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Adam Nash (savior Sibling)
Adam Nash (born August 29, 2000) is an American who was conceived using preimplantation genetic diagnosis (PGD). Early life His parents conceived him through in-vitro fertilization and preimplantation genetic diagnosis (PGD) so he could donate cord blood to Molly his sister, who was born with Fanconi anemia, and be free of the disease himself. Nash was born on August 29, 2000, by Caesarean section. In October 2000, the blood from his umbilical cord was transplanted to his sister. Nash's conception and birth received both praise and criticism due to the ethical issues surrounding PGD and was also the inspiration of the novel '' My Sister's Keeper'' by Jodi Picoult. Nash has been called "the world's first savior sibling" and "the first designer baby A designer baby is a baby whose genetic makeup has been selected or altered, often to not include a particular gene or to remove genes associated with disease. This process usually involves analysing a wide range of human embryos ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Preimplantation Genetic Diagnosis
Preimplantation genetic diagnosis (PGD or PIGD) is the genetic profiling of embryos prior to implantation (as a form of embryo profiling), and sometimes even of oocytes prior to fertilization. PGD is considered in a similar fashion to prenatal diagnosis. When used to screen for a specific genetic disease, its main advantage is that it avoids selective abortion, as the method makes it highly likely that the baby will be free of the disease under consideration. PGD thus is an adjunct to assisted reproductive technology, and requires in vitro fertilization (IVF) to obtain oocytes or embryos for evaluation. Embryos are generally obtained through blastomere or blastocyst biopsy. The latter technique has proved to be less deleterious for the embryo, therefore it is advisable to perform the biopsy around day 5 or 6 of development. The world's first PGD was performed by Handyside, Kontogianni and Winston at the Hammersmith Hospital in London. Female embryos were selectively transferre ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
In-vitro Fertilization
In vitro fertilisation (IVF) is a process of fertilisation where an egg is combined with sperm in vitro ("in glass"). The process involves monitoring and stimulating an individual's ovulatory process, removing an ovum or ova (egg or eggs) from their ovaries and letting sperm fertilise them in a culture medium in a laboratory. After the fertilised egg (zygote) undergoes embryo culture for 2–6 days, it is transferred by catheter into the uterus, with the intention of establishing a successful pregnancy. IVF is a type of assisted reproductive technology used for infertility treatment, gestational surrogacy, and, in combination with pre-implantation genetic testing, avoiding transmission of genetic conditions. A fertilised egg from a donor may implant into a surrogate's uterus, and the resulting child is genetically unrelated to the surrogate. Some countries have banned or otherwise regulate the availability of IVF treatment, giving rise to fertility tourism. Restrictio ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Preimplantation Genetic Diagnosis
Preimplantation genetic diagnosis (PGD or PIGD) is the genetic profiling of embryos prior to implantation (as a form of embryo profiling), and sometimes even of oocytes prior to fertilization. PGD is considered in a similar fashion to prenatal diagnosis. When used to screen for a specific genetic disease, its main advantage is that it avoids selective abortion, as the method makes it highly likely that the baby will be free of the disease under consideration. PGD thus is an adjunct to assisted reproductive technology, and requires in vitro fertilization (IVF) to obtain oocytes or embryos for evaluation. Embryos are generally obtained through blastomere or blastocyst biopsy. The latter technique has proved to be less deleterious for the embryo, therefore it is advisable to perform the biopsy around day 5 or 6 of development. The world's first PGD was performed by Handyside, Kontogianni and Winston at the Hammersmith Hospital in London. Female embryos were selectively transferre ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fanconi Anemia
Fanconi anaemia (FA) is a rare genetic disease resulting in impaired response to DNA damage. Although it is a very rare disorder, study of this and other bone marrow failure syndromes has improved scientific understanding of the mechanisms of normal bone marrow function and development of cancer. Among those affected, the majority develop cancer, most often acute myelogenous leukemia (AML), and 90% develop aplastic anemia (the inability to produce blood cells) by age 40. About 60–75% have congenital defects, commonly short stature, abnormalities of the skin, arms, head, eyes, kidneys, and ears, and developmental disabilities. Around 75% have some form of endocrine problem, with varying degrees of severity. FA is the result of a genetic defect in a cluster of proteins responsible for DNA repair via homologous recombination. Treatment with androgens and hematopoietic (blood cell) growth factors can help bone marrow failure temporarily, but the long-term treatment is bone mar ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Caesarean Section
Caesarean section, also known as C-section or caesarean delivery, is the surgical procedure by which one or more babies are delivered through an incision in the mother's abdomen, often performed because vaginal delivery would put the baby or mother at risk. Reasons for the operation include obstructed labor, twin pregnancy, high blood pressure in the mother, breech birth, and problems with the placenta or umbilical cord. A caesarean delivery may be performed based upon the shape of the mother's pelvis or history of a previous C-section. A trial of vaginal birth after C-section may be possible. The World Health Organization recommends that caesarean section be performed only when medically necessary. Most C-sections are performed without a medical reason, upon request by someone, usually the mother. A C-section typically takes 45 minutes to an hour. It may be done with a spinal block, where the woman is awake, or under general anesthesia. A urinary catheter is used to d ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
My Sister's Keeper (novel)
''My Sister's Keeper'' (2004) is the eleventh novel by the American author Jodi Picoult. It tells the story of thirteen-year-old Anna Fitzgerald, who sues her parents for medical emancipation when she is told to donate a kidney to her elder sister Kate, who is gradually dying from acute leukemia. Summary The story takes place in the fictional town of Upper Darby, Rhode Island in 2004. Anna Fitzgerald's older sister, Kate, suffers from acute promyelocytic leukemia, a blood and bone marrow cancer. Anna was born as a savior sister specifically so she could save Kate's life through the donation of her umbilical cord blood. At first it is successful, but the cancer continues to relapse throughout Kate's life. Anna is usually willing to donate whatever Kate needs, but when she turns 13, she is told that she will have to donate one of her kidneys due to Kate's kidney failure. The surgery required for both Kate and Anna would be major; it is not guaranteed to work, as the stress of the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Jodi Picoult
Jodi Lynn Picoult () is an American writer. Picoult has published 28 novels, accompanying short stories, and has also written several issues of Wonder Woman. Approximately 40 million copies of her books are in print worldwide, translated into 34 languages. She was awarded the New England Bookseller Award for fiction in 2003. Picoult writes popular fiction which can be characterised as family saga. She frequently centres storylines around a moral dilemma or a procedural drama which pits family members against one another. Although she is often characterised as an author of chick-lit, over her career, Picoult has covered a wide range of controversial or moral issues, including abortion, assisted suicide, race relations, eugenics, LGBT rights, fertility issues, religion, the death penalty, and school shootings. She has been described as, "a paradox, a hugely popular, at times controversial writer, ignored by academia, who questions notions of what constitutes literature simply b ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Designer Baby
A designer baby is a baby whose genetic makeup has been selected or altered, often to not include a particular gene or to remove genes associated with disease. This process usually involves analysing a wide range of human embryos to identify genes associated with particular diseases and characteristics, and selecting embryos that have the desired genetic makeup; a process known as preimplantation genetic diagnosis. Screening for single genes is commonly practiced, and polygenic screening is offered by a few companies. Other potential methods by which a baby's genetic information can be altered involve directly editing the genome before birth, which is not routinely performed and only one instance of this is known to have occurred as of 2019, where Chinese twins Lulu and Nana were edited as embryos, causing widespread criticism. Genetically altered embryos can be achieved by introducing the desired genetic material into the embryo itself, or into the sperm and/or egg cells of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Living People
Related categories * :Year of birth missing (living people) / :Year of birth unknown * :Date of birth missing (living people) / :Date of birth unknown * :Place of birth missing (living people) / :Place of birth unknown * :Year of death missing / :Year of death unknown * :Date of death missing / :Date of death unknown * :Place of death missing / :Place of death unknown * :Missing middle or first names See also * :Dead people * :Template:L, which generates this category or death years, and birth year and sort keys. : {{DEFAULTSORT:Living people 21st-century people People by status ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
