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Nitrile hydratase

Nitrile hydratases (NHases; EC4.2.1.84) are mononuclear iron or non-corrinoid cobalt enzymes that catalyse the hydration of diverse nitriles to their corresponding amides: R-C≡N + H2O → R-C(O)NH2Metal cofactorNitrile hydratases use Fe(III) or Co(III) at their active sites.

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