Cardinals–Rams rivalry

The Cardinals–Rams rivalry is a National Football League (NFL) rivalry between the Arizona Cardinals and Los Angeles Rams.

One of the oldest matchups in the league, the two teams met for the first time during the NFL's infancy in 1937 back when the Cardinals were located in Chicago, and the Rams in Cleveland. State Farm Stadium and SoFi Stadium are only 375 miles apart, mostly along I-10. Both teams were also previously based in St. Louis and left to play in the Western United States.

The Rams lead the overall series 53–41–2. The two teams have met twice in the playoffs, with the Rams winning both games.