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Agitated Nutsche Filter
Agitated Nutsche filter (ANF) is a filtration technique used in applications such as dye, paint, and pharmaceutical production and waste water treatment. Safety requirements and environmental concerns due to solvent evaporation led to the development of this type of filter wherein filtration under vacuum or pressure can be carried out in closed vessels and solids can be discharged straightaway into a dryer. Filter features A typical unit consists of a dished vessel with a perforated plate. The entire vessel can be kept at the desired temperature by using a limpet jacket, jacketed bottom dish and stirrer (blade and shaft) through which heat transfer media can flow. The vessel can be made completely leak-proof for vacuum or pressure service. Nutsche filter disc The filter disc is the bottom porous plate of the nutsche filter. The filter disc retains the solids and lets the liquid/ gas passing through. It is the main filtration component of the nutsche filter. Types of the fi ...
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Kilopascal
The pascal (symbol: Pa) is the unit of pressure in the International System of Units (SI), and is also used to quantify internal pressure, stress, Young's modulus, and ultimate tensile strength. The unit, named after Blaise Pascal, is defined as one newton per square metre and is equivalent to 10 barye (Ba) in the CGS system. The unit of measurement called standard atmosphere (atm) is defined as 101,325 Pa. Common multiple units of the pascal are the hectopascal (1 hPa = 100 Pa), which is equal to one millibar, and the kilopascal (1 kPa = 1000 Pa), which is equal to one centibar. Meteorological observations typically report atmospheric pressure in hectopascals per the recommendation of the World Meteorological Organization, thus a standard atmosphere (atm) or typical sea-level air pressure is about 1013 hPa. Reports in the United States typically use inches of mercury or millibars (hectopascals). In Canada these reports are given in kilopascals ...
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Active Pharmaceutical Ingredient
An active ingredient is any ingredient that provides biological activity, biologically active or other direct effect in the diagnosis, cure, mitigation, treatment, or prevention of disease or to affect the structure or any function of the body of humans or animals. The similar terms active pharmaceutical ingredient (also abbreviated as API) and bulk active are also used in medicine, and the term active substance may be used for Natural product, natural products. Some medication products may contain more than one active ingredient. The traditional word for the active pharmaceutical agent is pharmacon or pharmakon (from el, φάρμακον, adapted from ''pharmacos'') which originally denoted a Potion, magical substance or drug. The terms active constituent or active principle are often chosen when referring to the active chemical substance, substance of interest in a plant (such as salicylic acid in willow bark or arecoline in areca nuts), because the word "ingredient" in many m ...
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Filter Dryer
A filter drier is a piece of process equipment used during the filtration and drying phase of a pharmaceutical, bio pharmaceutical or chemical process for an active pharmaceutical ingredient (API) or other compounds production. Filter dryers are designed for washing and isolating solids with or without integrated containment systems.Maurice Pitcher, PSL, http://www.powdersystems.com/Filter Dryers-FilterDriers.html, 2011. Several actions have to be undertaken as part of the filtration and drying process including: *slurry charging *pressurized and / or vacuum filtration *controlled heating and cooling *cake smoothing and drying *contained discharging and sampling *vapor trap column, to trap solids particles ( fines ) carrying over with vapors *Clean-In-Place (CIP)Christian Parker (May 2012), Pharmaceutical Manufacturing and Packing Sourcer Magazine (PMPS). An agitated nutsche filter dryer (ANFD) is one class of such filter dryers that has been specifically designed so all these o ...
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Borosilicate Glass
Borosilicate glass is a type of glass with silica and boron trioxide as the main glass-forming constituents. Borosilicate glasses are known for having very low coefficients of thermal expansion (≈3 × 10−6 K−1 at 20 °C), making them more resistant to thermal shock than any other common glass. Such glass is subjected to less thermal stress and can withstand temperature differentials without fracturing of about . It is commonly used for the construction of reagent bottles and flasks as well as lighting, electronics, and cookware. Borosilicate glass is sold under various trade names, including Borosil, Duran, Pyrex, Glassco, Supertek, Suprax, Simax, Bellco, Marinex (Brazil), BSA 60, BSC 51 (by NIPRO), Heatex, Endural, Schott, Refmex, Kimax, Gemstone Well, and MG (India). Single ended self-starting lamps are insulated with a mica disc and contained in a borosilicate glass gas discharge tube (arc tube) and a metal cap. They include the sodium-vapor lamp tha ...
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Fibre-reinforced Plastic
Fibre-reinforced plastic (FRP; also called fibre-reinforced polymer, or in American English ''fiber'') is a composite material made of a polymer matrix reinforced with fibres. The fibres are usually glass (in fibreglass), carbon (in carbon-fibre-reinforced polymer), aramid, or basalt. Rarely, other fibres such as paper, wood, or asbestos have been used. The polymer is usually an epoxy, vinyl ester, or polyester thermosetting plastic, though phenol formaldehyde resins are still in use. FRPs are commonly used in the aerospace, automotive, marine, and construction industries. They are commonly found in ballistic armour and cylinders for self-contained breathing apparatuses. Process definition A polymer is generally manufactured by step-growth polymerization or addition polymerization. When combined with various agents to enhance or in any way alter the material properties of polymers, the result is referred to as a plastic. Composite plastics refers to those types of plastic ...
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Polypropylene
Polypropylene (PP), also known as polypropene, is a thermoplastic polymer used in a wide variety of applications. It is produced via chain-growth polymerization from the monomer propylene. Polypropylene belongs to the group of polyolefins and is partially crystalline and non-polar. Its properties are similar to polyethylene, but it is slightly harder and more heat-resistant. It is a white, mechanically rugged material and has a high chemical resistance. Bio-PP is the bio-based counterpart of polypropylene (PP). Polypropylene is the second-most widely produced commodity plastic (after polyethylene). In 2019, the global market for polypropylene was worth $126.03 billion. Revenues are expected to exceed US$145 billion by 2019. The sales of this material are forecast to grow at a rate of 5.8% per year until 2021. History Phillips Petroleum chemists J. Paul Hogan and Robert Banks first demonstrated the polymerization of propylene in 1951. The stereoselective polymerization t ...
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Rubber
Rubber, also called India rubber, latex, Amazonian rubber, ''caucho'', or ''caoutchouc'', as initially produced, consists of polymers of the organic compound isoprene, with minor impurities of other organic compounds. Thailand, Malaysia, and Indonesia are three of the leading rubber producers. Types of polyisoprene that are used as natural rubbers are classified as elastomers. Currently, rubber is harvested mainly in the form of the latex from the rubber tree (''Hevea brasiliensis'') or others. The latex is a sticky, milky and white colloid drawn off by making incisions in the bark and collecting the fluid in vessels in a process called "tapping". The latex then is refined into the rubber that is ready for commercial processing. In major areas, latex is allowed to coagulate in the collection cup. The coagulated lumps are collected and processed into dry forms for sale. Natural rubber is used extensively in many applications and products, either alone or in combination wit ...
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Mild Steel
Carbon steel is a steel with carbon content from about 0.05 up to 2.1 percent by weight. The definition of carbon steel from the American Iron and Steel Institute (AISI) states: * no minimum content is specified or required for chromium, cobalt, molybdenum, nickel, niobium, titanium, tungsten, vanadium, zirconium, or any other element to be added to obtain a desired alloying effect; * the specified minimum for copper does not exceed 0.40%; * or the maximum content specified for any of the following elements does not exceed the percentages noted: manganese 1.65%; silicon 0.60%; copper 0.60%. The term ''carbon steel'' may also be used in reference to steel which is not stainless steel; in this use carbon steel may include alloy steels. High carbon steel has many different uses such as milling machines, cutting tools (such as chisels) and high strength wires. These applications require a much finer microstructure, which improves the toughness. Carbon steel is a popular metal choic ...
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Stainless Steel
Stainless steel is an alloy of iron that is resistant to rusting and corrosion. It contains at least 11% chromium and may contain elements such as carbon, other nonmetals and metals to obtain other desired properties. Stainless steel's corrosion resistance, resistance to corrosion results from the chromium, which forms a Passivation (chemistry), passive film that can protect the material and self-healing material, self-heal in the presence of oxygen. The alloy's properties, such as luster and resistance to corrosion, are useful in many applications. Stainless steel can be rolled into Sheet metal, sheets, plates, bars, wire, and tubing. These can be used in cookware, cutlery, surgical instruments, major appliances, vehicles, construction material in large buildings, industrial equipment (e.g., in paper mills, chemical plants, water treatment), and storage tanks and tankers for chemicals and food products. The biological cleanability of stainless steel is superior to both alumi ...
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Hastelloy
Haynes International, Inc., headquartered in Kokomo, Indiana, is one of the largest producers of corrosion-resistant and high-temperature alloys. In addition to Kokomo, Haynes has manufacturing facilities in Arcadia, Louisiana, and Mountain Home, North Carolina. The Kokomo facility specializes in flat products, the Arcadia facility in tubular products, and the Mountain Home facility in wire products. In fiscal year 2018, the company's revenues were derived from the aerospace (52.1%), chemical processing (18.2%), industrial gas turbine (12.0%) and other (12.3%) industries. The company's alloys are primarily marketed under the Hastelloy and the Haynes brands. They are based on nickel, but also include cobalt, chromium, molybdenum, tungsten, iron, silicon, manganese, carbon, aluminum, and/or titanium. History The company was founded by Elwood Haynes in 1912 in Kokomo, Indiana, as Haynes Stellite Works. Haynes had recently received a patent for a metal he created, which he named Stel ...
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Kilogram-force Per Square Centimetre
A kilogram-force per centimetre square (kgf/cm2), often just kilogram per square centimetre (kg/cm2), or kilopond per centimetre square is a deprecated unit of pressure using metric units. It is not a part of the International System of Units (SI), the modern metric system. 1 kgf/cm2 equals 98.0665 kPa (kilopascals). It is also known as a technical atmosphere (symbol: at). The kilogram-force per square centimetre remains active as a measurement of force primarily due to older pressure measurement devices still in use. This use of the unit of pressure provides an intuitive understanding for how a body's ''mass'' can apply ''force'' to a scale's ''surface area'' i.e.kilogram-force per square (centi-)metre. In SI units, the unit is converted to the SI derived unit pascal (Pa), which is defined as one newton per square metre (N/m2). A newton is equal to 1 kg⋅m/s2, and a kilogram-force is 9.80665 N,
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