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Americans For Medical Advancement
Americans For Medical Advancement (AFMA) is a not-for-profit, science-based, patient advocacy organization dedicated to improving healthcare through biomedical research. It was founded by Ray Greek, MD and his wife, Jean Greek, DVM. The organization opposes the use of animals as causal analogical models, or predictive models, for human response, and argues that using animals as a basis for the human response to drugs is not a safe method of development. For example, efficacy testing, medical research Medical research (or biomedical research), also known as experimental medicine, encompasses a wide array of research, extending from "basic research" (also called ''bench science'' or ''bench research''), – involving fundamental scientif ..., and ADMET (absorption, distribution, metabolism, elimination, and toxicity) are results from animal-based research that were assumed predictive for humans. The organization is relentlessly trying to have a peer reviewed debate with ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Science
Science is a systematic endeavor that builds and organizes knowledge in the form of testable explanations and predictions about the universe. Science may be as old as the human species, and some of the earliest archeological evidence for scientific reasoning is tens of thousands of years old. The earliest written records in the history of science come from Ancient Egypt and Mesopotamia in around 3000 to 1200 BCE. Their contributions to mathematics, astronomy, and medicine entered and shaped Greek natural philosophy of classical antiquity, whereby formal attempts were made to provide explanations of events in the physical world based on natural causes. After the fall of the Western Roman Empire, knowledge of Greek conceptions of the world deteriorated in Western Europe during the early centuries (400 to 1000 CE) of the Middle Ages, but was preserved in the Muslim world during the Islamic Golden Age and later by the efforts of Byzantine Greek scholars who brought Greek ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Patient Advocacy
Patient advocacy is a process in health care concerned with advocacy for patients, survivors, and caregivers. The patient advocate may be an individual or an organization, concerned with healthcare standards or with one specific group of disorders. The terms patient advocate and patient advocacy can refer both to individual advocates providing services that organizations also provide, and to organizations whose functions extend to individual patients. Some patient advocates are independent (with no conflict-of-loyalty issues) and some work for the organizations that are directly responsible for the patient's care. Typical advocacy activities are the following: safeguarding patients from errors, incompetence and misconduct; patient rights, matters of privacy, confidentiality or informed consent, patient representation, awareness building, support and education of patients, survivors and their carers. Patient advocates give a voice to patients, survivors and their carers on hea ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Causal
Causality (also referred to as causation, or cause and effect) is influence by which one event, process, state, or object (''a'' ''cause'') contributes to the production of another event, process, state, or object (an ''effect'') where the cause is partly responsible for the effect, and the effect is partly dependent on the cause. In general, a process has many causes, which are also said to be ''causal factors'' for it, and all lie in its past. An effect can in turn be a cause of, or causal factor for, many other effects, which all lie in its future. Some writers have held that causality is metaphysically prior to notions of time and space. Causality is an abstraction that indicates how the world progresses. As such a basic concept, it is more apt as an explanation of other concepts of progression than as something to be explained by others more basic. The concept is like those of agency and efficacy. For this reason, a leap of intuition may be needed to grasp it. Accordingly ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Efficacy
Efficacy is the ability to perform a task to a satisfactory or expected degree. The word comes from the same roots as ''effectiveness'', and it has often been used synonymously, although in pharmacology a pragmatic clinical trial#Efficacy versus effectiveness, distinction is now often made between efficacy and effectiveness. The word ''efficacy'' is used in pharmacology and medicine to refer both to the maximum response achievable from a pharmaceutical drug in research settings, and to the capacity for sufficient therapeutic effect or beneficial change in clinical settings. Pharmacology In pharmacology, efficacy () is the maximum response achievable from an applied or dosed agent, for instance, a small molecule drug. Intrinsic activity is a relative term for a drug's efficacy relative to a drug with the highest observed efficacy. It is a purely descriptive term that has little or no mechanistic interpretation. In order for a drug to have an effect, it needs to bind to its t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Medical Research
Medical research (or biomedical research), also known as experimental medicine, encompasses a wide array of research, extending from "basic research" (also called ''bench science'' or ''bench research''), – involving fundamental scientific principles that may apply to a ''preclinical'' understanding – to clinical research, which involves studies of people who may be subjects in clinical trials. Within this spectrum is applied research, or translational research, conducted to expand knowledge in the field of medicine. Both clinical and preclinical research phases exist in the pharmaceutical industry's drug development pipelines, where the clinical phase is denoted by the term ''clinical trial''. However, only part of the clinical or preclinical research is oriented towards a specific pharmaceutical purpose. The need for fundamental and mechanism-based understanding, diagnostics, medical devices, and non-pharmaceutical therapies means that pharmaceutical research i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Evolutionary Biology
Evolutionary biology is the subfield of biology that studies the evolutionary processes (natural selection, common descent, speciation) that produced the diversity of life on Earth. It is also defined as the study of the history of life forms on Earth. Evolution is based on the theory that all species are related and they gradually change over time. In a population, the genetic variations affect the physical characteristics i.e. phenotypes of an organism. These changes in the phenotypes will be an advantage to some organisms, which will then be passed onto their offspring. Some examples of evolution in species over many generations are the Peppered Moth and Flightless birds. In the 1930s, the discipline of evolutionary biology emerged through what Julian Huxley called the modern synthesis of understanding, from previously unrelated fields of biological research, such as genetics and ecology, systematics, and paleontology. The importance of studying Evolutionary biology is ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Personalized Medicine
Personalized medicine, also referred to as precision medicine, is a medical model that separates people into different groups—with medical decisions, practices, interventions and/or products being tailored to the individual patient based on their predicted response or risk of disease. The terms personalized medicine, precision medicine, stratified medicine and P4 medicine are used interchangeably to describe this concept though some authors and organisations use these expressions separately to indicate particular nuances. While the tailoring of treatment to patients dates back at least to the time of Hippocrates, the term has risen in usage in recent years given the growth of new diagnostic and informatics approaches that provide understanding of the molecular basis of disease, particularly genomics. This provides a clear evidence base on which to stratify (group) related patients. Among the 14 Grand Challenges for Engineering, an initiative sponsored by National Academy of En ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
United States Environmental Protection Agency
The Environmental Protection Agency (EPA) is an independent executive agency of the United States federal government tasked with environmental protection matters. President Richard Nixon proposed the establishment of EPA on July 9, 1970; it began operation on December 2, 1970, after Nixon signed an executive order. The order establishing the EPA was ratified by committee hearings in the House and Senate. The agency is led by its administrator, who is appointed by the president and approved by the Senate. The current administrator is Michael S. Regan. The EPA is not a Cabinet department, but the administrator is normally given cabinet rank. The EPA has its headquarters in Washington, D.C., regional offices for each of the agency's ten regions and 27 laboratories. The agency conducts environmental assessment, research, and education. It has the responsibility of maintaining and enforcing national standards under a variety of environmental laws, in consultation with state, tr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
National Institutes Of Health
The National Institutes of Health, commonly referred to as NIH (with each letter pronounced individually), is the primary agency of the United States government responsible for biomedical and public health research. It was founded in the late 1880s and is now part of the United States Department of Health and Human Services. The majority of NIH facilities are located in Bethesda, Maryland, and other nearby suburbs of the Washington metropolitan area, with other primary facilities in the Research Triangle Park in North Carolina and smaller satellite facilities located around the United States. The NIH conducts its own scientific research through the NIH Intramural Research Program (IRP) and provides major biomedical research funding to non-NIH research facilities through its Extramural Research Program. , the IRP had 1,200 principal investigators and more than 4,000 postdoctoral fellows in basic, translational, and clinical research, being the largest biomedical research instit ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Skeptic (US Magazine)
''Skeptic'', colloquially known as ''Skeptic magazine'', is a quarterly science education and science advocacy magazine published internationally by The Skeptics Society, a nonprofit organization devoted to promoting scientific skepticism and resisting the spread of pseudoscience, superstition, and irrationality, irrational beliefs. First published in 1992, the magazine had a circulation of over 50,000 subscribers in 2015. History, format and structure The magazine was co-founded in late 1991 by Michael Shermer and Pat Linse as they formed the Skeptics Society. The magazine was first published in the spring of 1992. It is published through Millennium Press. As of July 2021, Shermer remained the publisher and editor-in-chief of the magazine. The magazine's co-publisher and art director was Pat Linse, until her death in July 2021. Other noteworthy members of its editorial board include, or have included, Oxford University evolutionary biology, evolutionary biologist Richard Dawki ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
List Of Animal Rights Groups
This list of animal rights groups consists of groups in the animal rights movement. Such animal rights groups work towards their ideals, which include the viewpoint that animals should have equivalent rights to humans, such as not being "used" in research, food, clothing and entertainment industries, and seek to end the status of animals as property. (Cf. Animal welfare.) This list contains only groups, organizations and leaderless resistance networks that have articles within Wikipedia. Organizations General animal rights *American Society for the Prevention of Cruelty to Animals (ASPCA) *Animal Aid (UK) *Animal Defenders International *Animal Defense League *Animal Ethics *Animal Legal Defense Fund *Animal Liberation Leagues *Animal Liberation Press Office * Animal Outlook (formerly Compassion Over Killing) *Animal Protection and Rescue League *Animal Welfare Network Nepal * AnimaNaturalis (Spain and Latin America) *Animals Now *Anonymous for the Voiceless *Best Friends Anim ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Healthcare Reform Advocacy Groups In The United States
Healthcare reform advocacy groups in the United States are non-profit organizations in the US who have as one of their primary goals healthcare reform in the United States. These notable organizations address issues such as universal healthcare, national health insurance, and single-payer healthcare. Advocacy groups * American Medical Student Association * American Nurses Association * Business Leaders for Health Care Transformation https://www.blhct.org * California Nurses Association/National Nurses Organizing Committee * Campaign for Better Health CareCenter for Health ProgressColorado Consumer Health InitiativeConsumers for Affordable Health CareCommunity Catalyst*Doctors For America * Families USA Florida Voices for HealthGeorgians for a Healthy FutureHealth Access CaliforniaHealth Action New MexicoHealth Care for All(Massachusetts) * Health Care for All Minnesota https://hca-mn.org * Health Care for America NOW! * Healthcare-NOW! Kentucky Voices for HealthMaryland Health ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
