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Ann Chester Chandley
Ann Chester Chandley DSc, F.I.Biol., FRSE (died 19 February 2020) was an international cytogeneticist with the Medical Research Council unit which became the Human Genetics Unit at the University of Edinburgh. She became a Fellow of the Institute of Biology in recognition of her contribution and a Fellow of the Royal Society of Edinburgh. Career Chandley's work began at Christie Hospital with A.J. Bateman which established principles of sexual selection in gametes. Chandley also worked with Holt Radium Institute, and focussed on mutations and meiosis cell division, using cytogenetic methodology. These studies were on ''Drosophila'' and she completed her PhD in 1968. Chandley then moved on to study genetics in mammals and joined the Human Genetics Unit at Edinburgh. She was a visiting researcher at Cornell University with L. C. Dunn and Dorothea Bennett and Oak Ridge National Laboratory Dan Lindsley and Rhoda Grell. Her research with Herb Stern and Yasuo Hotta which p ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
FRSE
Fellowship of the Royal Society of Edinburgh (FRSE) is an award granted to individuals that the Royal Society of Edinburgh, Scotland's national academy of science and letters, judged to be "eminently distinguished in their subject". This society received a royal charter in 1783, allowing for its expansion. Elections Around 50 new fellows are elected each year in March. there are around 1,650 Fellows, including 71 Honorary Fellows and 76 Corresponding Fellows. Fellows are entitled to use the post-nominal letters FRSE, Honorary Fellows HonFRSE, and Corresponding Fellows CorrFRSE. Disciplines The Fellowship is split into four broad sectors, covering the full range of physical and life sciences, arts, humanities, social sciences, education, professions, industry, business and public life. A: Life Sciences * A1: Biomedical and Cognitive Sciences * A2: Clinical Sciences * A3: Organismal and Environmental Biology * A4: Cell and Molecular Biology B: Physical, Engineering and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dan Lindsley
Dan Lindsley (October 13, 1925 – June 22, 2018) was an American geneticist known for his '' Drosophila'' research. Lindsley was born on October 13, 1925, and raised in California. He attended the University of Texas while serving in the United States Navy during World War II, and pursued a medical degree at the University of Arkansas for Medical Sciences. A. B. Griffen, whom Lindsley first met in Texas, convinced him to transfer to the University of Missouri School of Medicine. There, Lindsley left medicine for biology. After earning his bachelor's and master's degree, Lindsley began doctoral study at the California Institute of Technology in 1949, and completed the program in 1952. Subsequently, he worked at Oak Ridge National Laboratory. Lindsley began teaching at University of California, San Diego in 1967, and retired in 1991. He became a member of the National Academy of Sciences in 1974, and continued academic research decades into retirement. Lindsley died in La Jolla ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Kew Gardens
Kew Gardens is a botanical garden, botanic garden in southwest London that houses the "largest and most diverse botany, botanical and mycology, mycological collections in the world". Founded in 1840, from the exotic garden at Kew Park, its living collections include some of the 27,000 taxa curated by Royal Botanic Gardens, Kew, while the herbarium, one of the largest in the world, has over preserved plant and fungal specimens. The library contains more than 750,000 volumes, and the illustrations collection contains more than 175,000 prints and drawings of plants. It is one of London's top tourist attractions and is a World Heritage Sites, World Heritage Site. Kew Gardens, together with the botanic gardens at Wakehurst Place, Wakehurst in Sussex, are managed by the Royal Botanic Gardens, Kew, an internationally important botany, botanical research and education institution that employs over 1,100 staff and is a non-departmental public body sponsored by the Department for Envir ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Cambridge
, mottoeng = Literal: From here, light and sacred draughts. Non literal: From this place, we gain enlightenment and precious knowledge. , established = , other_name = The Chancellor, Masters and Scholars of the University of Cambridge , type = Public research university , endowment = £7.121 billion (including colleges) , budget = £2.308 billion (excluding colleges) , chancellor = The Lord Sainsbury of Turville , vice_chancellor = Anthony Freeling , students = 24,450 (2020) , undergrad = 12,850 (2020) , postgrad = 11,600 (2020) , city = Cambridge , country = England , campus_type = , sporting_affiliations = The Sporting Blue , colours = Cambridge Blue , website = , logo = University of Cambridge logo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Manchester
, mottoeng = Knowledge, Wisdom, Humanity , established = 2004 – University of Manchester Predecessor institutions: 1956 – UMIST (as university college; university 1994) 1904 – Victoria University of Manchester 1880 – Victoria University 1851 – Owens College 1824 – Manchester Mechanics' Institute , endowment = £242.2 million (2021) , budget = £1.10 billion (2020–21) , chancellor = Nazir Afzal (from August 2022) , head_label = President and vice-chancellor , head = Nancy Rothwell , academic_staff = 5,150 (2020) , total_staff = 12,920 (2021) , students = 40,485 (2021) , undergrad = () , postgrad = () , city = Manchester , country = England, United Kingdom , campus = Urban and suburban , colours = Manchester Purple Manchester Yellow , free_label = Scarf , free = , website = , logo = UniOfManchesterLogo.svg , affiliations = Universities Research Association Sutton 30 Russell Group EUA N8 Group NWUA ACUUniversities UK The Universit ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chromosome
A chromosome is a long DNA molecule with part or all of the genetic material of an organism. In most chromosomes the very long thin DNA fibers are coated with packaging proteins; in eukaryotic cells the most important of these proteins are the histones. These proteins, aided by chaperone proteins, bind to and condense the DNA molecule to maintain its integrity. These chromosomes display a complex three-dimensional structure, which plays a significant role in transcriptional regulation. Chromosomes are normally visible under a light microscope only during the metaphase of cell division (where all chromosomes are aligned in the center of the cell in their condensed form). Before this happens, each chromosome is duplicated ( S phase), and both copies are joined by a centromere, resulting either in an X-shaped structure (pictured above), if the centromere is located equatorially, or a two-arm structure, if the centromere is located distally. The joined copies are now called si ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Down Syndrome Research
Research of Down syndrome-related genes is based on studying the genes located on chromosome 21. In general, this leads to an overexpression of the genes. Understanding the genes involved may help to target medical treatment to individuals with Down syndrome. It is estimated that chromosome 21 contains 200 to 250 genes.See Recent research has identified a region of the chromosome that contains the main genes responsible for the pathogenesis of Down syndrome, located proximal to 21q22.3. The search for major genes involved in Down syndrome characteristics is normally in the region 21q21–21q22.3. Genes Some suspected genes involved in features of Down syndrome are given in the Table 1: General research Research by Arron ''et al.'' shows that some of the phenotypes associated with Down syndrome can be related to the disregulation of transcription factors (596), and in particular, NFAT. NFAT is controlled in part by two proteins, DSCR1 and DYRK1A; these genes are locate ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gene
In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a basic unit of heredity and the molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional RNA. There are two types of molecular genes: protein-coding genes and noncoding genes. During gene expression, the DNA is first copied into RNA. The RNA can be directly functional or be the intermediate template for a protein that performs a function. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. These genes make up different DNA sequences called genotypes. Genotypes along with environmental and developmental factors determine what the phenotypes will be. Most biological traits are under the influence of polygenes (many different genes) as well as gen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
RNA-binding Protein
RNA-binding proteins (often abbreviated as RBPs) are proteins that bind to the double or single stranded RNA in cells and participate in forming ribonucleoprotein complexes. RBPs contain various structural motifs, such as RNA recognition motif (RRM), dsRNA binding domain, zinc finger and others. They are cytoplasmic and nuclear proteins. However, since most mature RNA is exported from the nucleus relatively quickly, most RBPs in the nucleus exist as complexes of protein and pre-mRNA called heterogeneous ribonucleoprotein particles (hnRNPs). RBPs have crucial roles in various cellular processes such as: cellular function, transport and localization. They especially play a major role in post-transcriptional control of RNAs, such as: splicing, polyadenylation, mRNA stabilization, mRNA localization and translation. Eukaryotic cells express diverse RBPs with unique RNA-binding activity and protein–protein interaction. According to the Eukaryotic RBP Database (EuRBPDB), there are 2 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Kun Ma
Kun may refer to: People with the surname * András Kun, Franciscan priest * Béla Kun, Hungarian communist politician * Éva Kun, Hungarian fencer * Kun Can, Chinese painter * Roland Kun, Nauruan politician * Ruben Kun, President of Nauru (1996–1997) * Russ Kun, President of Nauru (2022–) * Russell Kun, Nauruan politician People with the given name or nickname * Cai Xukun Chinese singer, debut from idol producer on the 6th April 2018 * Cao Kun (1862–1938), President of the Republic of China * Chen Kun, Chinese actor and singer * Chen Kun (baseball), Chinese baseball player * Chunyu Kun, Confucian philosopher and official * Feng Kun, Chinese female volleyball player * Hu Kun, Chinese violinist and conductor * Huang Kun, Chinese physicist * Jiang Kun (other), several people * Lee Kwan or Li Kun, Chinese actor * Li Kun, Chinese footballer * Lu Kun (1772–1835), Chinese Qing Dynasty official * Wang Kun (other), several people *Kun Agüero, nickn ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Y Chromosome
The Y chromosome is one of two sex chromosomes (allosomes) in therian mammals, including humans, and many other animals. The other is the X chromosome. Y is normally the sex-determining chromosome in many species, since it is the presence or absence of Y that determines the male or female sex of offspring produced in sexual reproduction. In mammals, the Y chromosome contains the gene SRY, which triggers male development. The DNA in the human Y chromosome is composed of about 59 million base pairs, making it similar in size to chromosome 19. The Y chromosome is passed only from father to son. With a 30% difference between humans and chimpanzees, the Y chromosome is one of the fastest-evolving parts of the human genome. The human Y chromosome carries an estimated 100–200 genes, with between 45 and 73 of these being protein-coding. All single-copy Y-linked genes are hemizygous (present on only one chromosome) except in cases of aneuploidy such as XYY syndrome or XXYY syndrome. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
