Topic summary

Inflammatory fibroid polyp

Inflammatory fibroid polyp

An inflammatory fibroid polyp(IFP) is an uncommon digestive systemtumor. J. Vanek initially identified it as a separate pathological entity in 1949 when he reported six case reports of eosinophilic infiltration in gastric submucosal granulomas. It is a single, non-encapsulated polypoid lesion that is typically submucosal. It is characterized by a large number of small blood vessels, oedematous connective tissue, and an inflammatory eosinophilic infiltrate.

Inflammatory fibroid polyp has also been referred to as polypoid myo-endothelioma, fibroma with eosinophilic infiltration, inflammatory pseudotumour, myxoma, haemangiopericytoma, eosinophilic granuloma, Vanek's tumour, and gastric eosinophilic submucosal granuloma.

When the lesions are symptomatic, they typically measure less than 3 cm in size and are linked to symptoms such as iron deficiency anemia, bleeding, weight loss, and dyspeptic symptoms. Significant complications like obstruction, intussusception, and even hypovolemic shock can result from larger lesions.