3-oxoacyl-(acyl-carrier-protein) reductase

In enzymology, a 3-oxoacyl-[acyl-carrier-protein] reductase (EC1.1.1.100) is an enzyme that catalyzes the chemical reaction

3-oxoacyl-[acyl-carrier-protein](ACP) + NADPH + H${\displaystyle ightleftharpoons }$ (3R)-3-hydroxyacyl-[acyl-carrier-protein](ACP) + NADP

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group as hydride donor with NAD or NADP as hydride acceptor. The systematic name of this enzyme class is (3R)-3-hydroxyacyl-[acyl-carrier-protein]:NADP oxidoreductase. Other names in common use include beta-ketoacyl-[acyl-carrier protein](ACP) reductase, beta-ketoacyl acyl carrier protein (ACP) reductase, beta-ketoacyl reductase, beta-ketoacyl thioester reductase, beta-ketoacyl-ACP reductase, beta-ketoacyl-acyl carrier protein reductase, 3-ketoacyl acyl carrier protein reductase, 3-ketoacyl ACP reductase, NADPH-specific 3-oxoacyl-[acylcarrier protein]reductase, and 3-oxoacyl-[ACP]reductase. This enzyme participates in fatty acid biosynthesis and polyunsaturated fatty acid biosynthesis.