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AP7 (pension Fund)
AP7 or AP-7 may refer to: * 2022 AP7, an asteroid * AP-7 (drug), an NMDA receptor antagonist * Autopista AP-7 The ''Autopista AP-7'' (also called ''Autopista del MediterrĂ¡neo'') ( ca, Autopista de la MediterrĂ nia) is a Spanish Highways in Spain, autopista (controlled-access highway). It runs along the Mediterranean coast of Spain. AP-7 has two differ ...
, a motorway in Spain * , a 1919 US Navy troop transport and hospital ship {{Letter-NumberCombDisambig ...
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2022 AP7
is a kilometer-sized Apollo asteroid and potentially hazardous object orbiting between Venus and Jupiter. It was discovered on 13 January 2022 by Scott Sheppard at Cerro Tololo Observatory. Based on its absolute magnitude (H), is likely the largest potentially hazardous object identified in the eight years prior to its 2022 discovery. Discovery was discovered as part of Sheppard's twilight survey for near-Earth asteroids interior to Earth and Venus, using Cerro Tololo Observatory's Dark Energy Camera. Notable discoveries from this survey include the Atira asteroids and , the latter of which holds the record for the shortest orbital period of any known asteroid . Orbit and classification is considered "potentially hazardous" only because of its large size and low Earth minimum orbit intersection distance (MOID) just within . However, the asteroid does not currently make notable close approaches to Earth because it is in a 1:5 near orbital resonance with Earth, which ...
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AP-7 (drug)
AP-7 is a selective NMDA receptor (NMDAR) antagonist that competitively inhibits the glutamate binding site and thus activation of NMDAR. It has anticonvulsant Anticonvulsants (also known as antiepileptic drugs or recently as antiseizure drugs) are a diverse group of pharmacological agents used in the treatment of epileptic seizures. Anticonvulsants are also increasingly being used in the treatment of b ... effects. AP-7 functions specifically as a NMDA recognition site blocker, in contrast with 7-chlorokynurenate, which acts as a glycine site modulation blocker. Animal studies AP-7 injected directly into the dorsal periaqueductal grey (DPAG) of rats produced an anxiolytic effect, whereas direct injection outside of the DPAG did not elicit anxiolytic effects. This suggests that a portion of systemically taken NMDA antagonist's anxiolytic effects comes from the DPAG region of the brain, at least in rats. The DPAG of the brain is thought to deal with fear-like defensive beha ...
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