National CJD Surveillance Unit

The National CJD Surveillance Unit (later renamed the National Creutzfeldt-Jakob Disease Research and Surveillance Unit) was a specialist clinical research centre in the United Kingdom, founded in May 1990 to monitor changes in Creutzfeldt–Jakob disease (CJD) that could be related to Bovine spongiform encephalopathy (BSE).

The unit's research identified Variant Creutzfeldt–Jakob disease (vCJD) in 1996, and causally linked the variant to BSE. During the United Kingdom BSE outbreak, the unit recorded 178 deaths due to vCJD. Its funding from the National Institute for Health and Care Research and Scottish Executive Department of Health ceased in 2025.