Mosopelea

The Mosopelea or Ofo (also Ofogoula) were a Native American people who historically lived near the upper Ohio River. In reaction to Iroquois Confederacy invasions to take control of hunting grounds in the late 17th century, they moved south to the lower Mississippi River. They finally settled in central Louisiana, where they assimilated with the Tunica and the Biloxi. They spoke the Ofo language, generally classified as a Siouan-Catawban language.