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Ann E. Weber
Ann E. Weber is the Senior Vice President for Drug Discovery at Kallyope Inc. in New York City. She previously worked with Merck Research Laboratories (MRL), joining the company in 1987 and retiring from the position of Vice President for Lead Optimization Chemistry in 2015. She has helped develop more than 40 drug candidates including FDA-approved treatments for Type 2 diabetes. She has received a number of awards, including the Perkin Medal (2017) and has been inducted into the ACS Division of Medicinal Chemistry’s MEDI Hall of Fame. Education Weber grew up in Oshkosh, Wisconsin, the child of a nurse and a doctor. There she attended Lourdes High School (Oshkosh, Wisconsin), a Catholic school. Weber earned a B.S. degree in chemistry summa cum laude from the University of Notre Dame (1982) and a Ph.D. degree from Harvard University, where she studied synthetic organic chemistry with David A. Evans. She was the first woman to receive a Ph.D. from his group, in 1987. Research W ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Merck Research Laboratories
Merck & Co., Inc. is an American multinational pharmaceutical company headquartered in Rahway, New Jersey, and is named for Merck Group, founded in Germany in 1668, of whom it was once the American arm. The company does business as Merck Sharp & Dohme or MSD outside the United States and Canada. Merck & Co. was originally established as the American affiliate of Merck Group in 1891. Merck develops and produces medicines, vaccines, biologic therapies and animal health products. It has multiple blockbuster drugs or products each with 2020 revenues including cancer immunotherapy, anti-diabetic medication and vaccines against HPV and chickenpox. The company is ranked 71st on the 2022 ''Fortune'' 500 and 87th on the 2022 ''Forbes'' Global 2000, both based on 2021 revenues. Products The company develops medicines, vaccines, biologic therapies and animal health products. In 2020, the company had 6 blockbuster drugs or products, each with over $1 billion in revenue: ''Keytruda'' (p ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Urinary Incontinence
Urinary incontinence (UI), also known as involuntary urination, is any uncontrolled leakage of urine. It is a common and distressing problem, which may have a large impact on quality of life. It has been identified as an important issue in geriatric health care. The term enuresis is often used to refer to urinary incontinence primarily in children, such as nocturnal enuresis (bed wetting). UI is an example of a stigmatized medical condition, which creates barriers to successful management and makes the problem worse. People may be too embarrassed to seek medical help, and attempt to self-manage the symptom in secrecy from others. Pelvic surgery, pregnancy, childbirth, and menopause are major risk factors. Urinary incontinence is often a result of an underlying medical condition but is under-reported to medical practitioners. There are four main types of incontinence: * Urge incontinence due to an overactive bladder * Stress incontinence due to "a poorly functioning urethral sph ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Women Chemists
American(s) may refer to: * American, something of, from, or related to the United States of America, commonly known as the "United States" or "America" ** Americans, citizens and nationals of the United States of America ** American ancestry, people who self-identify their ancestry as "American" ** American English, the set of varieties of the English language native to the United States ** Native Americans in the United States, indigenous peoples of the United States * American, something of, from, or related to the Americas, also known as "America" ** Indigenous peoples of the Americas * American (word), for analysis and history of the meanings in various contexts Organizations * American Airlines, U.S.-based airline headquartered in Fort Worth, Texas * American Athletic Conference, an American college athletic conference * American Recordings (record label), a record label previously known as Def American * American University, in Washington, D.C. Sports teams Soccer * B ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
21st-century American Chemists
The 1st century was the century spanning AD 1 ( I) through AD 100 ( C) according to the Julian calendar. It is often written as the or to distinguish it from the 1st century BC (or BCE) which preceded it. The 1st century is considered part of the Classical era, epoch, or historical period. The 1st century also saw the appearance of Christianity. During this period, Europe, North Africa and the Near East fell under increasing domination by the Roman Empire, which continued expanding, most notably conquering Britain under the emperor Claudius ( AD 43). The reforms introduced by Augustus during his long reign stabilized the empire after the turmoil of the previous century's civil wars. Later in the century the Julio-Claudian dynasty, which had been founded by Augustus, came to an end with the suicide of Nero in AD 68. There followed the famous Year of Four Emperors, a brief period of civil war and instability, which was finally brought to an end by Vespasian, ninth Roman em ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Harvard Graduate School Of Arts And Sciences Alumni
Harvard University is a private Ivy League research university in Cambridge, Massachusetts. Founded in 1636 as Harvard College and named for its first benefactor, the Puritan clergyman John Harvard, it is the oldest institution of higher learning in the United States and one of the most prestigious and highly ranked universities in the world. The university is composed of ten academic faculties plus Harvard Radcliffe Institute. The Faculty of Arts and Sciences offers study in a wide range of undergraduate and graduate academic disciplines, and other faculties offer only graduate degrees, including professional degrees. Harvard has three main campuses: the Cambridge campus centered on Harvard Yard; an adjoining campus immediately across Charles River in the Allston neighborhood of Boston; and the medical campus in Boston's Longwood Medical Area. Harvard's endowment is valued at $50.9 billion, making it the wealthiest academic institution in the world. Endowment inco ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Notre Dame College Of Arts And Letters Alumni
Notre may refer to: *Notre language *André Le Nôtre André Le Nôtre (; 12 March 1613 – 15 September 1700), originally rendered as André Le Nostre, was a French landscape architect and the principal gardener of King Louis XIV of France. He was the landscape architect who designed the gar ... * See also * Notre Dame (other) {{dab ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Living People
Related categories * :Year of birth missing (living people) / :Year of birth unknown * :Date of birth missing (living people) / :Date of birth unknown * :Place of birth missing (living people) / :Place of birth unknown * :Year of death missing / :Year of death unknown * :Date of death missing / :Date of death unknown * :Place of death missing / :Place of death unknown * :Missing middle or first names See also * :Dead people * :Template:L, which generates this category or death years, and birth year and sort keys. : {{DEFAULTSORT:Living people 21st-century people People by status ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sylvia M
Sylvia may refer to: People *Sylvia (given name) *Sylvia (singer), American country music and country pop singer and songwriter *Sylvia Robinson, American singer, record producer, and record label executive * Sylvia Vrethammar, Swedish singer credited as "Sylvia" in Australia and the UK * Tim Sylvia, American mixed martial arts fighter * Colin Sylvia, Australian football player Places * Mount Sylvia, a former name of Xueshan on Taiwan Island *Mount Sylvia, Queensland, Australia * Sylvia, Kansas, a town in Kansas, United States * Sylvia's Restaurant of Harlem, New York City, New York, United States Art, entertainment, and media Comics * ''Sylvia'' (comic strip), a long-running comic strip by cartoonist Nicole Hollander Films * ''Sylvia'' (1961 film), an Australian television play * ''Sylvia'' (1965 film), an American drama film * ''Sylvia'' (1985 film), a New Zealand film about New Zealand educator Sylvia Ashton-Warner, * ''Sylvia'' (2003 film), a British biographical drama film a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Science History Institute
The Science History Institute is an institution that preserves and promotes understanding of the history of science. Located in Philadelphia, Pennsylvania, it includes a library, museum, archive, research center and conference center. It was founded in 1982 as a joint venture of the American Chemical Society and the University of Pennsylvania, as the Center for the History of Chemistry (CHOC). The American Institute of Chemical Engineers (AIChE) became a co-founder in 1984. It was renamed the Chemical Heritage Foundation (CHF) in 1992, and moved two years later to the institution's current location, 315 Chestnut Street in Old City, Philadelphia, Old City. On December 1, 2015, CHF merged with the Life Sciences Foundation, creating an organization that covers "the history of the life sciences and biotechnology together with the history of the chemical sciences and engineering." As of February 1, 2018, the organization was renamed the Science History Institute, to reflect its wide ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Society Of Chemical Industry (American Section)
The Society of Chemical Industry (America Section) or SCI America is an independent learned society inspired by the creation of the Society of Chemical Industry (SCI) in London in 1881. Originally known as the New York Section, it was formed in 1894 and officially renamed the America Section in 1919. The main activity of the America Section is the awarding of several prizes in chemistry: the Perkin Medal, the Chemical Industry Medal and the Gordon E. Moore Medal. The America Section also works with the American Chemical Society (ACS) and others to support scholars in chemistry and chemical engineering. History The creation of the Society of Chemical Industry (SCI) in London in 1881 led to the eventual formation of a number of satellite groups. A number of informal meetings were held in 1894, with the goal of organizing a New York section of the Society of Chemical Industry. On May 2, 1894, analytical chemist Arthur McGeorge met with seven other members of London's Society o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Metformin
Metformin, sold under the brand name Glucophage, among others, is the main first-line medication for the treatment of type 2 diabetes, particularly in people who are overweight. It is also used in the treatment of polycystic ovary syndrome. It is not associated with weight gain and is taken by mouth. It is sometimes used as an off-label adjunct to lessen the risk of metabolic syndrome in people who take antipsychotics. Metformin is generally well tolerated. Common adverse effects include diarrhea, nausea, and abdominal pain. It has a small risk of causing low blood sugar. High blood lactic acid level is a concern if the medication is used in overly large doses or prescribed in people with severe kidney problems. It is not recommended in those with significant liver disease. Metformin is a biguanide antihyperglycemic agent. It works by decreasing glucose production in the liver, increasing the insulin sensitivity of body tissues, and increasing GDF15 secretion, which redu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nancy Thornberry
Nancy A. Thornberry is the founding CEO and current Chair, R&D at Kallyope Inc. in New York City. She previously worked with Merck Research Laboratories (MRL), joining the company in 1979 as a biochemist and retiring from the position of Senior Vice President and Franchise Head, Diabetes and Endocrinology in 2013. In 1992, Thornberry identified the first caspase, Caspase-1/Interleukin-1 converting enzyme (ICE). In 1999, Thornberry initiated Merck's research into dipeptidyl peptidase-4, leading to the development of FDA-approved treatments for Type 2 diabetes. She has received a number of awards, including the 2011 PhRMA Discoverer’s Award. Education Thornberry grew up in South Bend, Indiana. As of 1979, she earned a B.Sc. in Natural Science from Muhlenberg College in Allentown, Pennsylvania. Career Thornberry joined Merck Research Laboratories (MRL) in Rahway, New Jersey as a biochemist in 1979. In 1999 she was appointed the Director of Enzymology, and in 2001 the Direct ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
