Topic summary
Prostaglandin G2
Prostaglandin G2 (PGG2) is an organic peroxide belonging to the family of prostaglandins. The compound has been isolated as a solid, although it is usually used in vivo. It quickly converts into prostaglandin H2, a process catalyzed by the enzyme cyclooxygenase (COX).
Prostaglandin G2 is produced from the fatty acidarachidonic acid. The reaction, a double oxygenation, requires the enzyme COX, which inserts two molecules of O2 into the C-H bonds of the substrate acid.