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2007 United Kingdom Foot-and-mouth Outbreak
The 2007 United Kingdom foot-and-mouth outbreak occurred when the discharge of infectious effluent from a laboratory in Surrey led to foot-and-mouth disease (FMD) infections at four nearby farms. The infections were detected via regular livestock testing by the Department for Environment, Food and Rural Affairs (Defra). The first diagnosis took place in a field of Normandy, Surrey; the second was three days later in a cattle-rotation field of a farm in Elstead, and the following day a third infection was found nearby within a quickly-established protection zone around the first detection. One month and ten days after the first diagnosis a final incidence of 2007 was identified and dealt with north of the first diseased animal. The source of the strain released and contained in Surrey in 2007 was the advanced effluent pipes from either the Institute for Animal Health or the similar vaccine researching and producing Merial Animal Health laboratory near to Pirbright village ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ppat
Amidophosphoribosyltransferase (ATase), also known as glutamine phosphoribosylpyrophosphate amidotransferase (GPAT), is an enzyme responsible for catalyzing the conversion of 5-phosphoribosyl-1-pyrophosphate (PRPP) into 5-phosphoribosyl-1-amine (PRA), using the amine group from a glutamine side-chain. This is the committing step in de novo purine synthesis. In humans it is encoded by the ''PPAT'' (phosphoribosyl pyrophosphate amidotransferase) gene. ATase is a member of the purine/pyrimidine phosphoribosyltransferase family. Structure and function The enzyme consists of two domains: a glutaminase domain that produces ammonia from glutamine by hydrolysis and a phosphoribosyltransferase domain that binds the ammonia to ribose-5-phosphate. Coordination between the two active sites of enzyme give it special complexity. The glutaminase domain is homologous to other N-terminal nucleophile (Ntn) hydrolases such as carbamoyl phosphate synthetase (CPSase). Nine invariant residues amo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
2001 United Kingdom Foot-and-mouth Crisis
The outbreak of foot-and-mouth disease in the United Kingdom in 2001 caused a crisis in British agriculture and tourism. This epizootic saw 2,000 cases of the disease in farms across most of the British countryside. Over 6 million cows and sheep were killed in an eventually successful attempt to halt the disease. Cumbria was the worst affected area of the country, with 893 cases. With the intention of controlling the spread of the disease, public rights of way across land were closed by order. This damaged the popularity of the Lake District as a tourist destination and led to the cancellation of that year's Cheltenham Festival, as well as the British Rally Championship for the 2001 season and delaying that year's general election by a month. Crufts, the dog-based festival had to be postponed by 2 months from March to May 2001. By the time that the disease was halted in October 2001, the crisis was estimated to have cost the United Kingdom £8bn. Background Britain's l ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Health & Safety Executive
The Health and Safety Executive (HSE) is a UK government agency responsible for the encouragement, regulation and enforcement of workplace health, safety and welfare, and for research into occupational risks in Great Britain. It is a non-departmental public body of the United Kingdom with its headquarters in Bootle, England. In Northern Ireland, these duties lie with the Health and Safety Executive for Northern Ireland. The HSE was created by the Health and Safety at Work etc. Act 1974, and has since absorbed earlier regulatory bodies such as the Factory Inspectorate and the Railway Inspectorate though the Railway Inspectorate was transferred to the Office of Rail and Road in April 2006. The HSE is sponsored by the Department for Work and Pensions. As part of its work, HSE investigates industrial accidents, small and large, including major incidents such as the explosion and fire at Buncefield in 2005. Though it formerly reported to the Health and Safety Commission, on 1 April ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Institute For Animal Health, Bakers Gate - Geograph
An institute is an organisational body created for a certain purpose. They are often research organisations ( research institutes) created to do research on specific topics, or can also be a professional body. In some countries, institutes can be part of a university or other institutions of higher education, either as a group of departments or an autonomous educational institution without a traditional university status such as a "university institute" (see Institute of Technology). In some countries, such as South Korea and India, private schools are sometimes referred to as institutes, and in Spain, secondary schools are referred to as institutes. Historically, in some countries institutes were educational units imparting vocational training and often incorporating libraries, also known as mechanics' institutes. The word "institute" comes from a Latin word ''institutum'' meaning "facility" or "habit"; from ''instituere'' meaning "build", "create", "raise" or "edu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Farmers Weekly
''Farmers Weekly'' is a magazine aimed at the British farming industry. It provides news; business features; a weekly digest of facts and figures about British, European and world agriculture; and livestock, arable and machinery sections with reports on technical developments, farm sales and analysis of prices. History and profile The first issue of ''The Farmers Weekly'' was on 22 June 1934, costing 2 d. It claimed to be a ''newspaper of the soil'' and aimed to increase agricultural production in the United Kingdom. It was acquired by Edward George Warris Hulton in 1937. The magazine is published weekly on Fridays, typically 51 times per year. ''Farmers Weekly'' has published books including ''Farmhouse Fare'' (1935) and ''Home Made Country Wines'' (1955), both consisting of recipes contributed by readers of the magazine. In the 1930s, ''Farmers Weekly'' average circulation per issue was 100,000 copies. In 2004, it had an average circulation of 77,233; by 2013, this had fall ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Belgium
Belgium, ; french: Belgique ; german: Belgien officially the Kingdom of Belgium, is a country in Northwestern Europe. The country is bordered by the Netherlands to the north, Germany to the east, Luxembourg to the southeast, France to the southwest, and the North Sea to the northwest. It covers an area of and has a population of more than 11.5 million, making it the 22nd most densely populated country in the world and the 6th most densely populated country in Europe, with a density of . Belgium is part of an area known as the Low Countries, historically a somewhat larger region than the Benelux group of states, as it also included parts of northern France. The capital and largest city is Brussels; other major cities are Antwerp, Ghent, Charleroi, Liège, Bruges, Namur, and Leuven. Belgium is a sovereign state and a federal constitutional monarchy with a parliamentary system. Its institutional organization is complex and is structured on both regional ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Merial
Boehringer Ingelheim Animal Health is a multinational animal health company, formed in January 2017 when Merial was acquired by Boehringer Ingelheim and merged with Boehringer Ingelheim's existing animal health assets. Overview In August 1997, Merial started as a joint venture between the animal health subsidiaries of Merck & Co. (MSD AgVet) and Sanofi-Aventis (Rhône-Mérieux). Merial became the animal health division of Sanofi, when Sanofi bought out Merck's 50% share of the joint venture. On December 30, 2016 Boehringer Ingelheim completed a swap of their OTC business for Sanofi's animal health business. Merial is now owned by Boehringer Ingelheim and combined with their animal health business, Boehringer Ingelheim Vetmedica, to form Boehringer Ingelheim Animal Health. Merial produces many products and vaccines for domestic pets, farm animals and wildlife. Merial has about 6,900 employees and is present in more than 150 countries in the world. Their sales in 2015 were about ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Foot-and-mouth Disease Virus
''Foot-and-mouth disease virus'' (FMDV) is the pathogen that causes foot-and-mouth disease. It is a picornavirus, the prototypical member of the genus ''Aphthovirus''. The disease, which causes vesicles (blisters) in the mouth and feet of cattle, pigs, sheep, goats, and other cloven-hoofed animals is highly infectious and a major plague of animal farming. Structure and genome The virus particle (25-30 nm) has an icosahedral capsid made of protein, without envelope, containing a positive-sense (mRNA sense) single-stranded ribonucleic acid (RNA) genome. Replication When the virus comes in contact with the membrane of a host cell, it binds to a receptor site and triggers a folding-in of the membrane. Once the virus is inside the host cell, the capsid dissolves, and the RNA gets replicated, and translated into viral proteins by the cell's ribosomes using a cap-independent mechanism driven by the internal ribosome entry site element. The synthesis of viral proteins ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Virus
A virus is a submicroscopic infectious agent that replicates only inside the living cells of an organism. Viruses infect all life forms, from animals and plants to microorganisms, including bacteria and archaea. Since Dmitri Ivanovsky's 1892 article describing a non-bacterial pathogen infecting tobacco plants and the discovery of the tobacco mosaic virus by Martinus Beijerinck in 1898,Dimmock p. 4 more than 9,000 virus species have been described in detail of the millions of types of viruses in the environment. Viruses are found in almost every ecosystem on Earth and are the most numerous type of biological entity. The study of viruses is known as virology, a subspeciality of microbiology. When infected, a host cell is often forced to rapidly produce thousands of copies of the original virus. When not inside an infected cell or in the process of infecting a cell, viruses exist in the form of independent particles, or ''virions'', consisting of (i) the genetic material, i. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Debby Reynolds
Deborah Reynolds Order of the Bath, CB served as the Chief Veterinary Officer (United Kingdom), Chief Veterinary Officer (CVO) of the United Kingdom from March 2004 until she retired in November 2007. She is usually referred to as Debby Reynolds, or less often as Deborah Reynolds. Chief Veterinary Officer Reynolds was the Chief Veterinary Officer (United Kingdom), Chief Veterinary Officer (CVO) of the United Kingdom and for the Department for Environment, Food and Rural Affairs (DEFRA) from March 2004 to 9 November 2007. As CVO, Reynolds was the United Kingdom, British government's main spokesperson on Veterinary medicine, animal health, and was in the British nationwide news repeatedly to explain policy and answer questions about outbreaks or control of serious animal infections, such as foot-and-mouth disease, H5N1, H5N1 bird flu, Mycobacterium bovis, bovine TB, rabies and Bluetongue disease, bluetongue virus. On 9 November 2007, DEFRA announced that Reynolds had opted to take ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chief Veterinary Officer (United Kingdom)
The Chief Veterinary Officer (or CVO) is an official in the British government, who is head of veterinary services in the United Kingdom. Wales, Scotland and Northern Ireland also each have a Chief Veterinary Officer. List of post holders for the United Kingdom The following people have held the post of Chief Veterinary Officer for the United Kingdom: *Alexander Curtis Cope, 1893–1905 *Sir Stewart Stockman, 1905–1926 *Sir James Joseph Ralph Jackson, 1926–1932 * Sir Percy John Luxton Kelland, 1932–1938 *Sir Daniel Alfred Edmond Cabot, 1938–1948 *Sir Thomas Dalling , 1948–1952 *Sir John Neish Ritchie, 1952–1965 *Mr John Reid, 1965–1970 *Mr A G Beynon, 1970–1973 *Mr A C L Brown, 1973–1980 *Mr William Howard Rees, August 1980 – May 1988 * Keith Meldrum, June 1988 – April 1997 * James Scudamore, April 1997 – March 2004 *Dr Debby Reynolds, March 2004 – November 2007 *Fred Landeg, November 2007 – May 2008 (acting CVO prior to full appointment) *Mr Nigel G ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Beef Cattle
Beef cattle are cattle raised for meat production (as distinguished from dairy cattle, used for milk production). The meat of mature or almost mature cattle is mostly known as beef. In beef production there are three main stages: cow-calf operations, backgrounding, and feedlot operations. The production cycle of the animals starts at cow-calf operations; this operation is designed specifically to breed cows for their offspring. From here the calves are backgrounded for a feedlot. Animals grown specifically for the feedlot are known as feeder cattle, the goal of these animals is fattening. Animals not grown for a feedlot are typically female and are commonly known as replacement heifers. While the principal use of beef cattle is meat production, other uses include leather, and beef by-products used in candy, shampoo, cosmetics, and insulin. Calving and breeding Besides breeding to meet the demand for beef production, owners also use selective breeding to attain specific trai ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
