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Angle-resolved Low-coherence Interferometry
Angle-resolved low-coherence interferometry (a/LCI) is an emerging biomedical imaging technology which uses the properties of scattered light to measure the average size of cell structures, including cell nuclei. The technology shows promise as a clinical tool for ''in situ'' detection of dysplastic, or precancerous tissue. Introduction A/LCI combines low-coherence interferometry with angle-resolved scattering to solve the inverse problem of determining scatterer geometry based on far field diffraction patterns. Similar to optical coherence domain reflectometry (OCDR) and optical coherence tomography (OCT), a/LCI uses a broadband light source in an interferometry scheme in order to achieve optical sectioning with a depth resolution set by the coherence length of the source. Angle-resolved scattering measurements capture light as a function of the scattering angle, and invert the angles to deduce the average size of the scattering objects via a computational light scatterin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Medical Imaging
Medical imaging is the technique and process of imaging the interior of a body for clinical analysis and medical intervention, as well as visual representation of the function of some organs or tissues (physiology). Medical imaging seeks to reveal internal structures hidden by the skin and bones, as well as to diagnose and treat disease. Medical imaging also establishes a database of normal anatomy and physiology to make it possible to identify abnormalities. Although imaging of removed organ (anatomy), organs and Tissue (biology), tissues can be performed for medical reasons, such procedures are usually considered part of pathology instead of medical imaging. Measurement and recording techniques that are not primarily designed to produce images, such as electroencephalography (EEG), magnetoencephalography (MEG), electrocardiography (ECG), and others, represent other technologies that produce data susceptible to representation as a parameter graph versus time or maps that contain ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Angle
In Euclidean geometry, an angle can refer to a number of concepts relating to the intersection of two straight Line (geometry), lines at a Point (geometry), point. Formally, an angle is a figure lying in a Euclidean plane, plane formed by two Ray (geometry), rays, called the ''Side (plane geometry), sides'' of the angle, sharing a common endpoint, called the ''vertex (geometry), vertex'' of the angle. More generally angles are also formed wherever two lines, rays or line segments come together, such as at the corners of triangles and other polygons. An angle can be considered as the region of the plane bounded by the sides. Angles can also be formed by the intersection of two planes or by two intersecting curves, in which case the rays lying tangent to each curve at the point of intersection define the angle. The term ''angle'' is also used for the size, magnitude (mathematics), magnitude or Physical quantity, quantity of these types of geometric figures and in this context an a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Interference (wave Propagation)
In physics, interference is a phenomenon in which two coherent waves are combined by adding their intensities or displacements with due consideration for their phase difference. The resultant wave may have greater amplitude (constructive interference) or lower amplitude (destructive interference) if the two waves are in phase or out of phase, respectively. Interference effects can be observed with all types of waves, for example, light, radio, acoustic, surface water waves, gravity waves, or matter waves as well as in loudspeakers as electrical waves. Etymology The word ''interference'' is derived from the Latin words ''inter'' which means "between" and ''fere'' which means "hit or strike", and was used in the context of wave superposition by Thomas Young in 1801. Mechanisms The principle of superposition of waves states that when two or more propagating waves of the same type are incident on the same point, the resultant amplitude at that point is equal to the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Michelson–Morley Experiment
The Michelson–Morley experiment was an attempt to measure the motion of the Earth relative to the luminiferous aether, a supposed medium permeating space that was thought to be the carrier of light waves. The experiment was performed between April and July 1887 by American physicists Albert A. Michelson and Edward W. Morley at what is now Case Western Reserve University in Cleveland, Ohio, and published in November of the same year. The experiment compared the speed of light in perpendicular directions in an attempt to detect the relative motion of matter, including their laboratory, through the luminiferous aether, or "aether wind" as it was sometimes called. The result was negative, in that Michelson and Morley found no significant difference between the speed of light in the direction of movement through the presumed aether, and the speed at right angles. This result is generally considered to be the first strong evidence against some aether theories, as well as initiating ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Michelson Interferometer
The Michelson interferometer is a common configuration for optical interferometry and was invented by the American physicist Albert Abraham Michelson in 1887. Using a beam splitter, a light source is split into two arms. Each of those light beams is reflected back toward the beamsplitter which then combines their amplitudes using the superposition principle. The resulting interference pattern that is not directed back toward the source is typically directed to some type of photoelectric detector or camera. For different applications of the interferometer, the two light paths can be with different lengths or incorporate optical elements or even materials under test. The Michelson interferometer is employed in many scientific experiments and became well known for its use by Michelson and Edward Morley in the famous Michelson–Morley experiment (1887) in a configuration which would have detected the Earth's motion through the supposed luminiferous aether that most physicists a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Journal Of The Optical Society Of America A
The ''Journal of the Optical Society of America'' is a peer-reviewed scientific journal of optics, published by Optica. It was established in 1917 and in 1984 was split into two parts, A and B. ''Journal of the Optical Society of America A'' Part A covers various topics in optics, vision, and image science. The editor-in-chief is Olga Korotkova (University of Miami, USA). ''Journal of the Optical Society of America B'' Part B covers various topics in the field of optical physics, such as guided waves, laser spectroscopy, nonlinear optics, quantum optics, laser A laser is a device that emits light through a process of optical amplification based on the stimulated emission of electromagnetic radiation. The word ''laser'' originated as an acronym for light amplification by stimulated emission of radi ...s, organic and polymer materials for optics, and ultrafast phenomena. The editor-in-chief is Kurt Busch ( Humboldt University of Berlin, Germany). References ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Interferometer
Interferometry is a technique which uses the '' interference'' of superimposed waves to extract information. Interferometry typically uses electromagnetic waves and is an important investigative technique in the fields of astronomy, fiber optics, engineering metrology, optical metrology, oceanography, seismology, spectroscopy (and its applications to chemistry), quantum mechanics, nuclear and particle physics, plasma physics, biomolecular interactions, surface profiling, microfluidics, mechanical stress/strain measurement, velocimetry, optometry, and making holograms. Interferometers are devices that extract information from interference. They are widely used in science and industry for the measurement of microscopic displacements, refractive index changes and surface irregularities. In the case with most interferometers, light from a single source is split into two beams that travel in different optical paths, which are then combined again to produce interference; two ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Barrett's Esophagus
Barrett's esophagus is a condition in which there is an abnormal ( metaplastic) change in the mucosal cells that line the lower part of the esophagus. The cells change from stratified squamous epithelium to simple columnar epithelium, interspersed with goblet cells that are normally only found in the small intestine and large intestine. This change is considered to be a premalignant condition because of its potential to transition into esophageal adenocarcinoma, an often-deadly cancer. The main cause of Barrett's esophagus is tissue adaptation to chronic acid exposure caused by reflux from the stomach. Barrett's esophagus is diagnosed by endoscopy to visually observe the lower esophagus, followed by a biopsy of the affected area and microscopic examination of that tissue. The cells of Barrett's esophagus are classified into four categories: nondysplastic, low-grade dysplasia, high-grade dysplasia, and carcinoma. High-grade dysplasia and early stages of adenocarcinoma may be ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Esophagus
The esophagus (American English), oesophagus (British English), or œsophagus (Œ, archaic spelling) (American and British English spelling differences#ae and oe, see spelling difference) all ; : ((o)e)(œ)sophagi or ((o)e)(œ)sophaguses), colloquially known also as the food pipe, food tube, or gullet, is an Organ (anatomy), organ in vertebrates through which food passes, aided by Peristalsis, peristaltic contractions, from the Human pharynx, pharynx to the stomach. The esophagus is a :wiktionary:fibromuscular, fibromuscular tube, about long in adults, that travels behind the trachea and human heart, heart, passes through the Thoracic diaphragm, diaphragm, and empties into the uppermost region of the stomach. During swallowing, the epiglottis tilts backwards to prevent food from going down the larynx and lungs. The word ''esophagus'' is from Ancient Greek οἰσοφάγος (oisophágos), from οἴσω (oísō), future form of φέρω (phérō, "I carry") + ἔφαγον ( ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cervix
The cervix (: cervices) or cervix uteri is a dynamic fibromuscular sexual organ of the female reproductive system that connects the vagina with the uterine cavity. The human female cervix has been documented anatomically since at least the time of Hippocrates, over 2,000 years ago. The cervix is approximately 4 cm long with a diameter of approximately 3 cm and tends to be described as a cylindrical shape, although the front and back walls of the cervix are contiguous. The size of the cervix changes throughout a woman's life cycle. For example, women in the fertile years of their reproductive cycle tend to have larger cervixes than postmenopausal women; likewise, women who have produced offspring have a larger cervix than those who have not. In relation to the vagina, the part of the cervix that opens to the uterus is called the ''internal os'' and the opening of the cervix in the vagina is called the ''external os''. Between them is a conduit commonly called the cervic ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bladder
The bladder () is a hollow organ in humans and other vertebrates that stores urine from the kidneys. In placental mammals, urine enters the bladder via the ureters and exits via the urethra during urination. In humans, the bladder is a distensible organ that sits on the pelvic floor. The typical adult human bladder will hold between 300 and (10 and ) before the urge to empty occurs, but can hold considerably more. The Latin phrase for "urinary bladder" is ''vesica urinaria'', and the term ''vesical'' or prefix ''vesico-'' appear in connection with associated structures such as vesical veins. The modern Latin word for "bladder" – ''cystis'' – appears in associated terms such as cystitis (inflammation of the bladder). Structure In humans, the bladder is a hollow muscular organ situated at the base of the pelvis. In gross anatomy, the bladder can be divided into a broad (base), a body, an apex, and a neck. The apex (also called the vertex) is directed forward toward th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Colon (anatomy)
The large intestine, also known as the large bowel, is the last part of the gastrointestinal tract and of the digestive system in tetrapods. Water is absorbed here and the remaining waste material is stored in the rectum as feces before being removed by defecation. The colon (progressing from the ascending colon to the transverse, the descending and finally the sigmoid colon) is the longest portion of the large intestine, and the terms "large intestine" and "colon" are often used interchangeably, but most sources define the large intestine as the combination of the cecum, colon, rectum, and anal canal. Some other sources exclude the anal canal. In humans, the large intestine begins in the right iliac region of the pelvis, just at or below the waist, where it is joined to the end of the small intestine at the cecum, via the ileocecal valve. It then continues as the colon ascending the abdomen, across the width of the abdominal cavity as the transverse colon, and then desce ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
