Topic summary
Aspartate pathway
Extracted from the Wikipedia article Amino acid synthesis.
Oxaloacetate/aspartate: lysine, asparagine, methionine, threonine, and isoleucine
The associated enzymes are subject to regulation via feedback inhibition and/or repression at the genetic level. As is typical in highly branched metabolic pathways, additional regulation at each branch point of the pathway. This type of regulatory scheme allows control over the total flux of the aspartate pathway in addition to the total flux of individual amino acids. The aspartate pathway uses L-aspartic acid as the precursor for the biosynthesis of one-fourth of the building block amino acids.