U.S. Route 2

U.S. Route 2 or U.S. Highway 2 (US 2) is an east–west United States Numbered Highway spanning 2,571 miles (4,138 km) across the northern continental United States. US 2 consists of two segments on either side of a portion of Canada. Unlike some routes, which are disconnected into segments because of encroaching Interstate Highways, the two portions of US 2 were designed to be separate in the original 1926 highway plan.

The western segment of US 2 begins at an interchange with Interstate 5 (I-5) and State Route 529 (Maple Street) in Everett, Washington, and ends at I-75 in St. Ignace, Michigan. The eastern segment of US 2 begins at US 11 in Rouses Point, New York, and ends at I-95 in Houlton, Maine.

As its number indicates, it is the northernmost east–west U.S. Highway in the country. It is the lowest primary-numbered east–west U.S. Highway, whose numbers otherwise end in zero, and was so numbered to avoid a US 0. Sections of US 2 in New England were once New England Route 15, part of the New England road marking system.