Topic summary

Hemoglobin A1c

Hemoglobin A1c

Extracted from the Wikipedia article Glycated hemoglobin.

HbA1c

Hemoglobin A1c (HbA1c) was originally (1958) the designation of one of the factions formed, when doing cation exchange chromatography. The species forming this faction were only later described in detail. It has since been rendered more precisely to be "a stable minor Hb variant formed in vivo by post-translational modification by glucose", containing primarily glycated N-terminal β-chains.