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Trichostatin A

Trichostatin A

Trichostatin A (TSA) is an organic compound that serves as an antifungalantibiotic and selectivelyinhibits the class I and II mammalian histone deacetylase (HDAC) families of enzymes, but not class III HDACs (i.e., sirtuins). However, there are recent reports of the interactions of this molecule with sirtuin 6 as well.

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