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2-Oxopent-4-enoic Acid
2-Oxopent-4-enoic acid (2-oxopent-4-enoate) is formed by the dehydration of 4-hydroxy-2-oxopentanoate by 2-oxopent-4-enoate hydratase or by the hydrolysis of 2-hydroxymuconate semialdehyde by 2-hydroxymuconate-semialdehyde hydrolase In enzymology, a 2-hydroxymuconate-semialdehyde hydrolase () is an enzyme that catalyzes the chemical reaction :2-hydroxymuconate semialdehyde + H2O \rightleftharpoons formate + 2-oxopent-4-enoate Thus, the two substrates of this enzyme are 2- .... References External links Oxopentenoate biocyc.org Alpha-keto acids {{ketone-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pentenoic Acid
Pentenoic acid is any of five mono-carboxylic acids whose molecule has an unbranched chain of five carbons connected by three single bonds and one double bond. That is, any compound with one of the formulas (2-pentenoic), (3-pentenoic), or (4-pentenoic). In the IUPAC-recommended nomenclature, these acids are called pent-2-enoic, pent-3-enoic, and pent-4-enoic, respectively. All these compounds have the empirical formula . Pentenoic acids are technically mono-unsaturated fatty acids, although they are rare or unknown in biological lipids ( fats, waxes, phospholipids, etc.). A salt or ester of such an acid is called a pentenoate. Geometric isomers There are actually two 2-pentenoic acids, distinguished by the conformation of the two single C–C bonds adjacent to the double bond: either on the same side of the double bond's plane (''cis'' or ''Z'' configuration) or on opposite sides of it (''trans'' or ''E'' configuration). Likewise, there are two 3-pentenoic acid ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
(2R)-2-Methylpent-4-enoic Acid
(''2R'')-2-Methylpent-4-enoic acid is an organic acid with the chemical formula C6H10O2. Other names for this molecule include (''R'')-2-methyl-4-pentenoic acid, (''R'')-(−)-2-methyl-4-pentenoic acid, and methylallylacetic acid. Synthesis (''R'')-2-Methylpent-4-enoic acid can be synthesized using a chiral auxiliary such an oxazolidinone derivative, popularized by David Evans David, Dave, or Dai Evans may refer to: Academics * Sir David Emrys Evans (1891–1966), Welsh classicist and university principal * David Evans (microbiologist) (1909–1984), British microbiologist * David Stanley Evans (1916–2004), British a .... One route of synthesis consists of three steps: # acylation of the oxazolidinone using triethylamine as a base, and DMAP as an acyl carrier catalyst # addition of a pentene group via enolate addition using Sodium bis(trimethylsilyl)amide as a base and allyl iodide as the pentene donor # and cleavage of the oxazolidinone by LiOH solution in hydrogen p ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
4-hydroxy-2-oxopentanoate
4-Hydroxy-2-oxopentanoaic acid, also known as 4-hydroxy-2-oxovalerate, is formed by the decarboxylation of 4-oxalocrotonate by 4-oxalocrotonate decarboxylase, is degraded by 4-hydroxy-2-oxovalerate aldolase, forming acetaldehyde and pyruvate and is reversibly dehydrated by 2-oxopent-4-enoate hydratase The enzyme 2-oxopent-4-enoate hydratase () catalyzes the chemical reaction :4-hydroxy-2-oxopentanoate \rightleftharpoons 2-oxopent-4-enoate + H2O This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxy ... to 2-oxopent-4-enoate. References External links 4-Hydroxy-2-ketovalerate biocyc.org Secondary alcohols Alpha-keto acids Gamma hydroxy acids {{ketone-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
2-oxopent-4-enoate Hydratase
The enzyme 2-oxopent-4-enoate hydratase () catalyzes the chemical reaction :4-hydroxy-2-oxopentanoate \rightleftharpoons 2-oxopent-4-enoate + H2O This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is 4-hydroxy-2-oxopentanoate hydro-lyase (2-oxopent-4-enoate-forming). Other names in common use include 2-keto-4-pentenoate hydratase, OEH, 2-keto-4-pentenoate (vinylpyruvate)hydratase, and 4-hydroxy-2-oxopentanoate hydro-lyase. This enzyme participates in nine metabolic pathways: phenylalanine metabolism, benzoate degradation via hydroxylation, biphenyl degradation, toluene and xylene degradation, 1,4-dichlorobenzene degradation, fluorene degradation, carbazole degradation, ethylbenzene degradation, and styrene degradation Styrene () is an organic compound with the chemical formula C6H5CH=CH2. This derivative of benzene is a colorless oily liquid, although aged samples can appear ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
2-hydroxymuconate-semialdehyde Hydrolase
In enzymology, a 2-hydroxymuconate-semialdehyde hydrolase () is an enzyme that catalyzes the chemical reaction :2-hydroxymuconate semialdehyde + H2O \rightleftharpoons formate + 2-oxopent-4-enoate Thus, the two substrates of this enzyme are 2-hydroxymuconate semialdehyde and H2O, whereas its two products are formate and 2-oxopent-4-enoate. This enzyme belongs to the family of hydrolases, specifically those acting on carbon-carbon bonds in ketonic substances. The systematic name of this enzyme class is 2-hydroxymuconate-semialdehyde formylhydrolase. Other names in common use include 2-hydroxy-6-oxohepta-2,4-dienoate hydrolase, 2-hydroxymuconic semialdehyde hydrolase, HMSH, and HOD hydrolase. This enzyme participates in 5 metabolic pathways: benzoate degradation via hydroxylation, toluene and xylene degradation, 1,4-dichlorobenzene degradation, carbazole degradation, and styrene degradation. Structural studies As of late 2007, 10 structures A structure is an arrangemen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
