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Aknadinine
Aknadinine (also known as 4-demethylhasubanonine) is an opioid alkaloid isolated from members of the genus Stephania ('' Stephania cepharantha'' and '' Stephania hernandifolia''.). Structurally it is a member of the hasubanan family of alkaloids and features an isoquinoline substructure. See also * Hasubanonine Hasubanonine is a member of the hasubanan family of alkaloids. The alkaloid with an isoquinoline substructure has the molecular formula of C21H27NO5. The enantiomer of the natural product is being studied as a potential painkiller. Hasubanonine i ... References Opioids Pyrrolidine alkaloids {{alkaloid-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Opioid
Opioids are substances that act on opioid receptors to produce morphine-like effects. Medically they are primarily used for pain relief, including anesthesia. Other medical uses include suppression of diarrhea, replacement therapy for opioid use disorder, reversing opioid overdose, and suppressing cough. Extremely potent opioids such as carfentanil are approved only for veterinary use. Opioids are also frequently used non-medically for their euphoric effects or to prevent withdrawal. Opioids can cause death and have been used for executions in the United States. Side effects of opioids may include itchiness, sedation, nausea, respiratory depression, constipation, and euphoria. Long-term use can cause tolerance, meaning that increased doses are required to achieve the same effect, and physical dependence, meaning that abruptly discontinuing the drug leads to unpleasant withdrawal symptoms. The euphoria attracts recreational use, and frequent, escalating recreational use of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alkaloid
Alkaloids are a class of basic, naturally occurring organic compounds that contain at least one nitrogen atom. This group also includes some related compounds with neutral and even weakly acidic properties. Some synthetic compounds of similar structure may also be termed alkaloids. In addition to carbon, hydrogen and nitrogen, alkaloids may also contain oxygen, sulfur and, more rarely, other elements such as chlorine, bromine, and phosphorus.Chemical Encyclopedia: alkaloids xumuk.ru Alkaloids are produced by a large variety of organisms including , , Medicinal plant, plants, an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Stephania
''Stephania'' is a genus of flowering plants in the family Menispermaceae, native to eastern and southern Asia and Australia. They are herbaceous perennial vines, growing to around four metres tall, with a large tuber. The leaves are arranged spirally on the stem and are peltate, with the leaf petiole attached near the centre of the leaf. The name ''Stephania'' comes from the Greek, "a crown". This refers to the anthers being arranged in a crown-like manner. One species, '' S. tetrandra'', is among the 50 fundamental herbs used in traditional Chinese medicine, where it is called ''han fang ji'' (漢防己, "Chinese ''fang ji''"). Other plants named ''fang ji'' are sometimes substituted for it. Other varieties substituted include '' Cocculus thunbergii'', '' C. trulobus'', ''Aristolochia fangchi'', ''Stephania tetrandria'', and '' Sinomenium acutum''. Notable among these is ''guang fang ji'' (廣防己, "(GuangDong, GuangXi) fang ji", ''Aristolochia fangchi''. Because of its toxi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Stephania Cepharantha
''Stephania'' is a genus of flowering plants in the family Menispermaceae, native to eastern and southern Asia and Australia. They are herbaceous perennial vines, growing to around four metres tall, with a large tuber. The leaves are arranged spirally on the stem and are peltate, with the leaf petiole attached near the centre of the leaf. The name ''Stephania'' comes from the Greek, "a crown". This refers to the anthers being arranged in a crown-like manner. One species, '' S. tetrandra'', is among the 50 fundamental herbs used in traditional Chinese medicine, where it is called ''han fang ji'' (漢防己, "Chinese ''fang ji''"). Other plants named ''fang ji'' are sometimes substituted for it. Other varieties substituted include ''Cocculus thunbergii'', '' C. trulobus'', ''Aristolochia fangchi'', '' Stephania tetrandria'', and ''Sinomenium acutum''. Notable among these is ''guang fang ji'' (廣防己, "(GuangDong, GuangXi) fang ji", ''Aristolochia fangchi''. Because of it ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Zhong Yao Cai
{{disambig ...
Zhong can refer to * Zhong (surname), pinyin romanization of Chinese surnames including 钟, 种, 仲, etc. * Zhong County, a county of Chongqing, China * Zhongjian River, a river in Hubei, China * Bianzhong, a Chinese musical instrument similar to a bell * Cha zhong, a 3-piece tea brewing vessel, also known as a ''gaiwan''. * The Mean 中, concept of Chinese philosophy (see Doctrine of the Mean) * Loyalty :zh:忠, one of the precepts in Confucianism. See also * Chong (other) Chong may refer to: * Chong (surname), the romanization of several Chinese and Korean surnames * Chong or Pear people of Thailand and Cambodia ** Chong language * Chong or Limbu people of eastern Nepal, Bhutan, and northeastern India * ancient Chi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Stephania Hernandifolia
''Stephania'' is a genus of flowering plants in the family Menispermaceae, native to eastern and southern Asia and Australia. They are herbaceous perennial vines, growing to around four metres tall, with a large tuber. The leaves are arranged spirally on the stem and are peltate, with the leaf petiole attached near the centre of the leaf. The name ''Stephania'' comes from the Greek, "a crown". This refers to the anthers being arranged in a crown-like manner. One species, '' S. tetrandra'', is among the 50 fundamental herbs used in traditional Chinese medicine, where it is called ''han fang ji'' (漢防己, "Chinese ''fang ji''"). Other plants named ''fang ji'' are sometimes substituted for it. Other varieties substituted include ''Cocculus thunbergii'', '' C. trulobus'', ''Aristolochia fangchi'', '' Stephania tetrandria'', and ''Sinomenium acutum''. Notable among these is ''guang fang ji'' (廣防己, "(GuangDong, GuangXi) fang ji", ''Aristolochia fangchi''. Because of it ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Journal Of Organic Chemistry
''The Journal of Organic Chemistry'', colloquially known as ''JOC'', is a peer-reviewed scientific journal for original contributions of fundamental research in all branches of theory and practice in organic and bioorganic chemistry. It is published by the publishing arm of the American Chemical Society, with 24 issues per year. According to the ''Journal Citation Reports'', the journal had a 2017 impact factor of 4.805 and it is the journal that received the most cites (100,091 in 2017) in the field of organic chemistry. According to Web of Knowledge (and as December 2012), eleven papers from the journal have received more than 1,000 citations, with the most cited paper having received 7,967 citations. The current editor-in-chief is Scott J. Miller from Yale University. Indexing ''J. Org. Chem.'' is currently indexed in: See also *Organic Letters *Organometallics ''Organometallics'' is a biweekly journal published by the American Chemical Society. Its area of focus is ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hasubanan
Hasubanan is an alkaloid with the chemical formula of C16H21N. It forms the central core of a class of alkaloids known collectively as hasubanans. The compound is derived from reticuline, as is morphinan Morphinan is the prototype chemical structure of a large chemical class of psychoactive drugs, consisting of opiate analgesics, cough suppressants, and dissociative hallucinogens, among others. Structure Morphinan has a phenanthrene core struct ..., but is comparatively more oxidized and rearranged. It is similar to acutumine. Various alkaloids of this family have been synthesized in the laboratories. See also * Hasubanonine References External links Synthesis at chem.wisc.edu Pyrrolidine alkaloids {{alkaloid-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Isoquinoline
Isoquinoline is a heterocyclic aromatic organic compound. It is a structural isomer of quinoline. Isoquinoline and quinoline are benzopyridines, which are composed of a benzene ring fused to a pyridine ring. In a broader sense, the term isoquinoline is used to make reference to isoquinoline derivatives. 1-Benzylisoquinoline is the structural backbone in naturally occurring alkaloids including papaverine. The isoquinoline ring in these natural compound derives from the aromatic amino acid tyrosine. Properties Isoquinoline is a colorless hygroscopic liquid at temperatures above its melting point with a penetrating, unpleasant odor. Impure samples can appear brownish, as is typical for nitrogen heterocycles. It crystallizes in platelets that have a low solubility in water but dissolve well in ethanol, acetone, diethyl ether, carbon disulfide, and other common organic solvents. It is also soluble in dilute acids as the protonated derivative. Being an analog of pyridine, isoquinolin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hasubanonine
Hasubanonine is a member of the hasubanan family of alkaloids. The alkaloid with an isoquinoline substructure has the molecular formula of C21H27NO5. The enantiomer of the natural product is being studied as a potential painkiller. Hasubanonine is structurally related to the morphinan class of opioid analgesics An analgesic drug, also called simply an analgesic (American English), analgaesic (British English), pain reliever, or painkiller, is any member of the group of drugs used to achieve relief from pain (that is, analgesia or pain management). It i .... The enantioselective total synthesis of (–)-hasubanonine and related natural products, (−)-runanine, (−)-delavayine, and (+)-periglaucine B were first achieved by Prof. Seth Herzon and co-workers at Yale University in 2011. References Alkaloids Phenol ethers Enones {{heterocyclic-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Opioids
Opioids are substances that act on opioid receptors to produce morphine-like effects. Medically they are primarily used for pain relief, including anesthesia. Other medical uses include suppression of diarrhea, replacement therapy for opioid use disorder, reversing opioid overdose, and suppressing cough. Extremely potent opioids such as carfentanil are approved only for veterinary use. Opioids are also frequently used non-medically for their euphoric effects or to prevent withdrawal. Opioids can cause death and have been used for executions in the United States. Side effects of opioids may include itchiness, sedation, nausea, respiratory depression, constipation, and euphoria. Long-term use can cause tolerance, meaning that increased doses are required to achieve the same effect, and physical dependence, meaning that abruptly discontinuing the drug leads to unpleasant withdrawal symptoms. The euphoria attracts recreational use, and frequent, escalating recreational use of o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
