Leber congenital amaurosis

Leber congenital amaurosis (LCA) is a rare inheritedeye disease that appears at birth or in the first few months of life.

It affects about 1 in 40,000 newborns. LCA was first described by Theodor Leber in the 19th century. It should not be confused with , which is a different disease also described by Theodor Leber.

One form of LCA was successfully treated with gene therapy in 2008.