2018 Malaysia HFMD Outbreak
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2018 Malaysia HFMD Outbreak
Beginning in January 2018, an outbreak of hand, foot, and mouth disease (HFMD) occurred among children nationwide across Malaysia. Nearly 38,000 cases were recorded between January 1 and July 26, and by August 14 the total number of cases had risen to 51,000. Among the states and federal territories affected by the outbreak, Selangor recorded the highest cases with 11,349, Kuala Lumpur with 4,428 and Sarawak with 4,412 cases as reported in July 2018. At least two children in Sarawak and Penang died from complications caused by the virus. Background and history HFMD transmission outbreak in Malaysia was first reported in the state of Sarawak in 1997 where between 28 and 31 children died as a result of infection by the Enterovirus 71 (EV-A71) virus. Since then, recurrent cyclical epidemics of HFMD have occurred in the country every two to three years. While the root cause behind the recurrence of the disease remains a mystery, another factor that has been identified as increasi ...
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Hand, Foot, And Mouth Disease
Hand, foot, and mouth disease (HFMD) is a common infection caused by a group of enteroviruses. It typically begins with a fever and feeling generally unwell. This is followed a day or two later by flat discolored spots or bumps that may blister, on the hands, feet and mouth and occasionally buttocks and groin. Signs and symptoms normally appear 3–6 days after exposure to the virus. The rash generally resolves on its own in about a week. Fingernail and toenail loss may occur a few weeks later, but they will regrow with time. The viruses that cause HFMD are spread through close personal contact, through the air from coughing and the feces of an infected person. Contaminated objects can also spread the disease. Coxsackievirus A16 is the most common cause, and enterovirus 71 is the second-most common cause. Other strains of coxsackievirus and enterovirus can also be responsible. Some people may carry and pass on the virus despite having no symptoms of disease. Other anima ...
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Tachycardia
Tachycardia, also called tachyarrhythmia, is a heart rate that exceeds the normal resting rate. In general, a resting heart rate over 100 beats per minute is accepted as tachycardia in adults. Heart rates above the resting rate may be normal (such as with exercise) or abnormal (such as with electrical problems within the heart). Complications Tachycardia can lead to fainting. When the rate of blood flow becomes too rapid, or fast blood flow passes on damaged endothelium, it increases the friction within vessels resulting in turbulence and other disturbances. According to the Virchow's triad, this is one of the three conditions that can lead to thrombosis (i.e., blood clots within vessels). Causes Some causes of tachycardia include: * Adrenergic storm * Anaemia * Anxiety * Atrial fibrillation * Atrial flutter * Atrial tachycardia * Atrioventricular reentrant tachycardia * AV nodal reentrant tachycardia * Brugada syndrome * Circulatory shock and its various ca ...
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Oxford Academic
Oxford University Press (OUP) is the university press of the University of Oxford. It is the largest university press in the world, and its printing history dates back to the 1480s. Having been officially granted the legal right to print books by decree in 1586, it is the second oldest university press after Cambridge University Press. It is a department of the University of Oxford and is governed by a group of 15 academics known as the Delegates of the Press, who are appointed by the vice-chancellor of the University of Oxford. The Delegates of the Press are led by the Secretary to the Delegates, who serves as OUP's chief executive and as its major representative on other university bodies. Oxford University Press has had a similar governance structure since the 17th century. The press is located on Walton Street, Oxford, opposite Somerville College, in the inner suburb of Jericho. For the last 500 years, OUP has primarily focused on the publication of pedagogical texts and ...
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Enterovirus
''Enterovirus'' is a genus of positive-sense single-stranded RNA viruses associated with several human and mammalian diseases. Enteroviruses are named by their transmission-route through the intestine ('enteric' meaning intestinal). Serologic studies have distinguished 71 human enterovirus serotypes on the basis of antibody neutralization tests. Additional antigenic variants have been defined within several of the serotypes on the basis of reduced or nonreciprocal cross-neutralization between variant strains. On the basis of their pathogenesis in humans and animals, the enteroviruses were originally classified into four groups, polioviruses, Coxsackie A viruses (CA), Coxsackie B viruses (CB), and echoviruses, but it was quickly realized that there were significant overlaps in the biological properties of viruses in the different groups. Enteroviruses isolated more recently are named with a system of consecutive numbers: EV-D68, EV-B69, EV-D70, EV-A71, etc., where genotyping is ...
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Ministry Of Education (Malaysia)
The Ministry of Education ( ms, Kementerian Pendidikan) is a ministry of the Government of Malaysia that is responsible for education system, compulsory education, pre-tertiary education, technical and vocational education and training (TVET), curriculum standard, textbook, standardised test, language policy, translation, selective school, comprehensive school. Organisation * Minister of Education ** Deputy Minister of Education ** Second Deputy Minister of Education *** Secretary-General **** Under the Authority of Secretary-General ***** Internal Audit Division ***** Corporate Communication Unit ***** Key Performance Indicator Unit ***** Education Performance and Delivery Unit ***** Integrity Unit ***** Legal Advisor Office **** Deputy Secretary-General (Education Development) ***** Education Development Division ***** Procurement and Asset Management Division ***** Policy and International Relations Division ***** Scholarship Division ***** School Audit Division *** ...
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Singapore
Singapore (), officially the Republic of Singapore, is a sovereign island country and city-state in maritime Southeast Asia. It lies about one degree of latitude () north of the equator, off the southern tip of the Malay Peninsula, bordering the Strait of Malacca to the west, the Singapore Strait to the south, the South China Sea to the east, and the Straits of Johor to the north. The country's territory is composed of one main island, 63 satellite islands and islets, and one outlying islet; the combined area of these has increased by 25% since the country's independence as a result of extensive land reclamation projects. It has the third highest population density in the world. With a multicultural population and recognising the need to respect cultural identities of the major ethnic groups within the nation, Singapore has four official languages: English, Malay, Mandarin, and Tamil. English is the lingua franca and numerous public services are available only ...
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Johor
Johor (; ), also spelled as Johore, is a state of Malaysia in the south of the Malay Peninsula. Johor has land borders with the Malaysian states of Pahang to the north and Malacca and Negeri Sembilan to the northwest. Johor shares maritime borders with Singapore to the south and Indonesia to both the west and east. Johor Bahru is the capital city and the economic centre of the state, Kota Iskandar is the seat of the state government, and Muar serves as the royal town of the state. The old state capital is Johor Lama. As of 2020, the state's population is 4.01 million, making it the second most populated state in Malaysia. Johor has highly diverse tropical rainforests and an equatorial climate. The state's mountain ranges form part of the Titiwangsa Range, which is part of the larger Tenasserim Range connected to Thailand and Myanmar, with Mount Ophir being the highest point in Johor. While its state capital, Johor Bahru, which is located within Iskandar Malaysia devel ...
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Ministry Of Health (Malaysia)
The Ministry of Health ( ms, Kementerian Kesihatan), abbreviated MOH, is a ministry of the Government of Malaysia that is responsible for health system: health behaviour, cancer, public health, health management, medical research, health systems research, respiratory medicine, health promotion, healthcare tourism, medical device, blood collection, leprosy control, clinical research, health care, dental care, health institution, laboratory, pharmaceutical, patient safety. The Minister of Health administers ministerial functions through the Ministry of Health and a range of other government agencies. The current Health Minister is vacant following the resignation of the cabinet on the 16th of August 2021. The minister is assisted by the Deputy Minister of Health. Its headquarters is located in Putrajaya. Organisation * Minister of Health ** Deputy Minister *** Secretary-General **** Under the Authority of Secretary-General ***** Development Division ***** Policy a ...
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Pulse
In medicine, a pulse represents the tactile arterial palpation of the cardiac cycle (heartbeat) by trained fingertips. The pulse may be palpated in any place that allows an artery to be compressed near the surface of the body, such as at the neck ( carotid artery), wrist (radial artery), at the groin (femoral artery), behind the knee ( popliteal artery), near the ankle joint ( posterior tibial artery), and on foot (dorsalis pedis artery). Pulse (or the count of arterial pulse per minute) is equivalent to measuring the heart rate. The heart rate can also be measured by listening to the heart beat by auscultation, traditionally using a stethoscope and counting it for a minute. The radial pulse is commonly measured using three fingers. This has a reason: the finger closest to the heart is used to occlude the pulse pressure, the middle finger is used get a crude estimate of the blood pressure, and the finger most distal to the heart (usually the ring finger) is used to nullify ...
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Capillary Refill
Capillary refill time (CRT) is defined as the time taken for color to return to an external capillary bed after pressure is applied to cause blanching. It can be measured by holding a hand higher than heart-level and pressing the soft pad of a finger or fingernail until it turns white, then taking note of the time needed for the color to return once pressure is released. In humans, CRT of more than three seconds indicates decreased peripheral perfusion and may indicate cardiovascular or respiratory dysfunction. Assessment In adults CRT can be measured by applying pressure to the pad of a finger or toe for 5–10 seconds. It became popularized in the 1980s when Champion et al. proposed a CRT of less than 2 seconds be deemed normal and included CRT in the Trauma Score. The value of 2 seconds for a normal CRT that was proposed by Dr Champion had been arbitrarily chosen by his nurse, and no evidence supporting that value has subsequently been found. CRT has been shown to be influen ...
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Pallor
Pallor is a pale color of the skin that can be caused by illness, emotional shock or stress, stimulant use, or anemia, and is the result of a reduced amount of oxyhaemoglobin and may also be visible as pallor of the conjunctivae of the eyes on physical examination. Pallor is more evident on the face and palms. It can develop suddenly or gradually, depending on the cause. It is not usually clinically significant unless it is accompanied by a general pallor (pale lips, tongue, palms, mouth and other regions with mucous membranes). It is distinguished from similar presentations such as hypopigmentation (lack or loss of skin pigment) or simply a fair complexion. Causes * migraine attack or headache * excess estradiol and/or estrone * osteoporosis * emotional response, due to fear, embarrassment, grief, rage * anorexia * anemia, due to blood loss, poor nutrition, or underlying disease such as sickle cell anemia * iron deficiency * vitamin B12 deficiency * shock, a medical emergenc ...
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Cardiac Failure
Heart failure (HF), also known as congestive heart failure (CHF), is a syndrome, a group of signs and symptoms caused by an impairment of the heart's blood pumping function. Symptoms typically include shortness of breath, excessive fatigue, and leg swelling. The shortness of breath may occur with exertion or while lying down, and may wake people up during the night. Chest pain, including angina, is not usually caused by heart failure, but may occur if the heart failure was caused by a heart attack. The severity of the heart failure is measured by the severity of symptoms during exercise. Other conditions that may have symptoms similar to heart failure include obesity, kidney failure, liver disease, anemia, and thyroid disease. Common causes of heart failure include coronary artery disease, heart attack, high blood pressure, atrial fibrillation, valvular heart disease, excessive alcohol consumption, infection, and cardiomyopathy. These cause heart failure by altering the str ...
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