Nestorian schism

The Nestorian schism was a gradual distancing between the Church of the East in the Sasanian Empire and the state church of the Roman Empire from the fifth century onwards. The Church of the East came to align itself with Theodore of Mopsuestia, and by extension with his student Nestorius, whereas the Roman imperial church condemned Nestorius and Theodore at the Council of Ephesus and Second Council of Constantinople respectively.