Topic summary

Glycerol-3-phosphate O-acyltransferase

Glycerol-3-phosphate O-acyltransferase

In enzymology, a glycerol-3-phosphate O-acyltransferase (EC2.3.1.15) is an enzyme that catalyzes the chemical reaction

acyl-CoA + sn-glycerol 3-phosphate CoA + 1-acyl-sn-glycerol 3-phosphate

Thus, the two substrates of this enzyme are acyl-CoA and sn-glycerol 3-phosphate, whereas its two products are CoA and 1-acyl-sn-glycerol 3-phosphate.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acyl-CoA:sn-glycerol-3-phosphate 1-O-acyltransferase. Other names in common use include alpha-glycerophosphate acyltransferase, 3-glycerophosphate acyltransferase, ACP:sn-glycerol-3-phosphate acyltransferase, glycerol 3-phosphate acyltransferase, glycerol phosphate acyltransferase, glycerol phosphate transacylase, glycerophosphate acyltransferase, glycerophosphate transacylase, sn-glycerol 3-phosphate acyltransferase, and sn-glycerol-3-phosphate acyltransferase. This enzyme participates in and glycerophospholipid metabolism. The later pathways in human is part of the WikiPathways machine readable pathway collection.