Interstate 265

Interstate 265 (I-265) is a 31.21-mile (50.23 km) Interstate Highway partially encircling the Louisville metropolitan area. Starting from I-65 in the southern part of Louisville, it runs through Jefferson County, Kentucky, crosses the Ohio River on the Lewis and Clark Bridge into Indiana, meets I-65 for a second time, and then proceeds westbound to terminate at the I-64 interchange.

The entire Kentucky stretch of the road is cosigned with Kentucky Route 841 (KY 841). An additional 10.25-mile-long (16.50 km) stretch of freeway between U.S. Route 31W (US 31W)/US 60/KY 1934 and I-65 in southern Louisville is solely designated as KY 841. The portion from I-71 to the Ohio River, while designated as I-265 by AASHTO, is only signed as KY 841. The highway is named the Gene Snyder Freeway (originally named the Jefferson Freeway), after the former congressman from Kentucky, and usually called "the Snyder" by locals.

Likewise on the Indiana side, the stretch from I-65 to the bridge, while designated as I-265 is signed as State Route 265 (SR 265). The highway is known as the Lee H. Hamilton Freeway after the former congressman from Indiana.

I-265 signage for the section from I-71 to the Indiana I-65 interchange will be replaced by October 2026, when the mileage and exit numbering will be reversed, with mileage and exit numbers increasing from the Indiana/Kentucky border at the Ohio River to the terminus at I-64.