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1775–1782 North American Smallpox Epidemic
The New World of the Western Hemisphere was devastated by the 1775–1782 North American smallpox epidemic. Estimates based on remnant settlements say 30,000,000 people were estimated to have died in the epidemic that started in 1775. Background Smallpox was a dangerous disease caused by the variola major virus. The most common type of smallpox, ordinary, historically has devastated populations with a 30% death rate. The smallpox virus is transmittable through bodily fluids and materials contaminated with infected materials. Generally, face-to-face contact is required for an individual to contract smallpox as a result of an interaction with another human. Unlike some viruses, humans are the only carriers of variola major. This limits the chances of the virus being unknowingly spread through contact with insect or other animal populations. Persons infected with smallpox are infectious to others for about 24 days after their infection time. However, there is a period of time in which ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
George Washington By Peale 1776
George may refer to: People * George (given name) * George (surname) * George (singer), American-Canadian singer George Nozuka, known by the mononym George * George Washington, First President of the United States * George W. Bush, 43rd President of the United States * George H. W. Bush, 41st President of the United States * George V, King of Great Britain, Ireland, the British Dominions and Emperor of India from 1910-1936 * George VI, King of Great Britain, Ireland, the British Dominions and Emperor of India from 1936-1952 * Prince George of Wales * George Papagheorghe also known as Jorge / GEØRGE * George, stage name of Giorgio Moroder * George Harrison, an English musician and singer-songwriter Places South Africa * George, Western Cape ** George Airport United States * George, Iowa * George, Missouri * George, Washington * George County, Mississippi * George Air Force Base, a former U.S. Air Force base located in California Characters * George (Peppa Pig), a 2-year-old pig ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hudson's Bay Company
The Hudson's Bay Company (HBC; french: Compagnie de la Baie d'Hudson) is a Canadian retail business group. A fur trading business for much of its existence, HBC now owns and operates retail stores in Canada. The company's namesake business division is Hudson's Bay, commonly referred to as The Bay ( in French). After incorporation by English royal charter in 1670, the company functioned as the ''de facto'' government in parts of North America for nearly 200 years until the HBC sold the land it owned (the entire Hudson Bay drainage basin, known as Rupert's Land) to Canada in 1869 as part of the Deed of Surrender, authorized by the Rupert's Land Act 1868. At its peak, the company controlled the fur trade throughout much of the English- and later British-controlled North America. By the mid-19th century, the company evolved into a mercantile business selling a wide variety of products from furs to fine homeware in a small number of sales shops (as opposed to trading posts) acros ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Valley Forge
Valley Forge functioned as the third of eight winter encampments for the Continental Army's main body, commanded by General George Washington, during the American Revolutionary War. In September 1777, Congress fled Philadelphia to escape the British capture of the city. After failing to retake Philadelphia, Washington led his 12,000-man army into winter quarters at Valley Forge, located approximately 18 miles (29 km) northwest of Philadelphia. They remained there for six months, from December 19, 1777 to June 19, 1778. At Valley Forge, the Continentals struggled to manage a disastrous supply crisis while retraining and reorganizing their units. About 1,700 to 2,000 soldiers died from disease, possibly exacerbated by malnutrition. Today, Valley Forge National Historical Park protects and preserves over 3,500 acres of the original encampment site. Pre-encampment In 1777, Valley Forge consisted of a small proto-industrial community located at the juncture of the Valley Cr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Martha Washington
Martha Dandridge Custis Washington (June 21, 1731 — May 22, 1802) was the wife of George Washington, the first president of the United States. Although the title was not coined until after her death, Martha Washington served as the inaugural first lady of the United States. During her lifetime, she was often referred to as "Lady Washington". Martha Dandridge first married Daniel Parke Custis. They had four children, two of whom survived to young adulthood. Daniel's death made Martha a widow at age 26. She brought her vast wealth to her marriage to Washington, which enabled him to buy land to add to his personal estate. She also brought with her 84 dower slaves from Daniel Custis' estate for use during her lifetime. They and their descendants reverted to Custis' estate at her death and were inherited by his heirs. The Washingtons did not have children together, but they did rear her two surviving children, John and Martha. They also helped both of their extended families. Fam ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Inoculation
Inoculation is the act of implanting a pathogen or other microorganism. It may refer to methods of artificially inducing immunity against various infectious diseases, or it may be used to describe the spreading of disease, as in "self-inoculation," the spreading of disease from one part of the body to another, or even to the spreading of bacteria in a Petri dish for culturing purposes. The terms "inoculation", "vaccination", and "immunization" are often used synonymously, but there are some important differences among them. Inoculation is the act of implanting a disease inside a person or animal, vaccination is the act of implanting or giving someone a vaccine specifically, and immunization is what happens to the immune system as a result. Terminology Until the early 1800s inoculation referred only to variolation (from the Latin word ''variola'' = smallpox), the predecessor to the smallpox vaccine. The smallpox vaccine, introduced by Edward Jenner in 1796, was called cowpox inoc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Scarlet Fever
Scarlet fever, also known as Scarlatina, is an infectious disease caused by ''Streptococcus pyogenes'' a Group A streptococcus (GAS). The infection is a type of Group A streptococcal infection (Group A strep). It most commonly affects children between five and 15 years of age. The signs and symptoms include a sore throat, fever, headache, swollen lymph nodes, and a characteristic rash. The face is flushed and the rash is red and blanching. It typically feels like sandpaper and the tongue may be red and bumpy. The rash occurs as a result of capillary damage by exotoxins produced by ''S.pyogenes''. On darker pigmented skin the rash may be hard to discern. Scarlet fever affects a small number of people who have strep throat or streptococcal skin infections. The bacteria are usually spread by people coughing or sneezing. It can also be spread when a person touches an object that has the bacteria on it and then touches their mouth or nose. The diagnosis is typically confirmed by ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Diphtheria
Diphtheria is an infection caused by the bacterium '' Corynebacterium diphtheriae''. Most infections are asymptomatic or have a mild clinical course, but in some outbreaks more than 10% of those diagnosed with the disease may die. Signs and symptoms may vary from mild to severe and usually start two to five days after exposure. Symptoms often come on fairly gradually, beginning with a sore throat and fever. In severe cases, a grey or white patch develops in the throat. This can block the airway and create a barking cough as in croup. The neck may swell in part due to enlarged lymph nodes. A form of diphtheria which involves the skin, eyes or genitals also exists. Complications may include myocarditis, inflammation of nerves, kidney problems, and bleeding problems due to low levels of platelets. Myocarditis may result in an abnormal heart rate and inflammation of the nerves may result in paralysis. Diphtheria is usually spread between people by direct contact or through th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Malaria
Malaria is a mosquito-borne infectious disease that affects humans and other animals. Malaria causes symptoms that typically include fever, tiredness, vomiting, and headaches. In severe cases, it can cause jaundice, seizures, coma, or death. Symptoms usually begin ten to fifteen days after being bitten by an infected mosquito. If not properly treated, people may have recurrences of the disease months later. In those who have recently survived an infection, reinfection usually causes milder symptoms. This partial resistance disappears over months to years if the person has no continuing exposure to malaria. Malaria is caused by single-celled microorganisms of the ''Plasmodium'' group. It is spread exclusively through bites of infected ''Anopheles'' mosquitoes. The mosquito bite introduces the parasites from the mosquito's saliva into a person's blood. The parasites travel to the liver where they mature and reproduce. Five species of ''Plasmodium'' can infect and be spread by h ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Abigail Adams
Abigail Adams ( ''née'' Smith; November 22, [ O.S. November 11] 1744 – October 28, 1818) was the wife and closest advisor of John Adams, as well as the mother of John Quincy Adams. She was a founder of the United States, and was the first second lady of the United States and second first lady of the United States, although such titles were not used at the time. She and Barbara Bush are the only two women to have been married to U.S. presidents and to have been the mothers of other U.S. presidents. Adams's life is one of the most documented of the first ladies: she is remembered for the many letters she wrote to her husband john adams while he stayed in Philadelphia, Pennsylvania, during the Continental Congresses. John frequently sought the advice of Abigail on many matters, and their letters are filled with intellectual discussions on government and politics. Her letters also serve as eyewitness accounts of the American Revolutionary War home front. Surv ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
John Adams
John Adams (October 30, 1735 – July 4, 1826) was an American statesman, attorney, diplomat, writer, and Founding Fathers of the United States, Founding Father who served as the second president of the United States from 1797 to 1801. Before Presidency of John Adams, his presidency, he was a leader of the American Revolution that achieved independence from Kingdom of Great Britain, Great Britain, and during the war served as a diplomat in Europe. He was twice elected vice president of the United States, vice president, serving from 1789 to 1797 in a prestigious role with little power. Adams was a dedicated diarist and regularly corresponded with many important contemporaries, including his wife and adviser Abigail Adams as well as his friend and rival Thomas Jefferson. A lawyer and political activist prior to the Revolution, Adams was devoted to the right to counsel and presumption of innocence. He defied anti-British sentiment and successfully defended British soldiers agai ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lady Mary Wortley Montagu
Lady Mary Wortley Montagu (née Pierrepont; 15 May 168921 August 1762) was an English aristocrat, writer, and poet. Born in 1689, Lady Mary spent her early life in England. In 1712, Lady Mary married Edward Wortley Montagu, who later served as the British ambassador to the Sublime Porte. Lady Mary joined her husband in the Ottoman excursion, where she was to spend the next two years of her life. During her time there, Lady Mary wrote extensively on her experience as a woman in Ottoman Istanbul. After her return to England, Lady Mary devoted her attention to the upbringing of her family before dying of cancer in 1762. Lady Mary is today chiefly remembered for her letters, particularly her ''Turkish Embassy Letters'' describing her travels to the Ottoman Empire, as wife to the British ambassador to Turkey, which Billie Melman describes as "the very first example of a secular work by a woman about the Muslim Orient".Melman, Billie. ''Women's Orients: English Women and the Middle ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Variolation
Variolation was the method of inoculation first used to immunize individuals against smallpox (''Variola'') with material taken from a patient or a recently variolated individual, in the hope that a mild, but protective, infection would result. Variolation is no longer used today. It was replaced by the smallpox vaccine, a safer alternative. This in turn led to the development of the many vaccines now available against other diseases. The procedure was most commonly carried out by inserting/rubbing powdered smallpox scabs or fluid from pustules into superficial scratches made in the skin. The virus was normally spread through the air, infecting first the mouth, nose, or respiratory tract, before spreading throughout the body via the lymphatic system. In contrast, infection of the skin usually led to a milder, localized infection, but, crucially, still induced immunity to the virus. The patient would develop pustules like those caused by naturally acquired smallpox. Eventually, after ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
