α-chlorohydrin
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α-chlorohydrin
3-MCPD (3-monochloropropane-1,2-diol or 3-chloropropane-1,2-diol) is an organic chemical compound with the formula HOCH2CH(OH)CH2Cl. It is a colorless liquid. The compound has attracted notoreity as the most common member of chemical food contaminants known as chloropropanols. It is suspected to be carcinogenic in humans. Accidental and intentional production 3-MCPD, together with its isomer 2-MCPD, is thought to be produced when fat-containing foods are treated at high temperatures with hydrochloric acid. Such treatments are sometimes used to accelerate protein hydrolysis, making food more digestable. In such a treatment chloride is thought to react with the glycerol backbone of lipids to produce 3-MCPD and 2-MCPD. Chlorination of glycerol gives the 3-MCPD: : The same compound can be produced by hydrolysis of epichlorohydrin. Occurrence In 2009, 3-MCPD was found in some East Asian and Southeast Asian sauces such as oyster sauce, Hoisin sauce, and soy sauce. Using hydrochl ...
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Organic Compound
Some chemical authorities define an organic compound as a chemical compound that contains a carbon–hydrogen or carbon–carbon bond; others consider an organic compound to be any chemical compound that contains carbon. For example, carbon-containing compounds such as alkanes (e.g. methane ) and its derivatives are universally considered organic, but many others are sometimes considered inorganic, such as certain compounds of carbon with nitrogen and oxygen (e.g. cyanide ion , hydrogen cyanide , chloroformic acid , carbon dioxide , and carbonate ion ). Due to carbon's ability to catenate (form chains with other carbon atoms), millions of organic compounds are known. The study of the properties, reactions, and syntheses of organic compounds comprise the discipline known as organic chemistry. For historical reasons, a few classes of carbon-containing compounds (e.g., carbonate salts and cyanide salts), along with a few other exceptions (e.g., carbon dioxide, and even ...
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International Agency For Research On Cancer
The International Agency for Research on Cancer (IARC; ) is an intergovernmental agency forming part of the World Health Organization of the United Nations. Its role is to conduct and coordinate research into the causes of cancer. It also cancer registry, collects and publishes disease surveillance, surveillance data regarding the occurrence of cancer worldwide. Its IARC monographs programme identifies carcinogenic hazards and evaluates environmental carcinogen, causes of cancer in humans. IARC has its own governing council, and in 1965 the first members were West Germany, France, Italy, the United Kingdom, and the United States of America. Today, IARC's membership has grown to 29 countries. History In late February 1963, after he experienced his spouse suffering and dying of cancer, journalist and Mouvement de la Paix, peace activist Yves Poggioli sent a letter to Emmanuel d'Astier de La Vigerie, Emmanuel d'Astier de la Vignerie relating his story, and urging support for ...
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King Imperial
King is a royal title given to a male monarch. A king is an absolute monarch if he holds unrestricted governmental power or exercises full sovereignty over a nation. Conversely, he is a constitutional monarch if his power is restrained by fixed laws. Kings are hereditary monarchs when they inherit power by birthright and elective monarchs when chosen to ascend the throne. *In the context of prehistory, antiquity and contemporary indigenous peoples, the title may refer to tribal kingship. Germanic kingship is cognate with Indo-European traditions of tribal rulership (cf. Indic ''rājan'', Gothic ''reiks'', and Old Irish ''rí'', etc.). *In the context of classical antiquity, king may translate in Latin as '' rex'' and in Greek as ''archon'' or ''basileus''. *In classical European feudalism, the title of ''king'' as the ruler of a ''kingdom'' is understood to be the highest rank in the feudal order, potentially subject, at least nominally, only to an emperor (harking back to ...
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Cancer
Cancer is a group of diseases involving Cell growth#Disorders, abnormal cell growth with the potential to Invasion (cancer), invade or Metastasis, spread to other parts of the body. These contrast with benign tumors, which do not spread. Possible Signs and symptoms of cancer, signs and symptoms include a lump, abnormal bleeding, prolonged cough, unexplained weight loss, and a change in defecation, bowel movements. While these symptoms may indicate cancer, they can also have other causes. List of cancer types, Over 100 types of cancers affect humans. Tobacco use is the cause of about 22% of cancer deaths. Another 10% are due to obesity, poor Diet (nutrition), diet, sedentary lifestyle, lack of physical activity or Alcohol abuse, excessive alcohol consumption. Other factors include certain infections, exposure to ionizing radiation, and environmental pollutants. infectious causes of cancer, Infection with specific viruses, bacteria and parasites is an environmental factor cau ...
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1,3-dichloropropane-2-ol
1,3-Dichloropropan-2-ol (1,3-DCP) is an organic compound with the formula HOCH2CHClCH2Cl. It is a colorless liquid. It is an intermediate in the production of epichlorohydrin. 1,3-DCP is a believed to be a carcinogen and mutagen. The International Agency for Research on Cancer classifies it as a Group 2B carcinogen ("possibly carcinogenic to humans"). Along with 3-monochloropropane-1,2-diol (3-MCPD), 1,3-DCP is found in some Asian style sauces such as soy sauce and oyster sauce Oyster sauce describes a number of sauces made by cooking oysters. The most common in modern use is a viscous dark brown condiment made from oyster extracts,The Times, 22 January 1981; ''Cook Accidentally on purpose'' sugar, salt and water, thi .... References {{DEFAULTSORT:Dichloropropan-2-ol, 1, 3- Secondary alcohols Organochlorides IARC Group 2B carcinogens ...
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European Union
The European Union (EU) is a supranational union, supranational political union, political and economic union of Member state of the European Union, member states that are Geography of the European Union, located primarily in Europe. The union has a total area of and an estimated population of over 449million as of 2024. The EU is often described as a ''sui generis'' political entity combining characteristics of both a federation and a confederation. Containing 5.5% of the world population in 2023, EU member states generated a nominal gross domestic product (GDP) of around €17.935 trillion in 2024, accounting for approximately one sixth of global economic output. Its cornerstone, the European Union Customs Union, Customs Union, paved the way to establishing European Single Market, an internal single market based on standardised European Union law, legal framework and legislation that applies in all member states in those matters, and only those matters, where the states ...
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Food Standards Agency
The Food Standards Agency is a non-ministerial government department of the Government of the United Kingdom. It is responsible for protecting public health in relation to food in England, Wales and Northern Ireland. It is led by a board appointed to act in the public interest. Its headquarters are in London, with offices in York, Birmingham, Wales and Northern Ireland. Its counterpart in Scotland is Food Standards Scotland. History The Agency was created based on a report by Professor Philip James, issued after several high-profile outbreaks and deaths from foodborne illness. It was felt that it was inappropriate to have one government department, the Ministry of Agriculture, Fisheries and Food, responsible for both the health of the farming and food processing industries and for food safety. The creation of the Agency was a manifesto commitment of the Labour Party during its 1997 general election campaign; with the party going on to win the election and form a new governm ...
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Department Of Health (United Kingdom)
The Department of Health and Social Care (DHSC) is a Departments of the Government of the United Kingdom, ministerial department of the Government of the United Kingdom. It is responsible for government policy on health and adult social care matters in England, along with a few elements of the same matters which are not otherwise devolved to the Scottish Government, Welsh Government or Northern Ireland Executive. It oversees the English National Health Service (NHS). The department is led by the Secretary of State for Health and Social Care with three ministers of state and three parliamentary under-secretaries of state. The department develops policies and guidelines to improve the quality of care and to meet patient expectations. It carries out some of its work through Quango, arms-length bodies (ALBs), including executive non-departmental public bodies such as NHS England and the NHS Digital, and executive agencies such as the UK Health Security Agency and the Medicines and He ...
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Ministry Of Agriculture, Fisheries And Food (United Kingdom)
The Ministry of Agriculture, Fisheries and Food (MAFF) was a Departments of the United Kingdom Government, United Kingdom government department created by the Board of Agriculture Act 1889 (52 & 53 Vict. c. 30) and at that time called the Board of Agriculture, and then from 1903 the Board of Agriculture and Fisheries, and from 1919 the Ministry of Agriculture and Fisheries. It attained its final name in 1955 with the addition of responsibilities for the British food industry to the existing responsibilities for agriculture and the fishing industry, a name that lasted until the Ministry was dissolved in 2002, at which point its responsibilities had been merged into the Department for Environment, Food and Rural Affairs (Defra). Until the Food Standards Agency was created, the Ministry was responsible for both food production and food safety which was seen by some to give rise to a conflict of interest. The Ministry was scrutinised by the Agriculture Select Committee. Background ...
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Food Standards Australia New Zealand
Food Standards Australia New Zealand (FSANZ) (Māori: ''Te Mana Kounga Kai – Ahitereiria me Aotearoa''), formerly Australia New Zealand Food Authority (ANZFA), is the statutory authority in the Australian Government Health portfolio that is responsible under the Joint Food Standards Treaty for developing the Australia New Zealand Food Standards Code, which contains food standards for Australia and New Zealand. Description FSANZ develops the standards in consultation with experts, other government agencies and stakeholders; the standards are enforced by state and territory departments, agencies and local councils in Australia, the Ministry for Primary Industries in New Zealand, and the Australian Department of Agriculture, Water and the Environment for food imported into Australia. According to legislation, the recommendations made by the body should be open and accountable, and based upon a rigorous scientific assessment of risk to public health and safety, though FSANZ' ...
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Chemosterilant
A chemosterilant is a chemical compound that causes reproductive sterility in an organism. Chemosterilants are particularly useful in controlling the population of species that are known to cause disease, such as insects, or species that are, in general, economically damaging. The sterility induced by chemosterilants can have temporary or permanent effects. Chemosterilants can be used to target one or both sexes, and it prevents the organism from advancing to be sexually functional. They may be used to control pest populations by sterilizing males. The need for chemosterilants is a direct consequence of the limitations of insecticides. Insecticides are most effective in regions in which there is high vector density in conjunction with endemic transmission, and this may not always be the case. Additionally, the insects themselves will develop a resistance to the insecticide either on the target protein level or through avoidance of the insecticide in what is called a behavioral res ...
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Blood–brain Barrier
The blood–brain barrier (BBB) is a highly selective semipermeable membrane, semipermeable border of endothelium, endothelial cells that regulates the transfer of solutes and chemicals between the circulatory system and the central nervous system, thus protecting the brain from harmful or unwanted substances in the blood. The blood–brain barrier is formed by endothelial cells of the Capillary, capillary wall, astrocyte end-feet ensheathing the capillary, and pericytes embedded in the capillary basement membrane. This system allows the passage of some small molecules by passive transport, passive diffusion, as well as the selective and active transport of various nutrients, ions, organic anions, and macromolecules such as glucose and amino acids that are crucial to neural function. The blood–brain barrier restricts the passage of pathogens, the diffusion of solutes in the blood, and Molecular mass, large or Hydrophile, hydrophilic molecules into the cerebrospinal fluid, while a ...
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