Coomassie brilliant blue

Names Other names

C.I. 42655, C.I. Acid Blue 90
Brilliant indocyanine G, Brillantindocyanin G
Xylene Brilliant Cyanine G, Serva Blue G

Identifiers

3D model (JSmol)

CCN(CC1=CC(=CC=C1)S(=O)(=O)O)C2=CC(=C(C=C2)/C(=C\3/C=CC(=[N+](CC)CC4=CC(=CC=C4)S(=O)(=O)O)C=C3C)/C5=CC=C(C=C5)NC6=CC=C(C=C6)OCC)C

Properties

C₄₇H₅₀N₃NaO₇S₂ (Sodium salt) Molar mass856.03 g/mol

Slightly soluble in cold, soluble in hot (bright blue) Solubility in ethanol Soluble Pharmacology Legal status

Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Coomassie brilliant blue is the name of two similar triphenylmethane dyes that were developed for use in the textile industry but are now commonly used for staining proteins in analytical biochemistry. Coomassie brilliant blue G-250 differs from Coomassie brilliant blue R-250 by the addition of two methyl groups. The name "Coomassie" is a registered trademark of Imperial Chemical Industries.