Upstate South Carolina

CSA in South Carolina, United StatesGreenville–SpartanburgMetropolitan AreaCSAGreenville–Spartanburg–Anderson, SCCombined Statistical Area Greenville Spartanburg Map of Greenville–Spartanburg–Anderson, SC CSA City of Greenville City of Spartanburg City of Anderson Greenville–Anderson–Greer, SC MSA Spartanburg, SC MSA Greenwood, SC μSA Seneca, SC μSA Gaffney, SC μSA Country United StatesState South CarolinaPrincipal cities - Greenville - Spartanburg - Anderson - Mauldin - Easley - Clemson - Gaffney - Greer - Greenwood - Seneca Area • Total6,168 sq mi (15,980 km2) • Land6,008 sq mi (15,560 km2) • Water141 sq mi (370 km2) 2.2%Population (2020) • CSA1,487,610 (39th)GDP • MSA$57.403 billion (2022) • CSA$76.888 billion (2022)Time zoneUTC−5 (EST) • Summer (DST)UTC−4 (EDT)Area codes864 and 821 The Upstate, historically known as the Upcountry, is a region of the U.S. state of South Carolina, comprising the northwesternmost area of the state. Although loosely defined among locals, the general definition includes the 10 counties of the commerce-rich I-85 corridor in the northwest corner of South Carolina. This definition coincided with the Greenville-Spartan