2020–21 Northwestern Wildcats women's basketball team

The 2020–21 Northwestern Wildcats women's basketball team represented Northwestern University during the 2020–21 NCAA Division I women's basketball season. The Wildcats were led by 13th-year head coach Joe McKeown. They played their home games at Welsh–Ryan Arena as members of the Big Ten Conference.

They finished the season 16–9, 11–7 in Big Ten play to finish in fifth place. They received a bye into the second round of the Big Ten women's tournament, where they defeated Illinois and Michigan before losing to eventual champions Maryland in the semifinals. They received an at-large bid to the NCAA tournament. As the seven seed in the Alamo Regional they defeated ten seed UCF in the first round before losing to two seed Louisville in the second round to end their season.