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ACSF3
Acyl-CoA synthetase family member 3 is an enzyme that in humans is encoded by the ''ACSF3'' gene. The enzyme belongs to the Acyl-CoA synthetase, acyl-CoA synthetase family. Structure The ''ACSF3'' gene is located on the Chromosome 16, 16th chromosome, with its specific location being 16q24.3. The gene contains 17 Exon, exons. ''ACSF3'' encodes a 64.1 kDa protein that is composed of 576 Amino acid, amino acids; 20 Peptide, peptides have been observed through mass spectrometry data. Function This gene encodes a member of the Acyl-CoA synthetase, acyl-CoA synthetase family of enzymes that activate fatty acids by catalyzing the formation of a thioester linkage between Fatty acid, fatty acids and coenzyme A. The encoded protein is localized to mitochondria, has high specificity for Malonic acid, malonate and Methylmalonic acid, methylmalonate and possesses Malonate—CoA ligase, malonyl-CoA synthetase activity: :Adenosine triphosphate, ATP + Malonic acid, malonate + Coenzyme A, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Malonate—CoA Ligase
In enzymology, a malonate—CoA ligase (), also known as malonyl-CoA synthetase or malonate:CoA ligase (AMP-forming), is an enzyme that catalysis, catalyzes the chemical reaction: :ATP + malonate + CoA \rightleftharpoons AMP + diphosphate + malonyl-CoA The 3 substrate (biochemistry), substrates of this enzyme are adenosine triphosphate, ATP, malonate, and coenzyme A, CoA, whereas its 3 product (chemistry), products are adenosine monophosphate, AMP, diphosphate, and malonyl-CoA. This enzyme belongs to the class of ligases, specifically those forming Carbon-sulfur bond, carbon-sulfur bonds as acid-thiol ligases or, more precisely, to the family of Acyl-CoA synthetase, acyl-CoA synthetases. This enzyme participates in mitochondrial fatty acid synthesis metabolism. Examples The following enzymes with malonyl-CoA synthetase activity are known: Acyl-CoA synthetase family member 3 (ACSF3) The only known malonyl-CoA synthetase in Mammal, mammals is the Mitochondrion, mitochondrial ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |