Actinomyces Massiliensis
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Actinomyces Massiliensis
''Actinomyces massiliensis'' is an anaerobic, mesophilic, Gram-positive bacterium originally isolated from a human blood sample and belonging to the genus '' Actinomyces''. Etymology The genus name, '' Actinomyces'', borrows from the Greek words "aktinos" and "mykēs" which refer to ray and fungus, respectively. When combined, ''Actinomyces'' translates to "ray fungus", reflecting the radial arrangement of filaments in addition to the presence of asexual spores, both of which are characteristic of filamentous fungus. This corresponds to the misconception that upon discovery they were fungi due to their long cells branching into structures resembling filaments and hyphae. Marseille, the town in France where the original type strain was found, is inspiration for the species name, ''massiliensis'', with old Greek and Roman language origins. Discovery and isolation In December 2003, a middle-aged man was hospitalized due to the coughing up of blood accompanied by flu-like ...
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Anaerobic Organism
An anaerobic organism or anaerobe is any organism that does not require molecular oxygen for growth. It may react negatively or even die if free oxygen is present. In contrast, an aerobic organism (aerobe) is an organism that requires an oxygenated environment. Anaerobes may be unicellular (e.g. protozoans, bacteria) or multicellular. Most fungi are obligate aerobes, requiring oxygen to survive. However, some species, such as the Chytridiomycota that reside in the rumen of cattle, are obligate anaerobes; for these species, anaerobic respiration is used because oxygen will disrupt their metabolism or kill them. Deep waters of the ocean are a common anoxic environment. First observation In his letter of 14 June 1680 to The Royal Society, Antonie van Leeuwenhoek described an experiment he carried out by filling two identical glass tubes about halfway with crushed pepper powder, to which some clean rain water was added. Van Leeuwenhoek sealed one of the glass tubes using a flame an ...
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BLAST (biotechnology)
In bioinformatics, BLAST (basic local alignment search tool) is an algorithm and program for comparing primary biological sequence information, such as the amino-acid sequences of proteins or the nucleotides of DNA and/or RNA sequences. A BLAST search enables a researcher to compare a subject protein or nucleotide sequence (called a query) with a library or database of sequences, and identify database sequences that resemble alphabet above a certain threshold. For example, following the discovery of a previously unknown gene in the mouse, a scientist will typically perform a BLAST search of the human genome to see if humans carry a similar gene; BLAST will identify sequences in the pig genome that resemble the mouse gene based on similarity of sequence. Background BLAST, which ''The New York Times'' called ''the Google of biological research'', is one of the most widely used bioinformatics programs for sequence searching. It addresses a fundamental problem in bioinformatics r ...
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Non-motile Bacteria
Non-motile bacteria are bacteria species that lack the ability and structures that would allow them to propel themselves, under their own power, through their environment. When non-motile bacteria are cultured in a stab tube, they only grow along the stab line. If the bacteria are mobile, the line will appear diffuse and extend into the medium. The cell structures that provide the ability for locomotion are the cilia and flagella. Coliform and Streptococci are examples of non-motile bacteria as are ''Klebsiella pneumoniae'', and ''Yersinia pestis''. Motility is one characteristic used in the identification of bacteria and evidence of possessing structures: peritrichous flagella, polar flagella and/or a combination of both. Though the lack of motility might be regarded a disadvantage, some non-motile bacteria possess structures that allow their attachment to eukaryotic cells, like GI mucousal cells. Vancomycin resistant Enterococcus spp. are non-motile while vancomycin susceptib ...
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Phenotype
In genetics, the phenotype () is the set of observable characteristics or traits of an organism. The term covers the organism's morphology or physical form and structure, its developmental processes, its biochemical and physiological properties, its behavior, and the products of behavior. An organism's phenotype results from two basic factors: the expression of an organism's genetic code, or its genotype, and the influence of environmental factors. Both factors may interact, further affecting phenotype. When two or more clearly different phenotypes exist in the same population of a species, the species is called polymorphic. A well-documented example of polymorphism is Labrador Retriever coloring; while the coat color depends on many genes, it is clearly seen in the environment as yellow, black, and brown. Richard Dawkins in 1978 and then again in his 1982 book ''The Extended Phenotype'' suggested that one can regard bird nests and other built structures such as cad ...
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Actinomycosis
Actinomycosis is a rare infectious bacterial disease caused by ''Actinomyces'' species. The name refers to ray-like appearance of the organisms in the granules. About 70% of infections are due to either ''Actinomyces israelii'' or '' A. gerencseriae''. Infection can also be caused by '' Streptomyces somaliensis'' and '' Propionibacterium propionicus''. The condition is likely to be a polymicrobial anaerobic infection. Signs and symptoms The disease is characterised by the formation of painful abscesses in the mouth, lungs, breast, or gastrointestinal tract. Actinomycosis abscesses grow larger as the disease progresses, often over months. In severe cases, they may penetrate the surrounding bone and muscle to the skin, where they break open and leak large amounts of pus, which often contains characteristic granules filled with progeny bacteria. These granules are often called "sulfur granules" due to their yellow appearance, although they may also be white, gray or brown. Causes ...
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Mucosal Surfaces
A mucous membrane or mucosa is a membrane that lines various cavities in the body of an organism and covers the surface of internal organs. It consists of one or more layers of epithelial cells overlying a layer of loose connective tissue. It is mostly of endodermal origin and is continuous with the skin at body openings such as the eyes, eyelids, ears, inside the nose, inside the mouth, lips, the genital areas, the urethral opening and the anus. Some mucous membranes secrete mucus, a thick protective fluid. The function of the membrane is to stop pathogens and dirt from entering the body and to prevent bodily tissues from becoming dehydrated. Structure The mucosa is composed of one or more layers of epithelial cells that secrete mucus, and an underlying lamina propria of loose connective tissue. The type of cells and type of mucus secreted vary from organ to organ and each can differ along a given tract. Mucous membranes line the digestive, respiratory and reproductive tracts ...
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Whole Genome Sequencing
Whole genome sequencing (WGS), also known as full genome sequencing, complete genome sequencing, or entire genome sequencing, is the process of determining the entirety, or nearly the entirety, of the DNA sequence of an organism's genome at a single time. This entails sequencing all of an organism's chromosomal DNA as well as DNA contained in the mitochondrial DNA, mitochondria and, for plants, in the chloroplast. Whole genome sequencing has largely been used as a research tool, but was being introduced to clinics in 2014. In the future of personalized medicine, whole genome sequence data may be an important tool to guide therapeutic intervention. The tool of DNA sequencing, gene sequencing at Single-nucleotide polymorphism, SNP level is also used to pinpoint functional variants from association studies and improve the knowledge available to researchers interested in evolutionary biology, and hence may lay the foundation for predicting disease susceptibility and drug response. ...
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Actinomyces Israelii
''Actinomyces israelii'' is a species of Gram-positive, rod-shaped bacteria within the genus ''Actinomyces''. Known to live commensally on and within humans, ''A. israelii'' is an opportunistic pathogen and a cause of actinomycosis. Many physiologically diverse strains of the species are known to exist, though not all are strict anaerobes. It was named after the German surgeon James Adolf Israel (1848–1926), who studied the organism for the first time in 1878. Pathogenesis Actinomycosis is most frequently caused by ''A. israelii''. It is a normal colonizer of the vagina, colon, and mouth. Infection is established first by a breach of the mucosal barrier during various procedures (dental, gastrointestinal), aspiration, or pathologies such as diverticulitis Diverticulitis, specifically colonic diverticulitis, is a gastrointestinal disease characterized by inflammation of abnormal pouches—diverticula—which can develop in the wall of the large intestine. Symptoms t ...
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Actinomyces Gerencseriae
''Actinomyces gerencseriae'' is a species in the genus ''Actinomyces'' once known as ''Actinomyces israelii'' serovar II. ''A. gerencseriae'' was named for bacteriologist A bacteriologist is a microbiologist, or similarly trained professional, in bacteriology -- a subdivision of microbiology that studies bacteria, typically pathogenic ones. Bacteriologists are interested in studying and learning about bacteria, ... Mary Ann Gerencser. References External linksType strain of ''Actinomyces gerencseriae'' at Bac''Dive'' - the Bacterial Diversity Metadatabase External links Type strain of ''Actinomyces gerencseriae'' at Bac''Dive'' - the Bacterial Diversity Metadatabase Actinomycetales Gram-positive bacteria Bacteria described in 1990 {{actinobacteria-stub ...
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Actinomycetaceae
The Actinomycetaceae (often called actinomycetes or mycelial bacteria) are a family of bacteria in the order Actinomycetales that contains the medically important genus ''Actinomyces''. These organisms are closely related to the mycobacteria, but were originally classified as fungi because they were thought to be transitional forms between bacteria and fungi. Genera The family ''Actinomycetaceae'' comprises the following genera: * '' Actinobaculum'' Lawson et al. 1997 * "'' Actinomonospora''" Castellani et al. 1959 * ''Actinomyces'' Harz 1877 (Approved Lists 1980) * '' Actinotignum'' Yassin et al. 2015 * "'' Ancrocorticia''" Xu et al. 2019 * ''Arcanobacterium'' Collins et al. 1983 * '' Boudabousia'' Nouioui et al. 2018 * '' Bowdeniella'' corrig. Nouioui et al. 2018 * '' Buchananella'' Nouioui et al. 2018 * '' Flaviflexus'' Du et al. 2013 * '' Fudania'' Zhu et al. 2019 * '' Gleimia'' Nouioui et al. 2018 * ''Mobiluncus'' Spiegel and Roberts 1984 * "'' Neoactinobaculum''" Belkace ...
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Actinomycetales
The Actinomycetales is an order of Actinomycetota. A member of the order is often called an actinomycete. Actinomycetales are generally gram-positive and anaerobic and have mycelia in a filamentous and branching growth pattern. Some actinomycetes can form rod- or coccoid-shaped forms, while others can form spores on aerial hyphae. Actinomycetales bacteria can be infected by bacteriophages, which are called actinophages. Actinomycetales can range from harmless bacteria to pathogens with resistance to antibiotics. Reproduction Actinomycetales have 2 main forms of reproduction: spore formation and hyphae fragmentation. During reproduction, Actinomycetales can form conidiophores, sporangiospores, and oidiospores. In reproducing through hyphae fragmentation, the hyphae formed by Actinomycetales can be a fifth to half the size of fungal hyphae, and bear long spore chains. Presence and associations Actinomycetales can be found mostly in soil and decaying organic matter, as well as in ...
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Actinomycetota
The ''Actinomycetota'' (or ''Actinobacteria'') are a phylum of all gram-positive bacteria. They can be terrestrial or aquatic. They are of great economic importance to humans because agriculture and forests depend on their contributions to soil systems. In soil they help to decompose the organic matter of dead organisms so the molecules can be taken up anew by plants. While this role is also played by fungi, ''Actinomycetota'' are much smaller and likely do not occupy the same ecological niche. In this role the colonies often grow extensive mycelia, like a fungus would, and the name of an important order of the phylum, '' Actinomycetales'' (the actinomycetes), reflects that they were long believed to be fungi. Some soil actinomycetota (such as ''Frankia'') live symbiotically with the plants whose roots pervade the soil, fixing nitrogen for the plants in exchange for access to some of the plant's saccharides. Other species, such as many members of the genus '' Mycobacterium'', ar ...
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