United States military casualties in the War in Afghanistan

Between 7 October 2001 and 30 August 2021, the United States lost a total of 2,459 military personnel in Afghanistan. Of this figure, 1,922 had been killed in action, an additional 20,769 were wounded in action. 18 operatives of the Central Intelligence Agency were also killed during the conflict. Further, there were 1,822 civilian contractor fatalities.

The number of American fatalities reached 1,000 on February 19, 2010, when Reconnaissance Corporal Gregory Stultz of the U.S. Marines was killed by Taliban insurgents during the Battle of Marjah. By April 11, 2011, this figure stood at 1,515, and had surpassed 2,000 by September 2012.

On August 6, 2011, the highest number of American fatalities in a single incident occurred in Wardak Province: 30 Americans (incl. 22 Navy SEALs), seven Afghan soldiers, and a civilian interpreter were all killed when their CH-47 Chinook was shot down; the attack was later claimed by the Taliban.

On August 5, 2014, the highest-ranking American fatality occurred in Kabul: Major General Harold J. Greene of the United States Army was shot dead by 22-year-old Private Rafiqullah of the Afghan National Army; Rafiqullah had carried out the fragging after he was denied leave for Eid al-Fitr.