Topic summary
Double helix

Extracted from the Wikipedia article Nucleic acid double helix.
References
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However, the discovery of topoisomerases took 'the sting' out of the topological objection to the plectonaemic double helix. The more recent solution of the single crystal X-ray structure of the nucleosome core particle showed nearly 150 base pairs of the DNA (i.e., about 15 complete turns), with a structure that is in all essential respects the same as the Watson–Crick model. This dealt a death blow to the idea that other forms of DNA, particularly double-helical DNA, exist as anything other than local or transient structures.
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