...
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Star-News
''Star-News'' is an American, English language daily newspaper for Wilmington, North Carolina, and its surrounding area (known as the Lower Cape Fear). It is North Carolina's oldest newspaper in continuous publication. It was owned by Halifax Media Group until 2015, when Halifax was acquired by New Media Investment Group. The ''Star-News'' has a circulation of 41,300 daily (47,400 Sunday) and covers a three-county region in Southeastern North Carolina: New Hanover, Brunswick and Pender. History The paper was originally published on September 23, 1867, as the ''Wilmington Evening Star'' by former Confederate Major William H. Bernard. Shortly after first publishing the paper, Bernard changed the paper to come out in the morning and changed the paper name to the ''Wilmington Morning Star''. " was an ardent advocacy of white supremacy-a view never more strongly demonstrated than in its coverage of the Wilmington race riots of 1898." In 1927, R. W. Page bought the ''Morning S ...
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Wilmington, North Carolina
Wilmington is a port city in and the county seat of New Hanover County in coastal southeastern North Carolina, United States. With a population of 115,451 at the 2020 census, it is the eighth most populous city in the state. Wilmington is the principal city of the Wilmington Metropolitan Statistical Area, a metropolitan area that includes New Hanover and Pender counties in southeastern North Carolina, which had a population of 301,284 at the 2020 census. Its historic downtown has a Riverwalk, developed as a tourist attraction in the late 20th century. In 2014, Wilmington's riverfront was ranked as the "Best American Riverfront" by readers of ''USA Today''. The National Trust for Historic Preservation selected Wilmington as one of its 2008 Dozen Distinctive Destinations. City residents live between the Cape Fear river and the Atlantic ocean, with four nearby beach communities just outside Wilmington: Fort Fisher, Wrightsville Beach, Carolina Beach and Kure Beach, all wi ...
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Canadian Medical Association Journal
The ''Canadian Medical Association Journal'' (French ''Journal de l'Association Médicale Canadienne'') is a peer-reviewed general medical journal published by the Canadian Medical Association (CMA). It publishes original clinical research, analyses and reviews, news, practice updates, and editorials. Notable articles The journal has published the following notable articles: # Banting and Best's 1922 report, "Pancreatic extracts in the treatment of diabetes mellitus". Banting and Macleod were awarded a Nobel Prize for the discovery of insulin in 1923.; Reprinted as # 1926 – the first use of liver as a treatment for anemia, which led to the isolation of vitamin B12. # 1938 – CMAJ warns about the relationship between sun exposure and skin cancer. # 2003 – CMAJ responds rapidly to SARS (severe acute respiratory syndrome), publishing timely information during the outbreak. # 2009 – CMAJ publishes a research paper on the increased risk of reinfarction associated with proton ...
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Emphysema
Emphysema, or pulmonary emphysema, is a lower respiratory tract disease, characterised by air-filled spaces ( pneumatoses) in the lungs, that can vary in size and may be very large. The spaces are caused by the breakdown of the walls of the alveoli and they replace the spongy lung parenchyma. This reduces the total alveolar surface available for gas exchange leading to a reduction in oxygen supply for the blood. Emphysema usually affects the middle aged or older population because it takes time to develop with the effects of tobacco smoking, and other risk factors. Alpha-1 antitrypsin deficiency is a genetic risk factor that may lead to the condition presenting earlier. When associated with significant airflow limitation, emphysema is a major subtype of chronic obstructive pulmonary disease (COPD), a progressive lung disease characterized by long-term breathing problems and poor airflow. Without COPD, the finding of emphysema on a CT lung scan still confers a higher mortality r ...
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Brain Aneurysm
An intracranial aneurysm, also known as a brain aneurysm, is a cerebrovascular disorder in which weakness in the wall of a cerebral artery or vein causes a localized dilation or ballooning of the blood vessel. Aneurysms in the posterior circulation (basilar artery, vertebral arteries and posterior communicating artery) have a higher risk of rupture. Basilar artery aneurysms represent only 3–5% of all intracranial aneurysms but are the most common aneurysms in the posterior circulation. Classification Cerebral aneurysms are classified both by size and shape. Small aneurysms have a diameter of less than 15 mm. Larger aneurysms include those classified as large (15 to 25 mm), giant (25 to 50 mm), and super-giant (over 50 mm). Berry (saccular) aneurysms Saccular aneurysms, also known as berry aneurysms, appear as a round outpouching and are the most common form of cerebral aneurysm. Causes include connective tissue disorders, polycystic kidney disease, art ...
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Pulmonary Fibrosis
Pulmonary fibrosis is a condition in which the lungs become scarred over time. Symptoms include shortness of breath, a dry cough, feeling tired, weight loss, and nail clubbing. Complications may include pulmonary hypertension, respiratory failure, pneumothorax, and lung cancer. Causes include environmental pollution, certain medications, connective tissue diseases, infections, and interstitial lung diseases. Idiopathic pulmonary fibrosis (IPF), an interstitial lung disease of unknown cause, is most common. Diagnosis may be based on symptoms, medical imaging, lung biopsy, and lung function tests. There is no cure and there are limited treatment options available. Treatment is directed towards efforts to improve symptoms and may include oxygen therapy and pulmonary rehabilitation. Certain medications may be used to try to slow the worsening of scarring. Lung transplantation may occasionally be an option. At least 5 million people are affected globally. Life expectancy is gener ...
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