A. V. Apkarian
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A. V. Apkarian
Apkar Vania Apkarian is a professor of physiology, anesthesiology, and physical medicine and rehabilitation at Northwestern University in the Feinberg School of Medicine. He has been a pioneer in the use of Magnetic resonance spectroscopy to study the neurochemistry of the brain and the development of novel analytical approaches to studying consciousness, including the first demonstration of the brain's small-world network properties using fMRI. In 2008, Dr. Apkarian proposed the theory that chronic pain is a form of emotional learning, which popularized the study of reward learning within the pain research field. Dr. Apkarian earned a master's degree in electrical engineering from the University of Southern California and earned a Ph.D. in neuroscience from the State University of New York Upstate Medical University in Syracuse, New York. He is the brother of Vartkess A. Apkarian, a noted chemical physicist and laser spectroscopist at University of California at Irvine. ...
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Physiology
Physiology (; ) is the scientific study of functions and mechanisms in a living system. As a sub-discipline of biology, physiology focuses on how organisms, organ systems, individual organs, cells, and biomolecules carry out the chemical and physical functions in a living system. According to the classes of organisms, the field can be divided into medical physiology, animal physiology, plant physiology, cell physiology, and comparative physiology. Central to physiological functioning are biophysical and biochemical processes, homeostatic control mechanisms, and communication between cells. ''Physiological state'' is the condition of normal function. In contrast, ''pathological state'' refers to abnormal conditions, including human diseases. The Nobel Prize in Physiology or Medicine is awarded by the Royal Swedish Academy of Sciences for exceptional scientific achievements in physiology related to the field of medicine. Foundations Cells Although there are differ ...
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University Of California At Irvine
The University of California, Irvine (UCI or UC Irvine) is a public land-grant research university in Irvine, California. One of the ten campuses of the University of California system, UCI offers 87 undergraduate degrees and 129 graduate and professional degrees, and roughly 30,000 undergraduates and 6,000 graduate students are enrolled at UCI as of Fall 2019. The university is classified among " R1: Doctoral Universities – Very high research activity", and had $436.6 million in research and development expenditures in 2018. UCI became a member of the Association of American Universities in 1996. The university was rated as one of the "Public Ivies” in 1985 and 2001 surveys comparing publicly funded universities the authors claimed provide an education comparable to the Ivy League. The university also administers the UC Irvine Medical Center, a large teaching hospital in Orange, and its affiliated health sciences system; the University of California, Irvine, Arboretum; and ...
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Placebo
A placebo ( ) is a substance or treatment which is designed to have no therapeutic value. Common placebos include inert tablets (like sugar pills), inert injections (like Saline (medicine), saline), sham surgery, and other procedures. In general, placebos can affect how patients perceive their condition and encourage the body's chemical processes for relieving pain and a few other symptoms, but have no impact on the disease itself. Improvements that patients experience after being treated with a placebo can also be due to unrelated factors, such as regression to the mean (a statistical effect where an unusually high or low measurement is likely to be followed by a less extreme one). The use of placebos in clinical medicine raises ethical concerns, especially if they are disguised as an active treatment, as this introduces dishonesty into the doctor–patient relationship and bypasses informed consent. While it was once assumed that this deception was necessary for placebos to have ...
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Yale School Of Medicine
The Yale School of Medicine is the graduate medical school at Yale University, a private research university in New Haven, Connecticut. It was founded in 1810 as the Medical Institution of Yale College and formally opened in 1813. The primary teaching hospital for the school is Yale New Haven Hospital. The school is home to the Harvey Cushing/John Hay Whitney Medical Library, one of the largest modern medical libraries which is known for its historical collections. The faculty includes 70 National Academy of Sciences members, 47 National Academy of Medicine members, and 13 Howard Hughes Medical Institute investigators. '' U.S. News & World Report'' currently ranks the Yale School of Medicine 10th in the country for research and 59th in primary care. The MD program is highly selective; for the class of 2022, the school received 4,968 applications to fill 104 seats. The median GPA for the class was 3.89, and the median MCAT was 521. Education The School of Medicine offers the Doc ...
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Paul Geha
Paul may refer to: * Paul (given name), a given name (includes a list of people with that name) * Paul (surname), a list of people People Christianity *Paul the Apostle (AD c.5–c.64/65), also known as Saul of Tarsus or Saint Paul, early Christian missionary and writer * Pope Paul (other), multiple Popes of the Roman Catholic Church * Saint Paul (other), multiple other people and locations named "Saint Paul" Roman and Byzantine empire * Lucius Aemilius Paullus Macedonicus (c. 229 BC – 160 BC), Roman general * Julius Paulus Prudentissimus (), Roman jurist * Paulus Catena (died 362), Roman notary * Paulus Alexandrinus (4th century), Hellenistic astrologer * Paul of Aegina or Paulus Aegineta (625–690), Greek surgeon Royals *Paul I of Russia (1754–1801), Tsar of Russia * Paul of Greece (1901–1964), King of Greece Other people *Paul the Deacon or Paulus Diaconus (c. 720 – c. 799), Italian Benedictine monk *Paul (father of Maurice), the father of Maur ...
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Rehabilitation Institute Of Chicago
The Shirley Ryan AbilityLab, formerly the Rehabilitation Institute of Chicago (RIC), is a not-for-profit nationally ranked physical medicine and rehabilitation research hospital based in Chicago, Illinois. Founded in 1954, the AbilityLab is designed for patient care, education, and research in physical medicine and rehabilitation (PM&R). The AbilityLab specializes in rehabilitation for adults and children with the most severe, complex conditions ranging from traumatic brain and spinal cord injury to stroke, amputation and cancer-related impairment. Affiliated with Northwestern University, the hospital is located on Northwestern’s Chicago campus and partners on research and medical efforts. Since 1991, the hospital has remained the top ranked rehabilitation hospital in America as ranked by '' U.S. News & World Report''. Applied research focuses in the areas of neuroscience, bionic medicine, musculoskeletal medicine and technology transfer. Upon opening in March 2017, its 1.2- ...
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Shirley Ryan Ability Lab
Shirley may refer to: Arts and entertainment * ''Shirley'' (novel), an 1849 novel by Charlotte Brontë * ''Shirley'' (1922 film), a British silent film * ''Shirley'' (2020 film), an American film * ''Shirley'' (album), a 1961 album by Shirley Bassey * "Shirley" (song), a 1958 song by John Fred and the Playboys * ''Shirley'' (TV series), a 1979 TV series People * Shirley (name), a given name and a surname *Shirley (Danish singer) (born 1976) * Shirley (Dutch singer) (born 1946), Dutch singer and pianist Places United Kingdom * Shirley, Derbyshire, England * Shirley, New Forest, a location near Bransgore in Hampshire *Shirley, Southampton, a district of Southampton, Hampshire, England * Shirley, London, in Croydon *Shirley, West Midlands, England United States *Shirley, Arkansas *Shirley, Illinois * Shirley, Indiana *Shirley, Maine * Shirley, Massachusetts, a New England town **Shirley (CDP), Massachusetts, the main village in the town * Shirley, Minnesota * Shirley, Missouri * S ...
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Marwan Baliki
Marwan, Merwan or Mervan ( ar, مروان ''marwān''), is an Arabic male given name derived from the word ''marū/ maruw'' (مرو) with the meaning of either minerals, " flint(-stone)", " quartz" or "a hard stone of nearly pure silica". However, the Arabic name for quartz is ''ṣawwān'' (صَوَّان). The name is also the name of a type of genus of the herbal plant basil. Variants include Merouane / Marouane / Marouan. Feminine forms of the name include Marwa / Marwah and Marwana/ Marwanah (مروانة ''marwānah''). Notable persons with these names include: Given name Marwan * Marwan I, Umayyad caliph (r. 684–685) * Marwan II, Umayyad caliph ( r. 744–750) *Marwan ibn Abi Hafsa (d. 797), Abbasid-era poet *Marwan (rapper), Danish-Palestinian rapper Mohamed Marwan * Marwan Ali, Tunisian pop singer * Marwan Barghouti, leader of the Palestinian group Fatah *Marwan Charbel, Lebanese general and politician *Marwan Dudin (1936–2016), Jordanian politician * Marwan ...
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Nucleus Accumbens
The nucleus accumbens (NAc or NAcc; also known as the accumbens nucleus, or formerly as the ''nucleus accumbens septi'', Latin for "nucleus adjacent to the septum") is a region in the basal forebrain rostral to the preoptic area of the hypothalamus. The nucleus accumbens and the olfactory tubercle collectively form the ventral striatum. The ventral striatum and dorsal striatum collectively form the striatum, which is the main component of the basal ganglia. The dopaminergic neurons of the mesolimbic pathway project onto the GABAergic medium spiny neurons of the nucleus accumbens and olfactory tubercle. Each cerebral hemisphere has its own nucleus accumbens, which can be divided into two structures: the nucleus accumbens core and the nucleus accumbens shell. These substructures have different morphology and functions. Different NAcc subregions (core vs shell) and neuron subpopulations within each region (D1-type vs D2-type medium spiny neurons) are responsible for different ...
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Medial Prefrontal Cortex
In mammalian brain anatomy, the prefrontal cortex (PFC) covers the front part of the frontal lobe of the cerebral cortex. The PFC contains the Brodmann areas BA8, BA9, BA10, BA11, BA12, BA13, BA14, BA24, BA25, BA32, BA44, BA45, BA46, and BA47. The basic activity of this brain region is considered to be orchestration of thoughts and actions in accordance with internal goals. Many authors have indicated an integral link between a person's will to live, personality, and the functions of the prefrontal cortex. This brain region has been implicated in executive functions, such as planning, decision making, short-term memory, personality expression, moderating social behavior and controlling certain aspects of speech and language. Executive function relates to abilities to differentiate among conflicting thoughts, determine good and bad, better and best, same and different, future consequences of current activities, working toward a defined goal, prediction of outcomes, e ...
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Functional Connectivity
Resting state fMRI (rs-fMRI or R-fMRI) is a method of functional magnetic resonance imaging (fMRI) that is used in brain mapping to evaluate regional interactions that occur in a resting or task-negative state, when an explicit task is not being performed. A number of resting-state brain networks have been identified, one of which is the default mode network. These brain networks are observed through changes in blood flow in the brain which creates what is referred to as a blood-oxygen-level dependent (BOLD) signal that can be measured using fMRI. Because brain activity is intrinsic, present even in the absence of an externally prompted task, any brain region will have spontaneous fluctuations in BOLD signal. The resting state approach is useful to explore the brain's functional organization and to examine if it is altered in neurological or mental disorders. Because of the resting state aspect of this imaging, data can be collected from a range of patient groups including peop ...
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Qualia
In philosophy of mind, qualia ( or ; singular form: quale) are defined as individual instances of subjective, conscious experience. The term ''qualia'' derives from the Latin neuter plural form (''qualia'') of the Latin adjective '' quālis'' () meaning "of what sort" or "of what kind" in a specific instance, such as "what it is like to taste a specific this particular apple now". Examples of qualia include the perceived sensation of ''pain'' of a headache, the ''taste'' of wine, as well as the ''redness'' of an evening sky. As qualitative characters of sensation, qualia stand in contrast to propositional attitudes, where the focus is on beliefs about experience rather than what it is directly like to be experiencing. Philosopher and cognitive scientist Daniel Dennett once suggested that ''qualia'' was "an unfamiliar term for something that could not be more familiar to each of us: the ways things seem to us". Much of the debate over their importance hinges on the definition ...
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