Topic summary
Muscogee Confederacy

Extracted from the Wikipedia article Muscogee.
Rise of the Muscogee Confederacy
Because of endemic infectious diseases carried unknowingly by the Europeans, but new to the Muscogee, the Spanish expedition resulted in epidemics of smallpox and measles, and a high rate of fatalities among the Indigenous peoples. These losses were exacerbated by the Indian slave trade that colonists conducted in the Southeast during the 17th and 18th centuries. As the survivors and descendants regrouped, the Muscogee Creek Confederacy arose as a loose alliance of Muskogee-speaking peoples.