Adenylosuccinate
Adenylosuccinate is an intermediate in the interconversion of purine nucleotides inosine monophosphate (IMP) and adenosine monophosphate (AMP). The enzyme adenylosuccinate synthase carries out the reaction by the addition of aspartate to IMP and requires the input of energy from a phosphoanhydride bond in the form of guanosine triphosphate (GTP).Figures 20.4 and 20.7 in ''Textbook of Biochemistry'', with clinical correlations, Sixth Edition, Thomas M. Devlin, Ed., Wiley-Liss, Inc., New York, NY, 2006 GTP is used instead of adenosine triphosphate (ATP), so the reaction is not dependent on its products. See also * Adenylosuccinate lyase deficiency * Purine nucleotide cycle Purine is a heterocyclic aromatic organic compound that consists of two rings (pyrimidine and imidazole) fused together. It is water-soluble. Purine also gives its name to the wider class of molecules, purines, which include substituted purines a ... References Nucleotides {{biochem-stub ...
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