Topic summary
Hybrid sterility

Extracted from the Wikipedia article Reproductive isolation.
Hybrid sterility
A hybrid may have normal viability but is typically deficient in terms of reproduction or is sterile. This is demonstrated by the mule and in many other well known hybrids. In all of these cases sterility is due to the interaction between the genes of the two species involved; to chromosomal imbalances due to the different number of chromosomes in the parent species; or to nucleus-cytoplasmic interactions such as in the case of Culex described above.