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140 (number)
140 (one hundred ndforty) is the natural number following 139 and preceding 141. In mathematics 140 is an abundant number and a harmonic divisor number. It is the sum of the squares of the first seven integers, which makes it a square pyramidal number. 140 is an odious number because it has an odd number of ones in its binary representation. The sum of Euler's totient function φ(''x'') over the first twenty-one integers is 140. 140 is a repdigit in bases 13, 19, 27, 34, 69, and 139. In other fields 140 is also: * The number of varieties of ashes from different varieties of pipe, cigar, and cigarette tobacco included in the Sherlock Holmes monograph. * The former Twitter entry-character limit, a well-known characteristic of the service (based on the text messaging limit) * A film, based on the Twitter entry-character limit, created and edited by Frank Kelly of Ireland * The age that Job died at * The atomic number of unquadnilium, a temporary chemical element * PRO 140 anti ...
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Natural Number
In mathematics, the natural numbers are those numbers used for counting (as in "there are ''six'' coins on the table") and ordering (as in "this is the ''third'' largest city in the country"). Numbers used for counting are called ''Cardinal number, cardinal numbers'', and numbers used for ordering are called ''Ordinal number, ordinal numbers''. Natural numbers are sometimes used as labels, known as ''nominal numbers'', having none of the properties of numbers in a mathematical sense (e.g. sports Number (sports), jersey numbers). Some definitions, including the standard ISO/IEC 80000, ISO 80000-2, begin the natural numbers with , corresponding to the non-negative integers , whereas others start with , corresponding to the positive integers Texts that exclude zero from the natural numbers sometimes refer to the natural numbers together with zero as the whole numbers, while in other writings, that term is used instead for the integers (including negative integers). The natural ...
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PRO 140
Leronlimab (codenamed PRO 140) is a humanized monoclonal antibody targeted against the CCR5 receptor found on T lymphocytes of the human immune system. It is being investigated as a potential therapy in the treatment of COVID-19, triple negative breast cancer, and HIV infection. The United States Food and Drug Administration has designated PRO 140 for fast-track approval. In February 2008, the drug entered Phase 2 clinical trials and a phase 3 trial was begun in 2015. In February 2018, Cytodyn Inc reported that the primary endpoint had been achieved in the PRO 140 pivotal combination therapy trial in HIV infection. In 2020 CytoDyn submitted a fast-track biologics license application for treatment of CCR5-tropic HIV-1 Infection. Development PRO 140 is being developed by Cytodyn Inc. In May 2007, results from the phase I clinical trial of the drug demonstrated "potent, rapid, prolonged, dose-dependent, highly significant antiviral activity" for PRO 140. Participants in the high ...
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United Nations Security Council Resolution 140
United Nations Security Council Resolution 140 concerned admission of the Malagasy Republic (Madagascar) to membership in the United Nations. In the resolution, the Council recommended that the General Assembly approve the Republic's application for membership. The Council adopted Resolution 140 unanimously on June 29, 1960. See also *List of United Nations Security Council Resolutions 101 to 200 This is a list of United Nations Security Council Resolutions 101 to 200 adopted between 24 November 1953 and 15 March 1965. See also * Lists of United Nations Security Council resolutions * List of United Nations Security Council Resoluti ... (1953–1965) References External links * Text of the Resolution at undocs.org 0140 History of Madagascar 0140 1960 in Madagascar 0140 June 1960 events {{UN-resolution-stub ...
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List Of Highways Numbered 140
Route 140 or Highway 140 may refer to: Australia * Hamilton Highway Canada * New Brunswick Route 140 * Ontario Highway 140 * Prince Edward Island Route 140 Costa Rica * National Route 140 Germany * Bundesautobahn 140 India * National Highway 140 (India) Japan * Japan National Route 140 * Fukuoka Prefectural Route 140 * Nara Prefectural Route 140 Malaysia * Malaysia Federal Route 140 United States * Interstate 140 (two current highways) * U.S. Route 140 (former) * Alabama State Route 140 * Arkansas Highway 140 * California State Route 140 * Colorado State Highway 140 * Connecticut Route 140 *Florida State Road 140 (pre-1945) (former) ** Florida State Road 140A (pre-1945) (former) ** County Road 140 (Madison County, Florida) * Georgia State Route 140 * Illinois Route 140 * Indiana State Road 140 * Iowa Highway 140 * K-140 (Kansas highway) * Kentucky Route 140 * Louisiana Highway 140 * Maine State Route 140 * Maryland Route 140 * Massachusetts Route 140 * M-140 (Michi ...
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Dubstep
Dubstep is a genre of electronic dance music that originated in South London in the early 2000s. The style emerged as a UK garage offshoot that blended 2-step rhythms and sparse dub production, as well as incorporating elements of broken beat, grime, and drum and bass.Reynolds, S.(2012),''Energy Flash: A Journey Through Rave Music and Dance Culture,'' Perseus Books; Reprint edition (5 January 2012), pages 511–516, (). In the United Kingdom, the origins of the genre can be traced back to the growth of the Jamaican sound system party scene in the early 1980s. Dubstep is generally characterised by the use of syncopated rhythmic patterns, prominent basslines, and a dark tone. In 2001, this underground sound and other strains of garage music began to be showcased and promoted at London's night club Plastic People, at the "Forward" night (sometimes stylised as FWD>>), and on the pirate radio station Rinse FM, which went on to be considerably influential to the developme ...
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140 (video Game)
''140'' is a platform game independently developed by Jeppe Carlsen, known for his gameplay direction for Playdead's ''Limbo''. The game is described as a "minimalistic platformer", using electronic music to create synesthesia as the player makes their way through four different levels, each with its own sound-track. The game-play has been compared to other similar games which involve music synchronization like '' Sound Shapes'' and the '' Bit.Trip'' series, though with difficult platforming elements comparable to games in the '' Mega Man'' series. The game was released on Microsoft Windows, OS X, and Linux systems in October 2013, on Xbox One in August 2016, on PlayStation 4, Wii U in September 2016, and Nintendo Switch in January 2020. A release on PlayStation Vita and Nintendo 3DS was planned, but later cancelled. Gameplay As described by Carlsen, ''140'' is "an old school platformer", but where the challenge is "in syncing up your moves and jumps to the music-controlled ...
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Egypt
Egypt ( ar, مصر , ), officially the Arab Republic of Egypt, is a transcontinental country spanning the northeast corner of Africa and southwest corner of Asia via a land bridge formed by the Sinai Peninsula. It is bordered by the Mediterranean Sea to the north, the Gaza Strip of Palestine and Israel to the northeast, the Red Sea to the east, Sudan to the south, and Libya to the west. The Gulf of Aqaba in the northeast separates Egypt from Jordan and Saudi Arabia. Cairo is the capital and largest city of Egypt, while Alexandria, the second-largest city, is an important industrial and tourist hub at the Mediterranean coast. At approximately 100 million inhabitants, Egypt is the 14th-most populated country in the world. Egypt has one of the longest histories of any country, tracing its heritage along the Nile Delta back to the 6th–4th millennia BCE. Considered a cradle of civilisation, Ancient Egypt saw some of the earliest developments of writing, agriculture, ur ...
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Directory Assistance
In telecommunications, directory assistance or directory inquiries is a phone service used to find out a specific telephone number and/or address of a residence, business, or government entity. Technology Directory assistance systems incorporate a wide range of automation to reduce the cost of human operators. Almost all systems use custom database software to locate listings quickly. Most directory assistance systems use automated readback systems to give out the phone number. This frees the directory assistance operator to move on to another caller as soon as the correct listing is located. Some systems have "store and forward" technology which records "city and state" the caller is requesting and then plays the city and state speech to the operator before they come online and then say "Residential or business listing?" or simply "What listing please?" Interactive voice response systems have been added to many directory assistance systems. These complex systems use speech reco ...
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Immune System
The immune system is a network of biological processes that protects an organism from diseases. It detects and responds to a wide variety of pathogens, from viruses to parasitic worms, as well as cancer cells and objects such as wood splinters, distinguishing them from the organism's own healthy tissue. Many species have two major subsystems of the immune system. The innate immune system provides a preconfigured response to broad groups of situations and stimuli. The adaptive immune system provides a tailored response to each stimulus by learning to recognize molecules it has previously encountered. Both use molecules and cells to perform their functions. Nearly all organisms have some kind of immune system. Bacteria have a rudimentary immune system in the form of enzymes that protect against virus infections. Other basic immune mechanisms evolved in ancient plants and animals and remain in their modern descendants. These mechanisms include phagocytosis, antimicrobial pe ...
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T Lymphocytes
A T cell is a type of lymphocyte. T cells are one of the important white blood cells of the immune system and play a central role in the adaptive immune response. T cells can be distinguished from other lymphocytes by the presence of a T-cell receptor (TCR) on their cell surface. T cells are born from hematopoietic stem cells, found in the bone marrow. Developing T cells then migrate to the thymus gland to develop (or mature). T cells derive their name from the thymus. After migration to the thymus, the precursor cells mature into several distinct types of T cells. T cell differentiation also continues after they have left the thymus. Groups of specific, differentiated T cell subtypes have a variety of important functions in controlling and shaping the immune response. One of these functions is immune-mediated cell death, and it is carried out by two major subtypes: CD8+ "killer" and CD4+ "helper" T cells. (These are named for the presence of the cell surface proteins CD8 or C ...
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Antibody
An antibody (Ab), also known as an immunoglobulin (Ig), is a large, Y-shaped protein used by the immune system to identify and neutralize foreign objects such as pathogenic bacteria and viruses. The antibody recognizes a unique molecule of the pathogen, called an antigen. Each tip of the "Y" of an antibody contains a paratope (analogous to a lock) that is specific for one particular epitope (analogous to a key) on an antigen, allowing these two structures to bind together with precision. Using this binding mechanism, an antibody can ''tag'' a microbe or an infected cell for attack by other parts of the immune system, or can neutralize it directly (for example, by blocking a part of a virus that is essential for its invasion). To allow the immune system to recognize millions of different antigens, the antigen-binding sites at both tips of the antibody come in an equally wide variety. In contrast, the remainder of the antibody is relatively constant. It only occurs in a few varia ...
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Chemical Element
A chemical element is a species of atoms that have a given number of protons in their nuclei, including the pure substance consisting only of that species. Unlike chemical compounds, chemical elements cannot be broken down into simpler substances by any chemical reaction. The number of protons in the nucleus is the defining property of an element, and is referred to as its atomic number (represented by the symbol ''Z'') – all atoms with the same atomic number are atoms of the same element. Almost all of the baryonic matter of the universe is composed of chemical elements (among rare exceptions are neutron stars). When different elements undergo chemical reactions, atoms are rearranged into new compounds held together by chemical bonds. Only a minority of elements, such as silver and gold, are found uncombined as relatively pure native element minerals. Nearly all other naturally occurring elements occur in the Earth as compounds or mixtures. Air is primarily a mixture o ...
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