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4F-PHP
4-Fluoro-alpha-PHP (4F-PHP) is a recreational designer drug from the substituted cathinone family with stimulant effects, which first appeared on the illicit market in around 2017. See also * α-PHP * 3F-PVP * 3F-NEH * 3F-PiHP * 4F-PVP * 4Cl-PVP * 4F-POP * MFPVP * MDPHP * N-Ethylhexedrone * N-Ethylhexylone ''N''-Ethylhexylone is a recreational designer drug from the substituted cathinone family, with stimulant effects. It was first identified in Poland in August 2019. It is illegal in Taiwan since July 2020, where it had been sold mixed with plant ... References Pyrrolidinophenones Designer drugs Fluoroarenes {{nervous-system-drug-stub ...
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α-PHP
α-Pyrrolidinohexiophenone (α-PHP, A-PHP, Aphp, alpha-PHP, α-Pyrrolidinohexanophenone, PV-7) is a synthetic stimulant drug of the cathinone class developed in the 1960s which has been reported as a novel designer drug. Similar chemical compounds α-Pyrrolidinohexiophenone is a longer chain homologue of α-PVP, having an extra carbon on the alkyl side chain. Regarding the potency of alpha-PHP in the brain, chemist Michael H. Baumann of the Designer Drug Research Unit (established by Baumann) of the National Institute on Drug Abuse stated: "alpha-PHP might be even more potent than alpha-PVP"; this statement is based on laboratory tests of chemical reactivity. Pyrovalerone is a structural isomer of alpha-PHP. Legality In the United States, α-PHP in the past has been assigned to Schedule I on a Temporary Placement basis, although the order has expired without renewal or permanent placement and is no longer Scheduled at the Federal level as of July 2021. Despite this however, ...
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3F-PVP
3-Fluoro-alpha-PVP (3F-PVP) is a recreational designer drug from the substituted cathinone family with stimulant effects, which first appeared on the illicit market in around 2018. It is illegal in Finland. See also * 3-Fluoroamphetamine * 3-Fluoromethamphetamine * 3-Fluoroethamphetamine * 3-Fluoromethcathinone * 3-Fluorophenmetrazine * 3F-NEH * 3F-PiHP * 4F-PVP * 4Cl-PVP 4-Chloro-''alpha''-pyrrolidinovalerophenone (also known as 4-chloro-''alpha''-pyrrolidinopentiophenone, 4-chloro-α-PVP, 4Cl-PVP, or 4C-PVP) is an emerging recreational designer drug of the pyrrolidinophenone class, similar in structure to ''al ... * 4F-PHP References Pyrrolidinophenones Designer drugs Serotonin-norepinephrine-dopamine releasing agents {{nervous-system-drug-stub ...
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3F-PiHP
3F-PiHP (3F-α-PHiP) is a recreational designer drug from the substituted cathinone family, with stimulant effects. It was first identified in both Sweden and Finland in mid-2019, and was made illegal in Finland in August 2019. See also * 3-Fluoromethcathinone * 3F-NEH * 3F-PVP * 4F-PHP * α-PHiP * α-PCyP * Isohexylone Isohexylone is a recreational designer drug from the substituted cathinone family, with stimulant effects. It was first identified in the United Kingdom in June 2019. See also * Methylone * 5-Methylethylone * Butylone * Desmethylsibutramine * ... References Pyrrolidinophenones Designer drugs Serotonin-norepinephrine-dopamine releasing agents Fluoroarenes {{pharm-stub ...
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MFPVP
MFPVP (3-Methyl-4-fluoro-α-pyrrolidinovalerophenone) is a recreational designer drug from the substituted cathinone family, with stimulant effects. It was first identified in Sweden in April 2020. See also * 3F-PVP * 4F-PVP * 4F-PHP * 4Cl-PVP * 4-Cl-3-MMC * MOPVP * DMPVP * MDPV * O-2390 * Pyrovalerone (Centroton, 4-Methyl-β-keto-prolintane, Thymergix, O-2371) is a psychoactive drug with stimulant effects via acting as a norepinephrine-dopamine reuptake inhibitor (NDRI), and is used for the clinical treatment of chronic fatigue or letharg ... References Pyrrolidinophenones Designer drugs {{nervous-system-drug-stub ...
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N-Ethylhexylone
''N''-Ethylhexylone is a recreational designer drug from the substituted cathinone family, with stimulant effects. It was first identified in Poland in August 2019. It is illegal in Taiwan since July 2020, where it had been sold mixed with plant material under the name 彩虹菸 ("Rainbow Tobacco" or "Rainbow Smoke"). See also * 3F-NEH * 4F-PHP * 5-Methylethylone * Ethylone * Eutylone * Ephylone * Isohexylone * MDPV * MDPHP * N-Ethylhexedrone * N-Ethylheptylone ''N''-Ethylheptylone (HEP) is a recreational designer drug from the substituted cathinone family, with stimulant effects. It is a homologue of related drugs such as ethylone, eutylone, ephylone and ''N''-ethylhexylone but with a longer hepty ... References Cathinones Designer drugs Norepinephrine–dopamine reuptake inhibitors {{nervous-system-drug-stub ...
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Designer Drug
A designer drug is a structural or functional analog of a controlled substance that has been designed to mimic the pharmacological effects of the original drug, while avoiding classification as illegal and/or detection in standard drug tests. Designer drugs include psychoactive substances that have been designated by the European Union as new psychoactive substances (NPS) as well as analogs of performance-enhancing drugs such as designer steroids. Some of these were originally synthesized by academic or industrial researchers in an effort to discover more potent derivatives with fewer side effects, and shorter duration (and possibly also because it is easier to apply for patents for new molecules) and were later co-opted for recreational use. Other designer drugs were prepared for the first time in clandestine laboratories. Because the efficacy and safety of these substances have not been thoroughly evaluated in animal and human trials, the use of some of these drugs may result i ...
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Substituted Cathinone
Substituted cathinones, which include some stimulants and entactogens, are derivatives of cathinone. They feature a phenethylamine core with an alkyl group attached to the alpha carbon, and a ketone group attached to the beta carbon, along with additional substitutions. Cathinone occurs naturally in the plant khat whose leaves are chewed as a recreational drug. List of substituted cathinones The derivatives may be produced by substitutions at four locations of the cathinone molecule: * R1 = hydrogen, or any combination of one or more alkyl, alkoxy, alkylenedioxy, haloalkyl or halide substituents * R2 = hydrogen or any alkyl group * R3 = hydrogen, any alkyl group, or incorporation in a cyclic structure * R4 = hydrogen, any alkyl group, or incorporation in a cyclic structure The following table displays notable derivatives that have been reported: Legality On 2 April 2010, the Advisory Council on the Misuse of Drugs in the UK announced that a broad structure-based ba ...
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Stimulant
Stimulants (also often referred to as psychostimulants or colloquially as uppers) is an overarching term that covers many drugs including those that increase activity of the central nervous system and the body, drugs that are pleasurable and invigorating, or drugs that have Sympathomimetic drug, sympathomimetic effects. Stimulants are widely used throughout the world as prescription medicines as well as without a prescription (either legally or Prohibition (drugs), illicitly) as performance-enhancing substance, performance-enhancing or recreational drug use, recreational drugs. Among narcotics, stimulants produce a noticeable crash or ''Comedown (drugs), comedown'' at the end of their effects. The most frequently prescribed stimulants as of 2013 were lisdexamfetamine (Vyvanse), methylphenidate (Ritalin), and amphetamine (Adderall). It was estimated in 2015 that the percentage of the world population that had used cocaine during a year was 0.4%. For the category "amphetamines and p ...
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3F-NEH
3F-NEH (3-Fluoro-N-Ethylhexedrone) is a recreational designer drug from the substituted cathinone family, with stimulant effects. It was first identified in Sweden in October 2020. See also * 3-Fluoromethamphetamine * 3-Fluoromethcathinone * 3F-NEB * 3F-PiHP * 3F-PVP * 3F-Phenmetrazine * N-Ethylhexedrone * N-Ethylhexylone ''N''-Ethylhexylone is a recreational designer drug from the substituted cathinone family, with stimulant effects. It was first identified in Poland in August 2019. It is illegal in Taiwan since July 2020, where it had been sold mixed with plant ... References Cathinones Designer drugs Serotonin-norepinephrine-dopamine releasing agents Fluoroarenes {{nervous-system-drug-stub ...
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4Cl-PVP
4-Chloro-''alpha''-pyrrolidinovalerophenone (also known as 4-chloro-''alpha''-pyrrolidinopentiophenone, 4-chloro-α-PVP, 4Cl-PVP, or 4C-PVP) is an emerging recreational designer drug of the pyrrolidinophenone class, similar in structure to ''alpha''-pyrrolidinopentiophenone (α-PVP). The pharmacology and toxicity of this compound is unknown, though it is presumed to be a stimulant drug. In the United States, 4-chloro-α-PVP is a Schedule I Controlled Substance. See also * 3F-PVP * 4-Chloromethcathinone * 4F-PVP * 4-Et-PVP * MFPVP * MOPVP * DMPVP * MDPV * O-2390 * Pyrovalerone * RTI-31 (–)-2β-Carbomethoxy-3β-(4'-chlorophenyl)tropane (RTI-''4229''-31) is a synthetic analog of cocaine that acts as a stimulant. Semi-synthesis of this compound is dependent upon the availability of cocaine starting material. According to the ar ... References Pyrrolidinophenones Designer drugs Serotonin-norepinephrine-dopamine releasing agents Propyl compounds {{DEFAULTSORT ...
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