Puberty blockers

Puberty blockers (also called puberty inhibitors or hormone blockers) are medicines used to postpone puberty. The most commonly used puberty blockers are gonadotropin-releasing hormone (GnRH) agonists, which suppress the natural production of sex hormones, such as androgens (e.g. testosterone) and estrogens (e.g. estradiol). Puberty blockers are used to delay puberty in children with precocious puberty. They are also used to delay the development of unwanted secondary sex characteristics in transgender youth, so as to allow them more time to explore their gender identity under what became known as the Dutch Protocol.